FAD-dependent oxidoreductase 2 FAD binding
Large ribosomal subunit protein uL15/eL18
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Solute-binding protein family 3/N-terminal
Tetrahaem cytochrome domain-containing protein
YbaK/aminoacyl-tRNA synthetase-associated
Thiamine pyrophosphate enzyme TPP-binding
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
N6 adenine-specific DNA methyltransferase N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Interaction with polymerase core subunit RpoC
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Cytochrome b561 bacterial/Ni-hydrogenase
Translation elongation factor P/YeiP central
DNA replication/recombination mediator RecO N-terminal
HPr(Ser) kinase/phosphorylase N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Major facilitator superfamily (MFS) profile
Pseudouridine synthase I TruA alpha/beta
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Type I restriction modification DNA specificity
TonB-dependent receptor-like beta-barrel
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Membrane fusion protein biotin-lipoyl like
Phosphatidylglycerol lysyltransferase C-terminal
Outer membrane protein assembly factor BamC
Exonuclease VII large subunit C-terminal
Putative regulatory protein FmdB Zinc ribbon
Disulphide bond isomerase DsbC/G N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
FAD-dependent oxidoreductase 2 FAD binding domain-containing protein
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Reversibly protonated during proton transport
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
DNA-directed DNA polymerase family A palm
Alpha/beta hydrolase fold-3 domain-containing protein
ATP synthase F1 complex delta/epsilon subunit N-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
RNA binding; important for wobble base 34 recognition
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Important for autoinhibition of adenylyltransferase activity
Proton acceptor; for glutaminase activity
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Thioredoxin-like fold domain-containing protein
Formiminotransferase C-terminal subdomain
Formiminotransferase N-terminal subdomain
Aspartate/homoserine dehydrogenase NAD-binding
Required for zinc-mediated homotetramerization and catalytic activity
nitrite reductase (cytochrome; ammonia-forming)
ABC transporter substrate-binding protein PnrA-like
Outer membrane protein beta-barrel domain-containing protein
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Serine aminopeptidase S33 domain-containing protein
Ionotropic glutamate receptor C-terminal
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
NIF system FeS cluster assembly NifU N-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Aconitase A/isopropylmalate dehydratase small subunit swivel
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Positions MEP for the nucleophilic attack
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Bacterial type II secretion system protein E
Large ribosomal subunit protein uL2 C-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Ribonucleotide reductase large subunit C-terminal
Pyruvate/ketoisovalerate oxidoreductase catalytic
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
RND efflux pump membrane fusion protein barrel-sandwich
Chromosomal replication initiator protein DnaA
Essential for prephenate dehydratase activity
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Chromosomal replication initiator DnaA C-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Gamma-butyrobetaine hydroxylase-like N-terminal
Important for interaction with partner proteins
Polymerase/histidinol phosphatase N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Dinitrogenase iron-molybdenum cofactor biosynthesis
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Tryptophan synthase beta chain-like PALP
UDP N-acetylglucosamine O-acyltransferase C-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
Autotransporter domain-containing protein
Pyridoxamine 5'-phosphate oxidase family protein
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
RNA 2-O ribose methyltransferase substrate binding
Alpha-D-phosphohexomutase alpha/beta/alpha
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Ribosomal RNA adenine methylase transferase N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
ABC-type transport auxiliary lipoprotein component
Probable transposase IS891/IS1136/IS1341
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Flavodoxin-like domain-containing protein
DNA mismatch repair proteins mutS family
Bacterial OB-fold domain-containing protein
Glycosyltransferase subfamily 4-like N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Peptidase M20 dimerisation domain-containing protein
Bacteriophage T7 Gp4 DNA primase/helicase N-terminal
Transcription factor NikR nickel binding C-terminal
Periplasmic nitrate reductase, electron transfer subunit
Tetrahydrodipicolinate-N-succinyltransferase chain A
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Chitin-binding type-2 domain-containing protein
HupH hydrogenase expression protein C-terminal
Resolvase/invertase-type recombinase catalytic
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
CagE TrbE VirB component of type IV transporter system central
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Aldehyde ferredoxin oxidoreductase N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
O-(phosphoribosyl dephospho-coenzyme A)serine
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Bacterial bifunctional deaminase-reductase C-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Lipoprotein SmpA/OmlA domain-containing protein
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Interacts with tRNA; defines subfamily-specific binding signature
Alanyl-transfer RNA synthetases family profile
Thymidylate synthase/dCMP hydroxymethylase
HicB-like antitoxin of toxin-antitoxin system
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Ribose-phosphate pyrophosphokinase N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Gly-cisPro motif, important for rejection of L-amino acids
Molybdopterin cofactor biosynthesis C (MoaC)
Small ribosomal subunit protein uS4 N-terminal
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Survival protein SurE-like phosphatase/nucleotidase
Aminoacyl-tRNA synthetase class I anticodon-binding
Phosphotransferase system enzyme I N-terminal
SsuA/THI5-like domain-containing protein
Could be important to modulate the pK values of the two catalytic cysteine residues
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Plays an important role in substrate specificity
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Penicillin-binding protein transpeptidase
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal domain-containing protein
Type-F conjugative transfer system pilin assembly protein TrbC