Ribosomal RNA small subunit methyltransferase E methyltransferase
Ribose-phosphate pyrophosphokinase N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Antitoxin Xre/MbcA/ParS-like toxin-binding
Major facilitator superfamily (MFS) profile
Aminoacyl-transfer RNA synthetases class-II family profile
FAD-dependent oxidoreductase 2 FAD binding
Solute-binding protein family 3/N-terminal
Tryptophan synthase beta chain-like PALP
Membrane fusion protein biotin-lipoyl like
Poly-beta-hydroxybutyrate polymerase N-terminal
Bacterial type II secretion system protein E
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
NADH:flavin oxidoreductase/NADH oxidase N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Transposase IS116/IS110/IS902 C-terminal
ABC-type glycine betaine transport system substrate-binding
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
RNA polymerase sigma factor 70 region 4 type 2
Glycine cleavage T-protein C-terminal barrel
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Sodium/calcium exchanger membrane region
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Rap1a immunity protein domain-containing protein
UDP N-acetylglucosamine O-acyltransferase C-terminal
Inosine/uridine-preferring nucleoside hydrolase
Type III restriction enzyme C-terminal endonuclease
Glycosyl transferase family 3 N-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
Glutathionylspermidine synthase pre-ATP-grasp-like
Reversibly protonated during proton transport
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Penicillin-binding protein transpeptidase
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
N-end rule aminoacyl transferase C-terminal
Polysaccharide chain length determinant N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Large ribosomal subunit protein uL2 C-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Prepilin type IV endopeptidase peptidase
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Prokaryotic-type class I peptide chain release factors
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
TonB-dependent receptor-like beta-barrel
Integral membrane protein YccS N-terminal
Alginate biosynthesis protein AlgX C-terminal carbohydrate-binding module
O-(3'-phospho-DNA)-tyrosine intermediate
Type VI secretion system IcmF C-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Urease accessory protein UreH-like transmembrane
Inner membrane protein YgaP-like transmembrane
Cob(I)alamin adenosyltransferase N-terminal
L-seryl-tRNA selenium transferase N-terminal
Siroheme decarboxylase AsnC-like ligand binding
Positions MEP for the nucleophilic attack
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Bacteriophage N4 adsorption protein A C-terminal
Glycine zipper 2TM domain-containing protein
LssY-like C-terminal domain-containing protein
PHA accumulation regulator DNA-binding N-terminal
Endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
Alpha-D-phosphohexomutase alpha/beta/alpha
Cytochrome b561 bacterial/Ni-hydrogenase
Ionotropic glutamate receptor C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
L,D-transpeptidase catalytic domain-containing protein
Bacterial transcription activator effector binding
Type II secretion system protein GspG C-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-91)
S-adenosylmethionine-dependent methyltransferase
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
YMGG-like Gly-zipper domain-containing protein
Molybdopterin cofactor biosynthesis C (MoaC)
Aspartate/homoserine dehydrogenase NAD-binding
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Peptide methionine sulfoxide reductase MsrA
Peptide methionine sulphoxide reductase MsrA
Water stress and hypersensitive response
Acyl-ester intermediate; for transpeptidase activity
Proton donor; for transglycosylase activity
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Shikimate dehydrogenase substrate binding N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Interaction with polymerase core subunit RpoC
Small ribosomal subunit protein uS4 N-terminal
Polymerase/histidinol phosphatase N-terminal
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Peptidase S9 prolyl oligopeptidase catalytic
Heme-copper oxidase subunit III family profile
NIF system FeS cluster assembly NifU C-terminal
Type 4 fimbrial biogenesis protein PilX N-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
Putative type VI secretion system Rhs element associated Vgr
May play a role in metal incorporation in vivo
May play a role in transmitting local conformational changes
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Carbamoyl-phosphate synthase small subunit N-terminal
DNA polymerase III subunit delta C-terminal
DNA-directed DNA polymerase family A palm
Organic solvent tolerance-like N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Pyridine nucleotide-disulphide oxidoreductase dimerisation
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Outer-membrane lipoprotein carrier protein
