Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Glycine cleavage T-protein C-terminal barrel
TonB-dependent receptor-like beta-barrel
Mannose-6-phosphate isomerase type II C-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Solute-binding protein family 3/N-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Major facilitator superfamily (MFS) profile
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Phosphatidylglycerol lysyltransferase C-terminal
Sugar fermentation stimulation protein C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Glycoside hydrolase family 42 N-terminal
AraC-type arabinose-binding/dimerisation
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
DNA replication/recombination mediator RecO N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Cysteine sulfenic acid (-SOH) intermediate
S-adenosylmethionine-dependent methyltransferase
O-(5'-phospho-DNA)-tyrosine intermediate
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Saccharopine dehydrogenase-like C-terminal
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-98)
Peptidase G2 IMC autoproteolytic cleavage
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Excalibur calcium-binding domain-containing protein
DnaJ homologue subfamily C member 28 conserved
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Penicillin-binding protein transpeptidase
Bacterial type II secretion system protein E
Cytochrome oxidase subunit II copper A binding
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
N-end rule aminoacyl transferase C-terminal
Prepilin type IV endopeptidase peptidase
Glucose-methanol-choline oxidoreductase N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Cytochrome b561 bacterial/Ni-hydrogenase
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Phenol hydroxylase C-terminal dimerisation
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Glycosyl transferase family 3 N-terminal
Pyrimidine nucleoside phosphorylase C-terminal
Plays an important role in substrate specificity
Transcription regulator AsnC/Lrp ligand binding
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Cobaltochelatase subunit CobS N-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Histidine phosphotransferase ChpT C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Thiamin pyrophosphokinase thiamin-binding
Membrane fusion protein biotin-lipoyl like
Glycosyl transferase family 28 C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
CobB/CobQ-like glutamine amidotransferase
RNA polymerase sigma factor 70 region 4 type 2
Cytochrome c-type biogenesis protein CcmF C-terminal
Glucan biosynthesis periplasmic MdoG C-terminal
Beta-lactamase hydrolase-like protein phosphatase-like
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Involved in allosteric activation by GTP
Flagellar motor switch protein FliN-like C-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Resolvase/invertase-type recombinase catalytic
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
ABC transporter substrate-binding protein PnrA-like
Alanyl-transfer RNA synthetases family profile
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Nitrite/Sulfite reductase ferredoxin-like
Molybdopterin cofactor biosynthesis C (MoaC)
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Release factor glutamine methyltransferase N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Phage terminase large subunit GpA ATPase
Terminase large subunit GpA endonuclease
TRAP C4-dicarboxylate transport system permease DctM subunit
Tryptophan synthase beta chain-like PALP
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Small ribosomal subunit protein uS4 N-terminal
SUF system FeS cluster assembly SufBD N-terminal
ABC-type Co2+ transport system, periplasmic component
Haem-binding uptake Tiki superfamily ChaN
Prokaryotic-type class I peptide chain release factors
Important for interaction with partner proteins
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Large ribosomal subunit protein uL15/eL18
ATP-dependent DNA helicase RecG C-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Type II secretion system protein TadB-like N-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Anthranilate synthase component I N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Alpha-glycerophosphate oxidase C-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Na+/H+ antiporter MnhB subunit-related protein
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Cytochrome c oxidase subunit IV bacterial aa3 type
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Heme-copper oxidase subunit III family profile
Large ribosomal subunit protein uL30-like ferredoxin-like fold
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Cytochrome oxidase subunit II transmembrane region profile
Electron transfer flavoprotein alpha/beta-subunit N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Carbamoyl-phosphate synthase small subunit N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Chromosomal replication initiator DnaA C-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Ionotropic glutamate receptor C-terminal
Glycosyltransferase family 28 N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
RNA 2-O ribose methyltransferase substrate binding
Flagella basal body P-ring formation protein FlgA
Polymerase/histidinol phosphatase N-terminal
Polysaccharide biosynthesis protein CapD-like
Aconitase A/isopropylmalate dehydratase small subunit swivel
General stress protein FMN-binding split barrel
Tat pathway signal sequence domain protein
Proton acceptor; for glutaminase activity
Pyridoxamine 5'-phosphate oxidase putative
Cob(I)alamin adenosyltransferase N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Cytochrome C biogenesis protein transmembrane
Large ribosomal subunit protein uL6 alpha-beta
Exonuclease VII large subunit C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Could be important to modulate the pK values of the two catalytic cysteine residues
Putative acyltransferase ACT14924-like acyltransferase
Tetrahydrodipicolinate-N-succinyltransferase chain A
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Ysc84 actin-binding domain-containing protein
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Translation elongation factor P/YeiP central
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Electron transfer via tryptophanyl radical
Interaction with polymerase core subunit RpoC
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Peptide methionine sulphoxide reductase MsrA
Pyruvate/ketoisovalerate oxidoreductase catalytic
DNA primase/polymerase bifunctional N-terminal
NIF system FeS cluster assembly NifU N-terminal
Aspartate/homoserine dehydrogenase NAD-binding
Ribose-phosphate pyrophosphokinase N-terminal
Survival protein SurE-like phosphatase/nucleotidase
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Thymidylate synthase/dCMP hydroxymethylase
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Poly-beta-hydroxybutyrate polymerase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Gp5/Type VI secretion system Vgr protein OB-fold
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
Acyl-CoA dehydrogenase N-terminal bacteria
4'-phosphopantetheinyl transferase N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Protocatechuate 3,4-dioxygenase beta subunit N-terminal
Putative Flp pilus-assembly TadG-like N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
DNA-directed DNA polymerase family A palm
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
DNA polymerase III beta sliding clamp C-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Thiol:disulfide interchange protein DsbD N-terminal
Inosine/uridine-preferring nucleoside hydrolase
Metallo-beta-lactamase domain-containing protein
Membrane insertase YidC/Oxa/ALB C-terminal
Helix-hairpin-helix DNA-binding motif class 1
Tip attachment protein J domain-containing protein
Moybdenum cofactor oxidoreductase dimerisation
Signal recognition particle SRP54 helical bundle
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Glucosamine/galactosamine-6-phosphate isomerase
Reversibly protonated during proton transport
L,D-transpeptidase catalytic domain-containing protein
Gly-cisPro motif, important for rejection of L-amino acids
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Type III restriction enzyme C-terminal endonuclease
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Large ribosomal subunit protein uL2 C-terminal
Sodium/calcium exchanger membrane region
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Plasmid replication protein C N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
PHA accumulation regulator DNA-binding N-terminal
TtsA-like Glycoside hydrolase family 108
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Ribonucleotide reductase large subunit N-terminal
Endoribonuclease L-PSP/chorismate mutase-like
Interacts with tRNA; defines subfamily-specific binding signature