Major facilitator superfamily (MFS) profile
Aconitase A/isopropylmalate dehydratase small subunit swivel
Glycosyl transferase family 3 N-terminal
Transposase IS116/IS110/IS902 C-terminal
Chalcone isomerase domain-containing protein
RNA polymerase sigma factor 70 region 4 type 2
Phosphatidic acid phosphatase type 2/haloperoxidase
Polypeptide-transport-associated ShlB-type
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Arsenosugar biosynthesis radical SAM protein ArsS-like C-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Cytochrome c-type biogenesis protein CcmF C-terminal
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Thiamin/hydroxymethyl pyrimidine-binding YkoF putative
Aminoacyl-transfer RNA synthetases class-II family profile
Solute-binding protein family 3/N-terminal domain-containing protein
Bacterial type II secretion system protein E
TonB-dependent receptor-like beta-barrel
Alpha-D-phosphohexomutase alpha/beta/alpha
Acyl-ester intermediate; for transpeptidase activity
Penicillin-binding protein transpeptidase
Proton donor; for transglycosylase activity
Alpha-glycerophosphate oxidase C-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
NADH-rubredoxin oxidoreductase C-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
TonB system biopolymer transport component
Putative beta-barrel assembly-enhancing protease
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Seems to be a necessary countercharge to the potassium cations
Cysteine sulfenic acid (-SOH) intermediate
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
RND efflux pump membrane fusion protein barrel-sandwich
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Interaction with polymerase core subunit RpoC
Bacterial virulence factor lipase N-terminal
Bacterial virulence factor lipase N-terminal domain-containing protein
Chromosomal replication initiator protein DnaA
Arginine decarboxylase C-terminal helical
UDP N-acetylglucosamine O-acyltransferase C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Erythronate-4-phosphate dehydrogenase dimerisation
Type II secretion system protein GspG C-terminal
Transglutaminase-like domain-containing protein
RNA 2-O ribose methyltransferase substrate binding
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
ABC-type glycine betaine transport system substrate-binding
Glycine cleavage T-protein C-terminal barrel
Solute-binding protein family 3/N-terminal
Signal transduction histidine kinase internal region
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Could be important to modulate the pK values of the two catalytic cysteine residues
SUF system FeS cluster assembly SufBD N-terminal
Nitrite/Sulfite reductase ferredoxin-like
S-adenosyl-L-homocysteine hydrolase NAD binding
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Inner membrane protein YgaP-like transmembrane
Histidine-specific methyltransferase SAM-dependent
Prokaryotic-type class I peptide chain release factors
Outer membrane protein beta-barrel domain-containing protein
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Polysaccharide chain length determinant N-terminal
N-end rule aminoacyl transferase C-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Lysidine-tRNA(Ile) synthetase C-terminal
tRNA(Met) cytidine acetyltransferase TmcA N-terminal
Lipocalin-like domain-containing protein
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Outer membrane protein assembly factor BamA
Disulphide bond isomerase DsbC/G N-terminal
Pyridoxamine 5'-phosphate oxidase Alr4036 family FMN-binding
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Cytochrome b561 bacterial/Ni-hydrogenase
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
S-adenosylmethionine-dependent methyltransferase
Outer membrane lipoprotein-sorting protein
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-91)
Nucleoside-binding outer membrane protein
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Translation elongation factor EFTs/EF1B dimerisation
Flagella basal body P-ring formation protein FlgA
Flagella basal body P-ring formation protein FlgA C-terminal
Alginate export domain-containing protein
Peptide methionine sulphoxide reductase MsrA
Interacts with tRNA; defines subfamily-specific binding signature
Large ribosomal subunit protein uL2 C-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Adaptive response protein AidB N-terminal
Translation elongation factor P/YeiP central
Cytochrome C biogenesis protein transmembrane
Thiol:disulfide interchange protein DsbD N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Leucine-binding protein domain-containing protein
Positions MEP for the nucleophilic attack
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Phosphate ABC transporter substrate-binding protein
Sodium symporter small subunit predicted
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Saccharopine dehydrogenase-like C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
7 transmembrane helices usually fused to an inactive transglutaminase
Inactive transglutaminase fused to 7 transmembrane helices
