Lytic transglycosylase superhelical linker
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
NIF system FeS cluster assembly NifU C-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Aminoacyl-transfer RNA synthetases class-II family profile
Solute-binding protein family 5 domain-containing protein
Aromatic amino acid beta-eliminating lyase/threonine aldolase
YbaK/aminoacyl-tRNA synthetase-associated
Quercetin 2,3-dioxygenase C-terminal cupin
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
ABC-type glycine betaine transport system substrate-binding
Sodium/calcium exchanger membrane region
Adaptive response protein AidB N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
DNA-directed DNA polymerase family A palm
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Organic solvent tolerance-like N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Outer-membrane lipoprotein Wza C-terminal
Major facilitator superfamily (MFS) profile
Bacterial type II secretion system protein E
Outer-membrane lipoprotein carrier protein
Plays an important role in substrate specificity
Anthranilate synthase component I N-terminal
Amino acid ABC transporter substrate-binding protein
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
DNA replication/recombination mediator RecO N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Outer membrane protein assembly factor BamB
Peptidase S9 prolyl oligopeptidase catalytic
ABC-type transport auxiliary lipoprotein component
ABC-type transport auxiliary lipoprotein component domain-containing protein
Isocitrate dehydrogenase kinase/phosphatase (AceK) kinase
Isocitrate dehydrogenase kinase/phosphatase (AceK) regulatory
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Plays an important role in discriminating NADH against NADPH
Putative beta-barrel assembly-enhancing protease
Urease accessory protein UreH-like transmembrane
Cation-transporting P-type ATPase N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Tryptophan synthase beta chain-like PALP
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Pyruvate phosphate dikinase AMP/ATP-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Erythronate-4-phosphate dehydrogenase dimerisation
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
DNA polymerase III subunit delta C-terminal
Pseudouridine synthase I TruA alpha/beta
Cytochrome b561 bacterial/Ni-hydrogenase
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Glycosyl transferase family 3 N-terminal
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Required for zinc-mediated homotetramerization and catalytic activity
Polysaccharide chain length determinant N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Membrane fusion protein biotin-lipoyl like
Cysteine sulfenic acid (-SOH) intermediate
Siroheme decarboxylase AsnC-like ligand binding
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-95)
Gamma-glutamylcyclotransferase AIG2-like
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Glucose-methanol-choline oxidoreductase N-terminal
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Lipopolysaccharide export system protein LptA
N-end rule aminoacyl transferase C-terminal
RNA polymerase sigma factor 70 region 4 type 2
Ribonucleotide reductase large subunit C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Formamidopyrimidine-DNA glycosylase catalytic
Acyl-CoA dehydrogenase C-terminal bacterial-type
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
SUF system FeS cluster assembly SufBD N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Penicillin-binding protein transpeptidase
Peptide methionine sulphoxide reductase MsrA
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
NADH:flavin oxidoreductase/NADH oxidase N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Heme-copper oxidase subunit III family profile
L,D-transpeptidase catalytic domain-containing protein
Penicillin-binding protein activator LpoB
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Putative ATP-dependent zinc protease domain-containing protein
Inner membrane protein YgaP-like transmembrane
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
TonB-dependent receptor-like beta-barrel
Glycine cleavage T-protein C-terminal barrel
Glycosyl hydrolase family 30 beta sandwich
Glucosamine/galactosamine-6-phosphate isomerase
Release factor glutamine methyltransferase N-terminal
Interacts with tRNA; defines subfamily-specific binding signature
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Disulphide bond isomerase DsbC/G N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Translation elongation factor P/YeiP central
Ribosomal RNA small subunit methyltransferase E methyltransferase
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
HTH-type transcriptional regulator MT1864/Rv1816-like C-terminal
Arginine decarboxylase C-terminal helical
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Gamma-butyrobetaine hydroxylase-like N-terminal
tRNA(Met) cytidine acetyltransferase TmcA N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Glucan biosynthesis periplasmic MdoG C-terminal
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Pyruvate dehydrogenase E1 component middle
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Saccharopine dehydrogenase-like C-terminal
Sugar fermentation stimulation protein C-terminal
