Electron transfer flavoprotein alpha/beta-subunit N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Erythronate-4-phosphate dehydrogenase dimerisation
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Pyrroline-5-carboxylate reductase catalytic N-terminal
Large ribosomal subunit protein uL15/eL18
Chromosomal replication initiator DnaA C-terminal
TonB-dependent receptor-like beta-barrel
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Tryptophan synthase beta chain-like PALP
Virulence factor membrane-bound polymerase C-terminal
Prokaryotic-type class I peptide chain release factors
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Aminoacyl-transfer RNA synthetases class-II family profile
Transposase IS204/IS1001/IS1096/IS1165 DDE
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
Carbamoyl-phosphate synthase small subunit N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Type II secretion system protein GspG C-terminal
Polysaccharide chain length determinant N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Bacterial type II secretion system protein E
Adaptive response protein AidB N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Transferrin-binding protein-like solute binding protein
Reversibly protonated during proton transport
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
PhoD-like phosphatase metallophosphatase
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Thiol:disulfide interchange protein DsbG
Cytochrome b561 bacterial/Ni-hydrogenase
Major facilitator superfamily (MFS) profile
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Phosphatidic acid phosphatase type 2/haloperoxidase
Schiff-base intermediate with substrate; via pyruvic acid
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Aconitase A/isopropylmalate dehydratase small subunit swivel
Membrane fusion protein biotin-lipoyl like
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Solute-binding protein family 3/N-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Acyl-CoA dehydrogenase C-terminal bacterial-type
Anthranilate synthase component I N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Outer-membrane lipoprotein carrier protein
Regulator of nucleoside diphosphate kinase N-terminal
Transcription elongation factor GreA/GreB C-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Na+/H+ antiporter MnhB subunit-related protein
Molybdenum ABC transporter substrate-binding protein
Glycosyl transferase family 3 N-terminal
DNA mismatch repair proteins mutS family
SMODS-associated and fused to various effectors
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Polymerase/histidinol phosphatase N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Nitrite/Sulfite reductase ferredoxin-like
Pseudouridine synthase I TruA alpha/beta
Quercetin 2,3-dioxygenase C-terminal cupin
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Penicillin-binding protein transpeptidase
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Outer membrane protein assembly factor BamD
Putative exodeoxyribonuclease 8 PDDEXK-like
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Peptidase M17 leucyl aminopeptidase N-terminal
NIF system FeS cluster assembly NifU N-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Glycine zipper 2TM domain-containing protein
Soluble ligand binding domain-containing protein
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Small ribosomal subunit protein uS4 N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
NAD(P) transhydrogenase alpha subunit C-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Acyl-ester intermediate; for transpeptidase activity
Proton donor; for transglycosylase activity
Transposase IS204/IS1001/IS1096/IS1165 helix-turn-helix
NADH:flavin oxidoreductase/NADH oxidase N-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Essential for prephenate dehydratase activity
Large ribosomal subunit protein bL25 L25
RND efflux pump membrane fusion protein barrel-sandwich
Transcription elongation factor GreA/GreB N-terminal
Important for substrate binding and specificity
Important for interaction with partner proteins
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Required for zinc-mediated homotetramerization and catalytic activity
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Survival protein SurE-like phosphatase/nucleotidase
RNA binding; important for wobble base 34 recognition
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Type III restriction enzyme C-terminal endonuclease
Resolvase/invertase-type recombinase catalytic
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Outer membrane protein assembly factor BamA
Putative auto-transporter adhesin head GIN
UDP N-acetylglucosamine O-acyltransferase C-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
DNA-directed DNA polymerase family A palm
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Thymidylate synthase/dCMP hydroxymethylase
RNA 2-O ribose methyltransferase substrate binding
Large ribosomal subunit protein uL6 alpha-beta
Peptide methionine sulphoxide reductase MsrA
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Alpha-glycerophosphate oxidase C-terminal
Heme-copper oxidase subunit III family profile
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
RlpA-like protein double-psi beta-barrel
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Tellurite resistance methyltransferase TehB-like
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Spore coat protein U domain-containing protein
Meso-diaminopimelate D-dehydrogenase C-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Plays an important role in substrate specificity
Aminoacyl-tRNA synthetase class I anticodon-binding
Membrane insertase YidC/Oxa/ALB C-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Alpha-D-phosphohexomutase alpha/beta/alpha
Chromosomal replication initiator protein DnaA
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Defence against restriction A N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Organic solvent tolerance-like N-terminal
Important for autoinhibition of adenylyltransferase activity
Prepilin type IV endopeptidase peptidase
Superoxide dismutase copper/zinc binding
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Polysaccharide biosynthesis protein CapD-like
NIF system FeS cluster assembly NifU C-terminal
Thiol:disulfide interchange protein DsbD N-terminal
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Methylguanine DNA methyltransferase ribonuclease-like
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
N-end rule aminoacyl transferase C-terminal
Disulphide bond isomerase DsbC/G N-terminal
Phosphoethanolamine transferase N-terminal
Large ribosomal subunit protein uL2 C-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Pyrroline-5-carboxylate reductase dimerisation
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
SGNH hydrolase-type esterase domain-containing protein
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Interaction with polymerase core subunit RpoC
DNA replication/recombination mediator RecO N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
Pyruvate dehydrogenase E1 component middle
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Beta-lactamase hydrolase-like protein phosphatase-like
Translation elongation factor P/YeiP central
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Tetrahydrodipicolinate-N-succinyltransferase chain A
Involved in tetramerization or stability of the tetramer
Gly-cisPro motif, important for rejection of L-amino acids
O-(3'-phospho-DNA)-tyrosine intermediate
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Bacterial Ig-like domain-containing protein
Could be important to modulate the pK values of the two catalytic cysteine residues
Proton acceptor; for glutaminase activity
Electron transfer via tryptophanyl radical
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Lipopolysaccharide export system protein LptA
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Pyruvate phosphate dikinase AMP/ATP-binding
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Type 4 fimbrial biogenesis protein PilX N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Release factor glutamine methyltransferase N-terminal