Outer membrane protein OmpA-like transmembrane
Outer membrane protein OmpA-like transmembrane domain-containing protein
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Polysaccharide biosynthesis protein CapD-like
Large ribosomal subunit protein uL6 alpha-beta
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Calcineurin-like phosphoesterase domain-containing protein
Tryptophan synthase beta chain-like PALP
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Type IV secretion system coupling protein TraD DNA-binding
Type III secretion system flagellar brake protein YcgR PilZN
Flagellar hook-length control protein-like C-terminal
Sodium/calcium exchanger membrane region
Lytic transglycosylase superhelical linker
Ribosomal protein L7/L12 C-terminal domain-containing protein
Acyl-CoA dehydrogenase C-terminal bacterial-type
Pyruvate dehydrogenase E1 component middle
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
Pyridine nucleotide-disulphide oxidoreductase dimerisation
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Shikimate dehydrogenase substrate binding N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
CobB/CobQ-like glutamine amidotransferase
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Urease accessory protein UreH-like transmembrane
Schiff-base intermediate with substrate; via pyruvic acid
Outer membrane assembly lipoprotein YfiO
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Essential for prephenate dehydratase activity
Quercetin 2,3-dioxygenase C-terminal cupin
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Release factor glutamine methyltransferase N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Electron transfer via tryptophanyl radical
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
DNA replication/recombination mediator RecO N-terminal
DNA-directed DNA polymerase family A palm
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Carbamoyl-phosphate synthase small subunit N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
DNA mismatch repair proteins mutS family
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Na+/H+ antiporter MnhB subunit-related protein
Transposase IS204/IS1001/IS1096/IS1165 DDE
Gamma-glutamylcyclotransferase AIG2-like
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
Anthranilate synthase component I N-terminal
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Glucose-methanol-choline oxidoreductase N-terminal
Glycosyltransferase subfamily 4-like N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Flagellar motor switch protein FliN-like C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Prepilin type IV endopeptidase peptidase
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Outer membrane beta-barrel domain-containing protein
NIF system FeS cluster assembly NifU C-terminal
Important for substrate binding and specificity
Polymerase/histidinol phosphatase N-terminal
Type II secretion system protein GspI C-terminal
Large ribosomal subunit protein uL15/eL18
Metallo-beta-lactamase domain-containing protein
PhoD-like phosphatase metallophosphatase
Glycosyltransferase 2-like prokaryotic type
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Aminoacyl-tRNA synthetase class I anticodon-binding
NAD(P) transhydrogenase alpha subunit C-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Sugar fermentation stimulation protein C-terminal
6-hydroxymethylpterin diphosphokinase MptE-like
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Pyruvate phosphate dikinase AMP/ATP-binding
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Fibrobacter succinogenes major paralogous domain-containing protein
ABC-type transport system involved in resistance to organic solvents, auxiliary component
Thymidylate synthase/dCMP hydroxymethylase
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
DNA polymerase III delta subunit C-terminal
RNA binding; important for wobble base 34 recognition
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Exonuclease VII large subunit C-terminal
1-phosphatidylinositol phosphodiesterase
Glyoxalase/fosfomycin resistance/dioxygenase
Peptidase M10 metallopeptidase domain-containing protein
RNA methyltransferase SpoU/TrmH type C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Small ribosomal subunit protein uS4 N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Gly-cisPro motif, important for rejection of L-amino acids
Plays an important role in substrate specificity
Important for interaction with partner proteins
Gamma-butyrobetaine hydroxylase-like N-terminal
Right handed beta helix domain-containing protein
Regulator of nucleoside diphosphate kinase N-terminal
NarX-like N-terminal domain-containing protein
ABC-type uncharacterised transport system
Survival protein SurE-like phosphatase/nucleotidase
Type II secretion system protein GspC N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Activator of Hsp90 ATPase homologue 1-like C-terminal
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Cobalamin-independent methionine synthase MetE C-terminal/archaeal