Type VII secretion system protein EssD-like
Type II secretion system protein GspG C-terminal
Pseudouridine synthase I TruA alpha/beta
3-keto-disaccharide hydrolase domain-containing protein
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Carbamoyl-phosphate synthase small subunit N-terminal
Bacterial type II secretion system protein E
Schiff-base intermediate with substrate; via pyruvic acid
Phosphatidic acid phosphatase type 2/haloperoxidase
Pyruvate phosphate dikinase AMP/ATP-binding
Aminoacyl-transfer RNA synthetases class-II family profile
Major facilitator superfamily (MFS) profile
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Transposase IS204/IS1001/IS1096/IS1165 DDE
Transposase IS204/IS1001/IS1096/IS1165 helix-turn-helix
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
SUF system FeS cluster assembly SufBD N-terminal
Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Anaphase-promoting complex subunit 4-like WD40
Resolvase/invertase-type recombinase catalytic
N-sulphoglucosamine sulphohydrolase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Gfo/Idh/MocA-like oxidoreductase bacterial type C-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Anthranilate synthase component I N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Flagellar basal body rod protein N-terminal
PhoD-like phosphatase metallophosphatase
Methylene-tetrahydromethanopterin dehydrogenase N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Glycosyltransferase subfamily 4-like N-terminal
Membrane fusion protein biotin-lipoyl like
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Alpha-glycerophosphate oxidase C-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Pyruvate dehydrogenase E1 component middle
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Inosine/uridine-preferring nucleoside hydrolase
Cytochrome C biogenesis protein transmembrane
Thiol:disulfide interchange protein DsbD N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Flagellar motor switch protein FliN-like C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Cytochrome b/b6 N-terminal region profile
Phosphoribosylformylglycinamidine synthase linker
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Polypeptide-transport-associated ShlB-type
N,N-dimethylformamidase beta subunit-like C-terminal
PEP-CTERM protein-sorting domain-containing protein
Aconitase A/isopropylmalate dehydratase small subunit swivel
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Carboxypeptidase regulatory-like domain-containing protein
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
Prepilin type IV endopeptidase peptidase
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
NADH:ubiquinone oxidoreductase 30kDa subunit
S-adenosyl-L-homocysteine hydrolase NAD binding
Ribose-phosphate pyrophosphokinase N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Polymerase/histidinol phosphatase N-terminal
Transposase IS116/IS110/IS902 C-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
RND efflux pump membrane fusion protein barrel-sandwich
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Positions MEP for the nucleophilic attack
Acyl-CoA dehydrogenase/oxidase C-terminal
Important for beta-aspartyl-AMP intermediate formation
Nitrite/Sulfite reductase ferredoxin-like
Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Gfo/Idh/MocA-like oxidoreductase C-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Large ribosomal subunit protein uL2 C-terminal
Chromosomal replication initiator DnaA C-terminal
6-phosphogluconate dehydrogenase C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Peptidase MA-like domain-containing protein
Pyridoxamine 5'-phosphate oxidase Alr4036 family FMN-binding
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Membrane insertase YidC/Oxa/ALB C-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Proton acceptor; for glutaminase activity
Prokaryotic-type class I peptide chain release factors
Cysteine sulfenic acid (-SOH) intermediate
Neutral/alkaline non-lysosomal ceramidase N-terminal
Peptide methionine sulphoxide reductase MsrA
Putative Flp pilus-assembly TadG-like N-terminal
Cytochrome b/b6 C-terminal region profile
Schiff-base intermediate with acetaldehyde
Methylguanine DNA methyltransferase ribonuclease-like
Gp5/Type VI secretion system Vgr protein OB-fold
Sodium/calcium exchanger membrane region
Alanyl-transfer RNA synthetases family profile
Flagella basal body P-ring formation protein FlgA C-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Glycine cleavage T-protein C-terminal barrel
Flagellar basal-body/hook protein C-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Small ribosomal subunit protein uS4 N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Important for interaction with partner proteins
Type I restriction enzyme R protein N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Superoxide dismutase copper/zinc binding
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Periplasmic copper-binding protein NosD beta helix
Right handed beta helix domain-containing protein
SMP-30/Gluconolactonase/LRE-like region domain-containing protein
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
von Hippel-Lindau disease tumour suppressor beta
Beta-xylosidase C-terminal Concanavalin A-like domain-containing protein
General stress protein FMN-binding split barrel
