Mannose-6-phosphate isomerase type II C-terminal
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Photosynthesis system II assembly factor Ycf48/Hcf136-like domain-containing protein
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Glucose-methanol-choline oxidoreductase N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
TRAP C4-dicarboxylate transport system permease DctM subunit
Mandelate racemase/muconate lactonizing enzyme C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Release factor glutamine methyltransferase N-terminal
Polysaccharide chain length determinant N-terminal
Protein-PII uridylyltransferase N-terminal
Tryptophan synthase beta chain-like PALP
DNA-directed DNA polymerase family A palm
Major facilitator superfamily (MFS) profile
Phosphoethanolamine transferase N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Poly-beta-hydroxybutyrate polymerase N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Type I restriction modification DNA specificity
Isocitrate dehydrogenase kinase/phosphatase (AceK) kinase
Isocitrate dehydrogenase kinase/phosphatase (AceK) regulatory
N-sulphoglucosamine sulphohydrolase C-terminal
Glycine zipper 2TM domain-containing protein
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Endolytic peptidoglycan transglycosylase RlpA
Aminoacyl-transfer RNA synthetases class-II family profile
Translation elongation factor P/YeiP central
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Flagellar motor switch protein FliN-like C-terminal
Glycosyltransferase subfamily 4-like N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Na+/H+ antiporter MnhB subunit-related protein
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Outer membrane protein assembly factor BamA
Cytochrome c-type biogenesis protein CcmF C-terminal
Moybdenum cofactor oxidoreductase dimerisation
Membrane fusion protein biotin-lipoyl like
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
High-affinity zinc uptake system protein ZnuA
Mechanosensitive ion channel inner membrane
Glucose-methanol-choline oxidoreductase C-terminal
Chromosomal replication initiator DnaA C-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Alpha-glycerophosphate oxidase C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
S-adenosylmethionine-dependent methyltransferase
Polysaccharide biosynthesis protein CapD-like
Blue (type 1) copper domain-containing protein
Flagellar assembly protein T N-terminal domain-containing protein
NAD(P) transhydrogenase alpha subunit C-terminal
Organic solvent tolerance-like N-terminal domain-containing protein
Microcystin LR degradation protein MlrC C-terminal
Microcystin LR degradation protein MlrC N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Plays an important role in substrate specificity
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Electron transfer via tryptophanyl radical
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Solute-binding protein family 3/N-terminal
Solute-binding protein family 3/N-terminal domain-containing protein
RND efflux pump membrane fusion protein barrel-sandwich
DNA mismatch repair proteins mutS family
Outer membrane protein assembly factor BamD
Peptide methionine sulfoxide reductase MsrA
Peptide methionine sulphoxide reductase MsrA
ABC transporter substrate-binding protein
Cob(I)alamin adenosyltransferase N-terminal
N-end rule aminoacyl transferase C-terminal
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
DNA polymerase III delta subunit C-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Translation elongation factor EFTs/EF1B dimerisation
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
ATP synthase F1 complex delta/epsilon subunit N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Large ribosomal subunit protein uL15/eL18
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Peptidase S8/S53 domain-containing protein
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Cytochrome b561 bacterial/Ni-hydrogenase
Plays an important role in discriminating NADH against NADPH
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
ABC-type glycine betaine transport system substrate-binding
Acyl-CoA dehydrogenase C-terminal bacterial-type
ABC transporter substrate-binding protein PnrA-like
Water stress and hypersensitive response
Water stress and hypersensitive response domain-containing protein
Glycine zipper domain-containing protein
Glycosyl transferase family 3 N-terminal
Nitrite/Sulfite reductase ferredoxin-like
N6 adenine-specific DNA methyltransferase N-terminal
Important for interaction with partner proteins
Polymerase/histidinol phosphatase N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Sodium symporter small subunit predicted
Small ribosomal subunit protein uS4 N-terminal
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
Electron transfer flavoprotein alpha/beta-subunit N-terminal
PEP-CTERM protein-sorting domain-containing protein
Thymidylate synthase/dCMP hydroxymethylase
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Exonuclease VII large subunit C-terminal
Interaction with polymerase core subunit RpoC
Pyruvate/ketoisovalerate oxidoreductase catalytic
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Important for beta-aspartyl-AMP intermediate formation
Alpha-D-phosphohexomutase alpha/beta/alpha
Disulphide bond isomerase DsbC/G N-terminal
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Type 4 fimbrial biogenesis protein PilX N-terminal
Contractile injection system tube protein N-terminal
Phosphogluconate dehydrogenase (decarboxylating) C-terminal
Urease accessory protein UreH-like transmembrane
Gly-cisPro motif, important for rejection of L-amino acids
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
TonB-dependent receptor-like beta-barrel
Flagellar assembly protein FliH/Type III secretion system HrpE
Acyl-ester intermediate; for transpeptidase activity
Penicillin-binding protein transpeptidase
Proton donor; for transglycosylase activity
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal domain-containing protein
Required for dimer formation and molybdate binding
Large ribosomal subunit protein uL6 alpha-beta
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Outer membrane lipoprotein-sorting protein
