Important for substrate specificity; cannot use PPi as phosphoryl donor
Pyridoxamine 5'-phosphate oxidase putative
Periplasmic binding protein domain-containing protein
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
TRAP C4-dicarboxylate transport system permease DctM subunit
Penicillin-binding protein transpeptidase
Pseudouridine synthase I TruA alpha/beta
Helix-turn-helix conjugative transposon-like
Large ribosomal subunit protein uL15/eL18
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Sporulation stage II protein D amidase enhancer LytB N-terminal
Polymerase/histidinol phosphatase N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Transposase IS204/IS1001/IS1096/IS1165 DDE
Transposase IS204/IS1001/IS1096/IS1165 helix-turn-helix
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
Major facilitator superfamily (MFS) profile
Helix-hairpin-helix DNA-binding motif class 1
HicB-like antitoxin of toxin-antitoxin system
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Membrane fusion protein biotin-lipoyl like
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Proton acceptor; for glutaminase activity
Transposase IS116/IS110/IS902 C-terminal
Cell envelope-related transcriptional attenuator
N6 adenine-specific DNA methyltransferase N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Aspartate/homoserine dehydrogenase NAD-binding
YbaK/aminoacyl-tRNA synthetase-associated
Flagellar basal-body/hook protein C-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
DNA mismatch repair proteins mutS family
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
Essential for prephenate dehydratase activity
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Threonine/serine exporter-like N-terminal
Large ribosomal subunit protein uL6 alpha-beta
L-seryl-tRNA selenium transferase N-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
NIF system FeS cluster assembly NifU N-terminal
Glycosyl hydrolase family 98 putative carbohydrate-binding module
Resolvase/invertase-type recombinase catalytic
Flagellar basal body rod protein N-terminal
Reversibly protonated during proton transport
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
O-(5'-phospho-DNA)-tyrosine intermediate
Gamma-glutamylcyclotransferase AIG2-like
O-(phosphoribosyl dephospho-coenzyme A)serine
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Polysaccharide biosynthesis protein C-terminal
Thymidylate synthase/dCMP hydroxymethylase
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Type I restriction enzyme R protein C-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Bacterial type II secretion system protein E
Phosphocysteine intermediate; for EIIB activity
Pyrimidine nucleoside phosphorylase C-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Transcriptional regulator TetR C-terminal Firmicutes type
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Gfo/Idh/MocA-like oxidoreductase C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Important for autoinhibition of adenylyltransferase activity
RNA 2-O ribose methyltransferase substrate binding
Glucosamine/galactosamine-6-phosphate isomerase
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Schiff-base intermediate with acetaldehyde
S-adenosylmethionine-dependent methyltransferase
Glycosyl transferase family 3 N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Aminoacyl-transfer RNA synthetases class-II family profile
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Choloylglycine hydrolase/NAAA C-terminal
Endoribonuclease L-PSP/chorismate mutase-like
Pyruvate/ketoisovalerate oxidoreductase catalytic
Cation-transporting P-type ATPase N-terminal
Heat-inducible transcription repressor HrcA C-terminal
FAD-dependent oxidoreductase 2 FAD binding
Thiamine pyrophosphate enzyme TPP-binding
Alpha-D-phosphohexomutase alpha/beta/alpha
Tryptophan synthase beta chain-like PALP
Transcription regulator AsnC/Lrp ligand binding
ATPsynthase alpha/beta subunit N-terminal extension
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Plays an important role in substrate specificity
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Glycine cleavage T-protein C-terminal barrel
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Phosphomannose isomerase type I catalytic
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
Ribosomal RNA adenine methylase transferase N-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Phosphatidic acid phosphatase type 2/haloperoxidase
Schiff-base intermediate with substrate; via pyruvic acid
Mandelate racemase/muconate lactonizing enzyme C-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Aconitase A/isopropylmalate dehydratase small subunit swivel
Chromosomal replication initiator DnaA C-terminal
Superoxide dismutase copper/zinc binding
Small ribosomal subunit protein uS4 N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Sporulation stage IV protein A C-terminal
Transcriptional coactivator p15 (PC4) C-terminal
Release factor glutamine methyltransferase N-terminal
Flagellar motor switch protein FliN-like C-terminal
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
ABC transporter substrate-binding protein PnrA-like
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Septum formation inhibitor MinC C-terminal
Nuclease-associated modular DNA-binding 1
Restriction endonuclease type II DpnII-like
DNA replication/recombination mediator RecO N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Could be important to modulate the pK values of the two catalytic cysteine residues
Signal transduction histidine kinase internal region
Putative aromatic acid exporter C-terminal
Polysaccharide chain length determinant N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Sporulation transcription regulator WhiA N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Exonuclease VII large subunit C-terminal
Large ribosomal subunit protein uL2 C-terminal
Polysaccharide biosynthesis protein CapD-like
Interaction with polymerase core subunit RpoC
Large ribosomal subunit protein bL9 C-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Translation elongation factor P/YeiP central
Cysteine-rich secretory protein family protein
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Prepilin type IV endopeptidase peptidase
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
ATP synthase F1 complex delta/epsilon subunit N-terminal
Type I restriction modification DNA specificity
Mannose-6-phosphate isomerase type II C-terminal
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Sialic acid-binding periplasmic protein SiaP
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Schiff-base intermediate with dihydroxyacetone-P
Phosphotransferase system enzyme I N-terminal
DNA primase/polymerase bifunctional N-terminal
Inosine monophosphate cyclohydrolase-like
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Phosphatidylglycerol lysyltransferase C-terminal
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
5-glutamyl coenzyme A thioester intermediate
Sporulation initiation factor Spo0A C-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cyclic nucleotide phosphodiesterase C-terminal
Prokaryotic-type class I peptide chain release factors
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Dinitrogenase iron-molybdenum cofactor biosynthesis
RND efflux pump membrane fusion protein barrel-sandwich
tRNA pseudouridylate synthase B C-terminal