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Probable periplasmic serine endoprotease DegP-like
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Periplasmic nitrate reductase, electron transfer subunit
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Gamma-butyrobetaine hydroxylase-like N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Quinohemoprotein amine dehydrogenase gamma subunit structural
Electron transfer flavoprotein alpha subunit C-terminal
PhoD-like phosphatase metallophosphatase
TRAP C4-dicarboxylate transport system permease DctM subunit
Lysozyme inhibitor LprI N-terminal domain-containing protein
Thiol:disulfide interchange protein DsbD
Electron transfer via tryptophanyl radical
Mandelate racemase/muconate lactonizing enzyme C-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
6-phosphogluconate dehydrogenase C-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Flagella basal body P-ring formation protein FlgA
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
4'-phosphopantetheinyl transferase N-terminal
Type II secretion system protein GspE N-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Acetylserotonin O-methyltransferase dimerisation
Release factor glutamine methyltransferase N-terminal
Sporulation stage II protein D amidase enhancer LytB N-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Quinohemoprotein amine dehydrogenase alpha subunit
Quinohemoprotein amine dehydrogenase alpha subunit haem binding
RapA2 cadherin-like domain-containing protein
Metallopeptidase domain-containing protein
Outer membrane lipoprotein-sorting protein
Disulphide bond isomerase DsbC/G N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
PQQ-dependent catabolism-associated beta-propeller protein
Glycosyltransferase subfamily 4-like N-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
Transposase IS204/IS1001/IS1096/IS1165 DDE
Putative beta-barrel assembly-enhancing protease
2-oxoisovalerate dehydrogenase E1 alpha subunit N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
C-type lysozyme inhibitor domain-containing protein
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Guanylate kinase/L-type calcium channel beta subunit
Polysaccharide biosynthesis protein CapD-like
Helix-hairpin-helix DNA-binding motif class 1
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
Plays an important role in substrate specificity
Cytochrome C biogenesis protein transmembrane
Thiol:disulfide interchange protein DsbD N-terminal
Cation-transporting P-type ATPase N-terminal
Flagellar hook-length control protein-like C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Calcium/calmodulin-dependent protein kinase II association-domain
DNA polymerase III delta subunit C-terminal
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Glutamate synthase alpha subunit C-terminal
Curli production assembly/transport component CsgE
Phosphatidylglycerol lysyltransferase C-terminal
Periplasmic binding protein/LacI sugar binding
The binding site for the sugar molecule has not yet been established, but C-87 may be involved
Anthranilate synthase component I N-terminal
Outer membrane protein assembly factor BamA
Phosphoadenosine phosphosulphate reductase
Resolvase/invertase-type recombinase catalytic
Translation elongation factor P/YeiP central
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Chromosomal replication initiator protein DnaA
Large ribosomal subunit protein uL15/eL18
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Chromosomal replication initiator DnaA C-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Exonuclease VII large subunit C-terminal
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Lipoprotein YgdI/YgdR-like SH3-like domain-containing protein
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Mechanosensitive ion channel inner membrane
Biopterin-dependent aromatic amino acid hydroxylase family profile
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Photosynthesis system II assembly factor Ycf48/Hcf136-like domain-containing protein
Alpha-glycerophosphate oxidase C-terminal
Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase
Mannose-6-phosphate isomerase type II C-terminal
Glycoside hydrolase family 42 N-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
Peptidoglycan recognition protein family
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
Important for substrate binding and specificity
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Alkaline proteinase inhibitor/ Outer membrane lipoprotein Omp19
YbaK/aminoacyl-tRNA synthetase-associated
HicB-like antitoxin of toxin-antitoxin system
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Phosphatidic acid phosphatase type 2/haloperoxidase
Membrane insertase YidC/Oxa/ALB C-terminal
Isocitrate dehydrogenase kinase/phosphatase (AceK) kinase
Isocitrate dehydrogenase kinase/phosphatase (AceK) regulatory
Haem-binding uptake Tiki superfamily ChaN
ABC-type transport auxiliary lipoprotein component
Serine/threonine specific protein phosphatases
