Choloylglycine hydrolase/NAAA C-terminal
Cell envelope-related transcriptional attenuator
Cell envelope-related transcriptional attenuator domain-containing protein
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Could be important to modulate the pK values of the two catalytic cysteine residues
Aminoacyl-transfer RNA synthetases class-II family profile
Peptidase M1 membrane alanine aminopeptidase
Major facilitator superfamily (MFS) profile
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Solute-binding protein family 5 domain-containing protein
Phosphatidic acid phosphatase type 2/haloperoxidase
Terminase large subunit-like endonuclease
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Thymidylate synthase/dCMP hydroxymethylase
Glycerophosphoryl diester phosphodiesterase membrane
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Penicillin-binding protein transpeptidase
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Phosphocysteine intermediate; for EIIB activity
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Bacterial type II secretion system protein E
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Gly-cisPro motif, important for rejection of L-amino acids
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Lacto-N-biose phosphorylase-like N-terminal TIM barrel
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
RNA 2-O ribose methyltransferase substrate binding
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Large ribosomal subunit protein uL6 alpha-beta
DNA replication/recombination mediator RecO N-terminal
Gram-positive cocci surface proteins LPxTG
Gram-positive cocci surface proteins LPxTG domain-containing protein
Gram-positive pilin subunit D1 N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Heat-inducible transcription repressor HrcA C-terminal
Prokaryotic-type class I peptide chain release factors
Reversibly protonated during proton transport
Large ribosomal subunit protein uL2 C-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Glycosyltransferase subfamily 4-like N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Anthranilate synthase component I N-terminal
Alpha-glycerophosphate oxidase C-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Alpha-D-phosphohexomutase alpha/beta/alpha
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Carbamoyl-phosphate synthase small subunit N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
SUF system FeS cluster assembly SufBD N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Interaction with polymerase core subunit RpoC
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Pyruvate dehydrogenase E1 component middle
Polymerase/histidinol phosphatase N-terminal
Cytochrome C biogenesis protein transmembrane
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Zinc ABC transporter substrate-binding protein
SsuA/THI5-like domain-containing protein
Electron transfer flavoprotein alpha/beta-subunit N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Sporulation transcription regulator WhiA N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Pyruvate phosphate dikinase AMP/ATP-binding
Essential for prephenate dehydratase activity
Aspartate/homoserine dehydrogenase NAD-binding
ABC transporter substrate-binding protein
ABC transporter substrate-binding protein PnrA-like
NIF system FeS cluster assembly NifU N-terminal
Phosphoribosylformylglycinamidine synthase linker
Endoribonuclease L-PSP/chorismate mutase-like
Translation elongation factor P/YeiP central
Schiff-base intermediate with acetaldehyde
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
PrcB C-terminal domain-containing protein
DNA-directed DNA polymerase family A palm
Galactofuranosyltransferase GlfT2 N-terminal
Galactofuranosyltransferase-2 C-terminal
Tryptophan synthase beta chain-like PALP
Small ribosomal subunit protein uS4 N-terminal
Large ribosomal subunit protein uL15/eL18
Trigger factor ribosome-binding bacterial
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Peptide methionine sulphoxide reductase MsrA
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Resolvase/invertase-type recombinase catalytic
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
RNA polymerase sigma factor 70 region 4 type 2
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Ribose-phosphate pyrophosphokinase N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Could play a key role in the communication between the regulatory and the substrate sites
Plays an important role in substrate specificity
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Solute-binding protein family 3/N-terminal
Solute-binding protein family 3/N-terminal domain-containing protein
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Pyrimidine nucleoside phosphorylase C-terminal
RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein
Shikimate dehydrogenase substrate binding N-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Electron transfer via tryptophanyl radical
Proton acceptor; for glutaminase activity
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Microcystin LR degradation protein MlrC C-terminal
Microcystin LR degradation protein MlrC N-terminal
Helix-hairpin-helix DNA-binding motif class 1
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Alanyl-transfer RNA synthetases family profile
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
ATP synthase F1 complex delta/epsilon subunit N-terminal
Cysteine sulfenic acid (-SOH) intermediate
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Glycosyl hydrolase family 98 putative carbohydrate-binding module domain-containing protein
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Schiff-base intermediate with substrate; via pyruvic acid
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase