Cation-transporting P-type ATPase N-terminal
Important for interaction with partner proteins
Glycosyl transferase family 3 N-terminal
Prokaryotic-type class I peptide chain release factors
Polysaccharide chain length determinant N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain-containing protein
Important for beta-aspartyl-AMP intermediate formation
ATP-dependent DNA helicase RecG C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Major facilitator superfamily (MFS) profile
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Alanyl-transfer RNA synthetases family profile
Phosphotransferase system enzyme I N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Shikimate dehydrogenase substrate binding N-terminal
Replication initiator protein A C-terminal
Penicillin-binding protein transpeptidase
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Surface layer protein A domain-containing protein
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Heat-inducible transcription repressor HrcA C-terminal
Tryptophan synthase beta chain-like PALP
Chromosomal replication initiator DnaA C-terminal
Solute-binding protein family 3/N-terminal
Large ribosomal subunit protein uL15/eL18
Gly-cisPro motif, important for rejection of L-amino acids
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Phage conserved hypothetical protein C-terminal
Type I restriction modification DNA specificity
Gfo/Idh/MocA-like oxidoreductase N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
6-phosphogluconate dehydrogenase C-terminal
X-Prolyl dipeptidyl aminopeptidase PepX N-terminal
Putative host cell surface-exposed lipoprotein Ltp-like HTH region
Single-stranded-DNA-specific exonuclease RecJ C-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Polymerase/histidinol phosphatase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
RNA binding; important for wobble base 34 recognition
RNA 2-O ribose methyltransferase substrate binding
Transposase IS204/IS1001/IS1096/IS1165 DDE
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
Type VII secretion system protein EssD-like
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Thiamin pyrophosphokinase thiamin-binding
Inosine/uridine-preferring nucleoside hydrolase
SUF system FeS cluster assembly SufBD N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Phosphocysteine intermediate; for EIIB activity
Bacterial type II secretion system protein E
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Small ribosomal subunit protein uS4 N-terminal
Ionotropic glutamate receptor C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Phage terminase large subunit C-terminal
Phage terminase large subunit N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Cell envelope-related transcriptional attenuator
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
ATP synthase F1 complex delta/epsilon subunit N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Alpha-glycerophosphate oxidase C-terminal
Glycosyltransferase subfamily 4-like N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Probable transposase IS891/IS1136/IS1341
Pseudouridine synthase I TruA alpha/beta
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Could play a key role in the communication between the regulatory and the substrate sites
Alpha-D-phosphohexomutase alpha/beta/alpha
Involved in proton transfer during cleavage
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Hydroxymethylglutaryl-coenzyme A synthase C-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
Transcriptional regulator TetR C-terminal Firmicutes type
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Polysaccharide biosynthesis protein C-terminal
Choloylglycine hydrolase/NAAA C-terminal
Septum formation inhibitor MinC C-terminal
DNA replication/recombination mediator RecO N-terminal
CobB/CobQ-like glutamine amidotransferase
N-acetylmuramoyl-L-alanine amidase domain-containing protein
Phosphomannose isomerase type I catalytic
Phosphoribosylformylglycinamidine synthase linker
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Interaction with polymerase core subunit RpoC
4Fe-4S ferredoxin-type domain-containing protein
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Plays an important role in substrate specificity
Peptidase M1 membrane alanine aminopeptidase
Peptidase S9 prolyl oligopeptidase catalytic
Helix-hairpin-helix DNA-binding motif class 1
Involved in allosteric activation by GTP
Nicking enzyme C-terminal middle helical
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Ribose-phosphate pyrophosphokinase N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Glucosamine/galactosamine-6-phosphate isomerase
Large ribosomal subunit protein uL2 C-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Sporulation transcription regulator WhiA N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
FAD-dependent oxidoreductase 2 FAD binding
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Thymidylate synthase/dCMP hydroxymethylase
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Aconitase A/isopropylmalate dehydratase small subunit swivel
Chromosomal replication initiator protein DnaA
Exonuclease VII large subunit C-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Phosphotransferase system EIIB component type 2/3
Gfo/Idh/MocA-like oxidoreductase C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
ABC-type glycine betaine transport system substrate-binding
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
DNA primase/polymerase bifunctional N-terminal
Peptide methionine sulphoxide reductase MsrA
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Ribosomal RNA adenine methylase transferase N-terminal
Important for autoinhibition of adenylyltransferase activity
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Translation elongation factor P/YeiP central
DNA-directed DNA polymerase family A palm
Phosphatidic acid phosphatase type 2/haloperoxidase
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Amino acid ABC transporter ATP-binding protein
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
O-(phosphoribosyl dephospho-coenzyme A)serine
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Large ribosomal subunit protein uL6 alpha-beta
Lyzozyme M1 (1,4-beta-N-acetylmuramidase)
Resolvase/invertase-type recombinase catalytic
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Alpha-L-rhamnosidase six-hairpin glycosidase
Bacterial alpha-L-rhamnosidase N-terminal
Reversibly protonated during proton transport
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
2,4-diaminopentanoate dehydrogenase C-terminal
NIF system FeS cluster assembly NifU N-terminal
Threonine/serine exporter-like N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Bacterial bifunctional deaminase-reductase C-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Terminase large subunit-like endonuclease
Gram-positive cocci surface proteins LPxTG
Gram-positive cocci surface proteins LPxTG domain-containing protein
DNA mismatch repair proteins mutS family
Signal recognition particle SRP54 helical bundle