Activator of Hsp90 ATPase homologue 1-like C-terminal
Antitoxin Xre/MbcA/ParS-like toxin-binding
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Large ribosomal subunit protein uL2 C-terminal
Cobaltochelatase subunit CobS N-terminal
Glycine cleavage T-protein C-terminal barrel
Reversibly protonated during proton transport
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Shikimate dehydrogenase substrate binding N-terminal
Heme-copper oxidase subunit III family profile
Ribose-phosphate pyrophosphokinase N-terminal
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
YbaK/aminoacyl-tRNA synthetase-associated
Aromatic amino acid beta-eliminating lyase/threonine aldolase
UDP N-acetylglucosamine O-acyltransferase C-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Pyrroline-5-carboxylate reductase catalytic N-terminal
Cysteine sulfenic acid (-SOH) intermediate
Important for substrate binding and specificity
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
NIF system FeS cluster assembly NifU N-terminal
Phosphoadenosine phosphosulphate reductase
Virulence factor membrane-bound polymerase C-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Interacts with tRNA; defines subfamily-specific binding signature
Hydroxymethylglutaryl-coenzyme A synthase C-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Pseudouridine synthase I TruA alpha/beta
Peptidoglycan binding-like domain-containing protein
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Prepilin type IV endopeptidase peptidase
RNA 2-O ribose methyltransferase substrate binding
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
PQQ-dependent catabolism-associated beta-propeller protein
Ribosomal RNA small subunit methyltransferase E methyltransferase
Ribosomal RNA adenine methylase transferase N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Nucleophile; cysteine thiosulfonate intermediate
Type I restriction enzyme R protein N-terminal
NIF system FeS cluster assembly NifU C-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Co-chaperone HscB C-terminal oligomerisation
Gamma-butyrobetaine hydroxylase-like N-terminal
Quinohemoprotein amine dehydrogenase gamma subunit structural
Tellurite resistance methyltransferase TehB-like
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
Bacterial type II secretion system protein E
Pyruvate dehydrogenase E1 component middle
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Styrene monooxygenase StyA putative substrate binding
RNA polymerase sigma factor 70 region 4 type 2
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Survival protein SurE-like phosphatase/nucleotidase
Carbamoyl-phosphate synthase small subunit N-terminal
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Bacterial collagen-like protein middle domain-containing protein
2-oxoacid dehydrogenase acyltransferase catalytic
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
DNA-3-methyladenine glycosylase AlkA N-terminal
PhoD-like phosphatase metallophosphatase
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-103)
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Ribosomal RNA small subunit methyltransferase E PUA-like
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
Polypeptide-transport-associated ShlB-type
Polypeptide-transport-associated ShlB-type domain-containing protein
Quercetin 2,3-dioxygenase C-terminal cupin
Putative beta-barrel assembly-enhancing protease
TonB-dependent receptor plug domain-containing protein
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Gp5/Type VI secretion system Vgr protein OB-fold
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
NADH-rubredoxin oxidoreductase C-terminal
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Prokaryotic-type class I peptide chain release factors
Helix-hairpin-helix DNA-binding motif class 1
Flagellar hook-length control protein-like C-terminal
Twin-arginine translocation pathway signal
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
CobB/CobQ-like glutamine amidotransferase
DNA replication/recombination mediator RecO N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Transglycosylase SLT domain-containing protein
Sodium/calcium exchanger membrane region
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
May play a role in metal incorporation in vivo
May play a role in transmitting local conformational changes
5-glutamyl coenzyme A thioester intermediate
DNA polymerase III subunit delta C-terminal
Lysozyme inhibitor LprI N-terminal domain-containing protein
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Cytochrome oxidase subunit II copper A binding
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Alanyl-transfer RNA synthetases family profile
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Pyridoxamine 5'-phosphate oxidase putative
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold
RNA binding; important for wobble base 34 recognition
PHA accumulation regulator DNA-binding N-terminal
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Phosphatidylglycerol lysyltransferase C-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Anthranilate synthase component I N-terminal
Type III secretion system flagellar brake protein YcgR PilZN
Cytochrome oxidase subunit II transmembrane region profile
Alginate export domain-containing protein
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Outer membrane protein assembly factor BamB
Mechanosensitive ion channel protein MscS
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Translocation and assembly module subunit TamA
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Influences the redox potential of the prosthetic heme and FAD groups
Involved in heme-bound ligand stabilization and O-O bond activation
Divergent polysaccharide deacetylase family protein
Could be important to modulate the pK values of the two catalytic cysteine residues
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Peptidase C39-like domain-containing protein
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Resolvase/invertase-type recombinase catalytic
Sugar fermentation stimulation protein C-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
C4-dicarboxylate ABC transporter substrate-binding protein
Chromosomal replication initiator protein DnaA