ATP synthase F1 complex delta/epsilon subunit N-terminal
Pyruvate dehydrogenase E1 component middle
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Required for dimer formation and molybdate binding
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
NAD(P) transhydrogenase alpha subunit C-terminal
Glucan biosynthesis periplasmic MdoG C-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Malonate/sodium symporter MadM subunit N-terminal
Peptidase M61 catalytic domain-containing protein
Lipoprotein SmpA/OmlA domain-containing protein
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Nucleophile; cysteine thiosulfonate intermediate
Holliday junction resolvasome, helicase subunit
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
ABC-type transport auxiliary lipoprotein component domain-containing protein
Large ribosomal subunit protein uL6 alpha-beta
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
SMP-30/Gluconolactonase/LRE-like region domain-containing protein
Translocation and assembly module subunit TamA
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
Water stress and hypersensitive response domain-containing protein
Polyribonucleotide nucleotidyltransferase
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Saccharopine dehydrogenase-like C-terminal
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Aromatic amino acid beta-eliminating lyase/threonine aldolase
NIF system FeS cluster assembly NifU N-terminal
Lipopolysaccharide export system protein LptA
Pyrroline-5-carboxylate reductase catalytic N-terminal
DNA mismatch repair proteins mutS family
DNA topoisomerase I catalytic core eukaryotic-type
Acetyl-CoA hydrolase/transferase C-terminal
Seems to be a necessary countercharge to the potassium cations
Flagellar motor switch protein FliN-like C-terminal
Lytic transglycosylase superhelical linker
Pseudouridine synthase I TruA alpha/beta
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Phosphocysteine intermediate; for EIIB activity
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Pyrroline-5-carboxylate reductase dimerisation
Outer-membrane lipoprotein Wza C-terminal
Outer membrane protein assembly factor BamB
Survival protein SurE-like phosphatase/nucleotidase
Alanyl-transfer RNA synthetases family profile
Ribosomal RNA small subunit methyltransferase E PUA-like
DNA replication/recombination mediator RecO N-terminal
Essential for prephenate dehydratase activity
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Erythronate-4-phosphate dehydrogenase dimerisation
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Endoribonuclease L-PSP/chorismate mutase-like
S-adenosyl-L-homocysteine hydrolase NAD binding
Solute-binding protein family 5 domain-containing protein
Nucleoside-specific outer membrane channel protein Tsx
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Regulator of nucleoside diphosphate kinase N-terminal
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Superoxide dismutase copper/zinc binding
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Sugar fermentation stimulation protein C-terminal
For 3-hydroxyacyl-CoA dehydrogenase activity
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Phosphoethanolamine transferase N-terminal
Quorum-sensing-regulated virulence factor
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
O-(phosphoribosyl dephospho-coenzyme A)serine
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase N-terminal
7 transmembrane helices usually fused to an inactive transglutaminase
Inactive transglutaminase fused to 7 transmembrane helices
Adaptive response protein AidB N-terminal
Arginine decarboxylase C-terminal helical
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Acyltransferase MbtK/IucB-like conserved
Interacts with tRNA; defines subfamily-specific binding signature
Putative regulatory protein FmdB Zinc ribbon
NADH:ubiquinone oxidoreductase 30kDa subunit
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Proline utilization A proline dehydrogenase N-terminal
Acyl-CoA dehydrogenase C-terminal bacterial-type
Important for interaction with partner proteins
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Ribosomal RNA adenine methylase transferase N-terminal
Cysteine sulfenic acid (-SOH) intermediate
RNA 2-O ribose methyltransferase substrate binding
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Gly-cisPro motif, important for rejection of L-amino acids
Flagellar assembly protein FliH/Type III secretion system HrpE
Involved in tetramerization or stability of the tetramer
Could be important to modulate the pK values of the two catalytic cysteine residues
Thymidylate synthase/dCMP hydroxymethylase
AB hydrolase-1 domain-containing protein
Glycine zipper domain-containing protein
Type III secretion system flagellar brake protein YcgR PilZN
Required for zinc-mediated homotetramerization and catalytic activity
Na+/H+ antiporter MnhB subunit-related protein
Bacterial bifunctional deaminase-reductase C-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker