Photosynthesis system II assembly factor Ycf48/Hcf136-like
Photosynthesis system II assembly factor Ycf48/Hcf136-like domain-containing protein
Electron transfer via tryptophanyl radical
Solute-binding protein family 3/N-terminal domain-containing protein
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Flagellar basal body rod protein N-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Prokaryotic-type class I peptide chain release factors
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
PEP-CTERM sorting domain-containing protein
Transporter substrate-binding domain-containing protein
Urease accessory protein UreH-like transmembrane
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Ribose-phosphate pyrophosphokinase N-terminal
TonB-dependent receptor-like beta-barrel
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Survival protein SurE-like phosphatase/nucleotidase
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Chitobiase/beta-hexosaminidases N-terminal
Two-component system QseEF-associated lipoprotein QseG
Aconitase A/isopropylmalate dehydratase small subunit swivel
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Sodium/calcium exchanger membrane region
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Interaction with polymerase core subunit RpoC
Pesticidal crystal protein Cry22Aa Ig-like
Peptidase S9 prolyl oligopeptidase catalytic
Bacterial type II secretion system protein E
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Erythronate-4-phosphate dehydrogenase dimerisation
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Major facilitator superfamily (MFS) profile
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Putative beta-barrel assembly-enhancing protease
Flagellar basal-body/hook protein C-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
UDP N-acetylglucosamine O-acyltransferase C-terminal
Polysaccharide biosynthesis protein CapD-like
Abortive infection protein-like C-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Large ribosomal subunit protein uL15/eL18
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-110)
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Tryptophan synthase beta chain-like PALP
UDP-glucose/GDP-mannose dehydrogenase C-terminal
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Extracellular exo-alpha-(1->5)-L-arabinofuranosidase
Glucosamine/galactosamine-6-phosphate isomerase
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
NIF system FeS cluster assembly NifU C-terminal
ABC-type uncharacterised transport system
ABC transporter substrate-binding protein
Extracellular endo-alpha-(1->5)-L-arabinanase C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Non-canonical purine NTP phosphatase/PRRC1
Proline utilization A proline dehydrogenase N-terminal
Flagellar assembly protein T N-terminal domain-containing protein
Phosphatidic acid phosphatase type 2/haloperoxidase
Histidine-specific methyltransferase SAM-dependent
Positions MEP for the nucleophilic attack
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
O-(5'-phospho-DNA)-tyrosine intermediate
Flagellar Assembly Protein A N-terminal region
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Aminoacyl-transfer RNA synthetases class-II family profile
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Reversibly protonated during proton transport
Toxin co-regulated pilus biosynthesis protein Q C-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Biopterin-dependent aromatic amino acid hydroxylase family profile
Glycosyltransferase subfamily 4-like N-terminal
Polymerase/histidinol phosphatase N-terminal
Required for zinc-mediated homotetramerization and catalytic activity
Arginine decarboxylase C-terminal helical
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Solute-binding protein family 3/N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
RNA polymerase sigma factor 70 region 4 type 2
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
DNA polymerase III subunit delta C-terminal
Glycoside hydrolase GH146 substrate-binding
Inosine/uridine-preferring nucleoside hydrolase
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Chromosomal replication initiator protein DnaA
Sodium symporter small subunit predicted
Interacts with tRNA; defines subfamily-specific binding signature
Outer membrane protein assembly factor BamA
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
TRAP C4-dicarboxylate transport system permease DctM subunit
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
RNA 2-O ribose methyltransferase substrate binding
Could be important to modulate the pK values of the two catalytic cysteine residues
Sugar fermentation stimulation protein C-terminal
Prepilin type IV endopeptidase peptidase
Peptide methionine sulphoxide reductase MsrA
6-phosphogluconate dehydrogenase C-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Exonuclease VII large subunit C-terminal
DNA mismatch repair MutH/Type II restriction enzyme Sau3AI
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Aminoacyl-tRNA synthetase class I anticodon-binding
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Curli production assembly/transport component CsgG
N-end rule aminoacyl transferase C-terminal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Transposon Tn7 transposition protein TnsD C-terminal
Methylguanine DNA methyltransferase ribonuclease-like
Mannose-6-phosphate isomerase type II C-terminal
Membrane fusion protein biotin-lipoyl like
Type II secretion system protein GspG C-terminal
Penicillin-binding protein transpeptidase
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