Polysaccharide biosynthesis protein CapD-like
Rhamnogalacturonan lyase domain-containing protein
Glycosyl transferase family 3 N-terminal
Bacterial type II/III secretion system short domain protein
Translation elongation factor EFTs/EF1B dimerisation
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Tryptophan synthase beta chain-like PALP
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Glycosyl hydrolase-like 10 domain-containing protein
Cellulose-binding Sde182 nucleoside hydrolase-like
Cellulose-binding Sde182 nucleoside hydrolase-like domain-containing protein
DNA-directed DNA polymerase family A palm
5-glutamyl coenzyme A thioester intermediate
Calcineurin-like phosphoesterase C-terminal
Calcineurin-like phosphoesterase N-terminal
Neutral/alkaline non-lysosomal ceramidase
Peptidase C-terminal archaeal/bacterial domain-containing protein
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Phosphomannose isomerase type I catalytic
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr C-terminal
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr N-terminal
Gamma-glutamylcyclotransferase AIG2-like
Involved in ionization of N3 of dUMP, leading to its activation
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Gamma-butyrobetaine hydroxylase-like N-terminal
Urease accessory protein UreH-like transmembrane
Protein-L-isoaspartate O-methyltransferase
LamG-like jellyroll fold domain-containing protein
DNA replication/recombination mediator RecO N-terminal
Thiamine pyrophosphate enzyme TPP-binding
Release factor glutamine methyltransferase N-terminal
Na+/H+ antiporter MnhB subunit-related protein
Endoribonuclease L-PSP/chorismate mutase-like
Glucose-methanol-choline oxidoreductase C-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Polysaccharide biosynthesis protein C-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
DNA mismatch repair proteins mutS family
DNA/pantothenate metabolism flavoprotein C-terminal
Influences the redox potential of the prosthetic heme and FAD groups
Involved in heme-bound ligand stabilization and O-O bond activation
Large ribosomal subunit protein uL6 alpha-beta
Phosphatidylglycerol lysyltransferase C-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Flagellar assembly protein FliH/Type III secretion system HrpE
UDP N-acetylglucosamine O-acyltransferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Putative regulatory protein FmdB Zinc ribbon
Large ribosomal subunit protein uL15/eL18
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Outer membrane lipoprotein-sorting protein
Heme-copper oxidase subunit III family profile
Xylose isomerase-like TIM barrel domain-containing protein
Alpha-amylase/4-alpha-glucanotransferase C-terminal
Alpha-amylase/4-alpha-glucanotransferase central
Glycoside hydrolase family 57 N-terminal
Glycosyl hydrolase family 98 putative carbohydrate-binding module
Glucosamine/galactosamine-6-phosphate isomerase
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
TRAP C4-dicarboxylate transport system permease DctM subunit
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Microcystin LR degradation protein MlrC C-terminal
Microcystin LR degradation protein MlrC N-terminal
Type I restriction enzyme HindI endonuclease subunit-like C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Phosphotransferase system enzyme I N-terminal
Plays an important role in substrate specificity
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Glycosyltransferase RgtA/B/C/D-like domain-containing protein
Glutamate synthase alpha subunit C-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Pyrimidine nucleoside phosphorylase C-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Gly-cisPro motif, important for rejection of L-amino acids
Regulator of nucleoside diphosphate kinase N-terminal
Transcription elongation factor GreA/GreB C-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Alpha glucuronidase N-terminal domain-containing protein
Aminoacyl-tRNA synthetase class I anticodon-binding
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Mannose-6-phosphate isomerase type II C-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Reversibly protonated during proton transport
tRNA pseudouridylate synthase B C-terminal
ATP-dependent DNA helicase RecG C-terminal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Polysaccharide chain length determinant N-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG middle
Transcription elongation factor GreA/GreB N-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Penicillin-binding protein transpeptidase
RNA binding; important for wobble base 34 recognition
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Type I restriction modification DNA specificity
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Bacterial transcription activator effector binding
RNA 2-O ribose methyltransferase substrate binding
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
ABC-type uncharacterised transport system
3-beta hydroxysteroid dehydrogenase/isomerase
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Beta-xylosidase C-terminal Concanavalin A-like
Peptidase M1 membrane alanine aminopeptidase
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Arginine decarboxylase C-terminal helical
Mechanosensitive ion channel inner membrane
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)