Alpha-glycerophosphate oxidase C-terminal
Membrane-bound lytic murein transglycosylase F
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Murein L,D-transpeptidase catalytic domain family protein
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Proton acceptor; for glutaminase activity
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Sodium symporter small subunit predicted
Survival protein SurE-like phosphatase/nucleotidase
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Histidine-specific methyltransferase SAM-dependent
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
Outer membrane protein assembly factor BamD
Large ribosomal subunit protein uL2 C-terminal
Outer membrane protein beta-barrel domain-containing protein
Peptide methionine sulfoxide reductase MsrA
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Alanyl-transfer RNA synthetases family profile
Prepilin type IV endopeptidase peptidase
Capsule biosynthesis GfcC-like C-terminal
Capsule biosynthesis GfcC-like C-terminal domain-containing protein
Polymerase/histidinol phosphatase N-terminal
Translocation and assembly module subunit TamA
Important for substrate binding and specificity
Reversibly protonated during proton transport
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Proline utilization A proline dehydrogenase N-terminal
Arsenite oxidase subunit AioA/Iodate reductase subunit IdrA 3Fe-4S cluster
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
S-adenosylmethionine-dependent methyltransferase
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Prokaryotic-type class I peptide chain release factors
Poly-beta-hydroxybutyrate polymerase N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Interaction with polymerase core subunit RpoC
DNA polymerase III delta subunit C-terminal
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Glycosyltransferase subfamily 4-like N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
High potential iron-sulfur proteins family profile
Ribose-phosphate pyrophosphokinase N-terminal
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Endolytic peptidoglycan transglycosylase RlpA
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Alpha-D-phosphohexomutase alpha/beta/alpha
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Protein-PII uridylyltransferase N-terminal
Na+/H+ antiporter MnhB subunit-related protein
Glycine zipper 2TM domain-containing protein
Peptidoglycan binding-like domain-containing protein
SsuA/THI5-like domain-containing protein
RlpA-like protein double-psi beta-barrel
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Chromosomal replication initiator DnaA C-terminal
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
7 transmembrane helices usually fused to an inactive transglutaminase
Inactive transglutaminase fused to 7 transmembrane helices
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Phosphoethanolamine transferase N-terminal
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
UDP N-acetylglucosamine O-acyltransferase C-terminal
Aromatic hydrocarbon degradation protein
Schiff-base intermediate with substrate; via pyruvic acid
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Solute-binding protein family 3/N-terminal domain-containing protein
Mannose-6-phosphate isomerase type II C-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Exonuclease VII large subunit C-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Electron transfer via tryptophanyl radical
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Contractile injection system tube protein N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
RNA 2-O ribose methyltransferase substrate binding
PHA accumulation regulator DNA-binding N-terminal
Large ribosomal subunit protein uL15/eL18
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Moybdenum cofactor oxidoreductase dimerisation
Carbamoyl-phosphate synthase small subunit N-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
C4-dicarboxylate ABC transporter substrate-binding protein
Resolvase/invertase-type recombinase catalytic
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Small ribosomal subunit protein uS4 N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA adenine methylase transferase N-terminal
DNA mismatch repair proteins mutS family
Inosine/uridine-preferring nucleoside hydrolase
Membrane insertase YidC/Oxa/ALB C-terminal
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Pyrimidine nucleoside phosphorylase C-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Helix-hairpin-helix DNA-binding motif class 1
Nitrite/Sulfite reductase ferredoxin-like
Large ribosomal subunit protein uL6 alpha-beta
Essential for prephenate dehydratase activity
Phage terminase large subunit N-terminal
Chromosomal replication initiator protein DnaA
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Seems to be a necessary countercharge to the potassium cations
Cytochrome c-552/DMSO reductase-like haem-binding
Aminoacyl-tRNA synthetase class I anticodon-binding
Important for interaction with partner proteins
Putative regulatory protein FmdB Zinc ribbon
Molybdopterin cofactor biosynthesis C (MoaC)
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Transcription regulator AsnC/Lrp ligand binding
ABC transporter substrate-binding protein