Ribosomal RNA adenine methylase transferase N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Glycosyltransferase 2-like prokaryotic type
Resolvase/invertase-type recombinase catalytic
Thymidylate synthase/dCMP hydroxymethylase
Membrane-bound lytic murein transglycosylase F
Could play a key role in the communication between the regulatory and the substrate sites
RNA binding; important for wobble base 34 recognition
Acyl-CoA dehydrogenase C-terminal bacterial-type
Polysaccharide chain length determinant N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Release factor glutamine methyltransferase N-terminal
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Flagellar hook-length control protein-like C-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Glutathionylspermidine synthase pre-ATP-grasp-like
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Translation elongation factor P/YeiP central
Thiamin/hydroxymethyl pyrimidine-binding YkoF putative
DNA replication/recombination mediator RecO N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Restriction endonuclease type II EcoRII C-terminal
Organic solvent tolerance-like N-terminal
SUF system FeS cluster assembly SufBD N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Plays an important role in discriminating NADH against NADPH
Flagellar assembly protein FliH/Type III secretion system HrpE
Restriction system protein Mrr-like N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
DNA-directed DNA polymerase family A palm
Outer membrane protein assembly factor BamB
Poly-beta-hydroxybutyrate polymerase N-terminal
High potential iron-sulfur proteins family profile
Important for beta-aspartyl-AMP intermediate formation
Bacterial virulence factor lipase N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
6-hydroxymethylpterin diphosphokinase MptE-like
Glycoside hydrolase family 13 N-terminal
Glycine cleavage T-protein C-terminal barrel
Involved in allosteric activation by GTP
Glycosyl-hydrolase 97 C-terminal oligomerisation
Cysteine sulfenic acid (-SOH) intermediate
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Type II secretion system protein GspC N-terminal
ABC-type transport auxiliary lipoprotein component
Capsule biosynthesis GfcC-like C-terminal
Capsule biosynthesis GfcC-like N-terminal
General stress protein FMN-binding split barrel
Saccharopine dehydrogenase-like C-terminal
GlyGly-CTERM sorting domain-containing protein
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Subtilisin-like protease fibronectin type-III
Alanyl-transfer RNA synthetases family profile
Type I restriction modification DNA specificity
Important for interaction with partner proteins
Type II secretion system protein GspI C-terminal
Flagellar motor switch protein FliN-like C-terminal
Transglutaminase domain-containing protein
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Anthranilate synthase component I N-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Endonuclease/exonuclease/phosphatase domain-containing protein
Small ribosomal subunit protein uS4 N-terminal
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Cytochrome c-type biogenesis protein CcmF C-terminal
Heme-copper oxidase subunit III family profile
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Pyruvate phosphate dikinase AMP/ATP-binding
Type III secretion system flagellar brake protein YcgR PilZN
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Bacterial OB-fold domain-containing protein
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
RNA methyltransferase SpoU/TrmH type C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Large ribosomal subunit protein uL2 C-terminal
Transglycosylase SLT domain-containing protein
NAD(P) transhydrogenase alpha subunit C-terminal
Phosphoethanolamine transferase N-terminal
PHA accumulation regulator DNA-binding N-terminal
Pseudouridine synthase I TruA alpha/beta
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Ricin B lectin domain-containing protein
Glycosyl hydrolase family 30 beta sandwich
Membrane insertase YidC/Oxa/ALB C-terminal
Conserved virulence factor B-like winged helix
Carbamoyl-phosphate synthase small subunit N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Appears to be important in orienting the phosphate for catalysis
Negative modulator of initiation of replication SeqA N-terminal
Replication modulator SeqA C-terminal DNA-binding
D-galactarate/Altronate dehydratase C-terminal
Proton acceptor; for glutaminase activity
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Transposase IS116/IS110/IS902 C-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Pyruvate dehydrogenase E1 component middle
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Magnesium transporter MgtE intracellular
YbaK/aminoacyl-tRNA synthetase-associated
Shikimate dehydrogenase substrate binding N-terminal
Glycosyl transferase family 3 N-terminal
Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal
Lipopolysaccharide export system protein LptA
DNA mismatch repair proteins mutS family
Large ribosomal subunit protein uL6 alpha-beta
Important for substrate binding and specificity
Tetrahydrodipicolinate-N-succinyltransferase chain A
Threonine/serine exporter-like N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Glycoside hydrolase family 42 N-terminal
Plays an important role in substrate specificity
Acyl-ester intermediate; for transpeptidase activity
Proton donor; for transglycosylase activity
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Antitoxin Xre/MbcA/ParS-like toxin-binding
Chromosomal replication initiator DnaA C-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Outer-membrane lipoprotein carrier protein