TRAP C4-dicarboxylate transport system permease DctM subunit
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Glycosyltransferase subfamily 4-like N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Glycoside hydrolase family 42 N-terminal
Transposase IS204/IS1001/IS1096/IS1165 DDE
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
Major facilitator superfamily (MFS) profile
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Thiamin pyrophosphokinase thiamin-binding
Anthranilate synthase component I N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Alanyl-transfer RNA synthetases family profile
Molybdopterin cofactor biosynthesis C (MoaC)
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Ribosomally synthesized peptide with SipW-like signal peptide
Polysaccharide biosynthesis protein CapD-like
Phosphoribosylformylglycinamidine synthase linker
RNA polymerase sigma factor 70 region 4 type 2
ABC transporter substrate-binding protein PnrA-like
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Peptidase S9 prolyl oligopeptidase catalytic
Peptidoglycan hydrolase CwlO-like protein
Inosine/uridine-preferring nucleoside hydrolase
Methylene-tetrahydrofolate reductase C-terminal
Pseudouridine synthase I TruA alpha/beta
Schiff-base intermediate with dihydroxyacetone-P
O-(3'-phospho-DNA)-tyrosine intermediate
Positions MEP for the nucleophilic attack
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
F420-non-reducing hydrogenase iron-sulfur subunit D
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Prokaryotic-type class I peptide chain release factors
Interaction with polymerase core subunit RpoC
ATP-dependent DNA helicase RecG C-terminal
Polymerase/histidinol phosphatase N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Pyruvate/ketoisovalerate oxidoreductase catalytic
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Cell envelope-related transcriptional attenuator
S-adenosylmethionine-dependent methyltransferase
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
Gamma-glutamylcyclotransferase AIG2-like
DNA replication/recombination mediator RecO N-terminal
Penicillin-binding protein transpeptidase
Tryptophan synthase beta chain-like PALP
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Lantibiotic biosynthesis protein dehydration
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
Formylmethanofuran dehydrogenase subunit E
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Dipicolinate synthase subunit A N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Sporulation initiation factor Spo0A C-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Bacterial repeat domain-containing protein
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Could play a key role in the communication between the regulatory and the substrate sites
Prepilin type IV endopeptidase peptidase
Signal transduction histidine kinase internal region
Gram-positive cocci surface proteins LPxTG
LPXTG-motif cell wall-anchored protein/fimbrial isopeptide formation D2 family protein
ATPsynthase alpha/beta subunit N-terminal extension
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
FAD-dependent oxidoreductase 2 FAD binding
Pyridoxamine 5'-phosphate oxidase putative
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Putative exodeoxyribonuclease 8 PDDEXK-like
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Tricarboxylic transport membrane protein
Alpha-D-phosphohexomutase alpha/beta/alpha
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
ABC-type glycerol-3-phosphate transport system substrate-binding protein
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Plays an important role in substrate specificity
Resolvase/invertase-type recombinase catalytic
Gly-cisPro motif, important for rejection of L-amino acids
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Phosphoadenosine phosphosulphate reductase
Thymidylate synthase/dCMP hydroxymethylase
Ribosomal RNA adenine methylase transferase N-terminal
Meso-diaminopimelate D-dehydrogenase C-terminal
Gram-positive cocci surface proteins LPxTG domain-containing protein
Multiple sugar transport system substrate-binding protein
Aconitase A/isopropylmalate dehydratase small subunit swivel
Glucosamine/galactosamine-6-phosphate isomerase
Plays an important role in discriminating NADH against NADPH
Phosphatidylglycerol lysyltransferase C-terminal
6-phosphogluconate dehydrogenase C-terminal
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Threonine/serine exporter-like N-terminal
Prealbumin-like fold domain-containing protein
Ribose-phosphate pyrophosphokinase N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Polysaccharide chain length determinant N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Cation-transporting P-type ATPase N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Thiopeptide-type bacteriocin biosynthesis
RNA 2-O ribose methyltransferase substrate binding
Sporulation stage IV protein A C-terminal
Helix-hairpin-helix DNA-binding motif class 1
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
DNA mismatch repair MutH/Type II restriction enzyme Sau3AI
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Alpha-L-rhamnosidase six-hairpin glycosidase
Bacterial alpha-L-rhamnosidase N-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Bacterial bifunctional deaminase-reductase C-terminal
Peptidoglycan binding-like domain-containing protein
Exonuclease VII large subunit C-terminal
Glycoside hydrolase family 31 N-terminal
Aspartate/homoserine dehydrogenase NAD-binding
Sporulation transcription regulator WhiA N-terminal
Small ribosomal subunit protein uS4 N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Fe/B12 periplasmic-binding domain-containing protein
CO dehydrogenase/acetyl-CoA synthase delta subunit TIM barrel
YbaK/aminoacyl-tRNA synthetase-associated
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Alpha galactosidase C-terminal beta sandwich
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Methylaspartate ammonia-lyase C-terminal
Methylaspartate ammonia-lyase N-terminal
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Bacterial type II secretion system protein E
Aldehyde ferredoxin oxidoreductase N-terminal
O-(phosphoribosyl dephospho-coenzyme A)serine
CobB/CobQ-like glutamine amidotransferase
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Lacto-N-biose phosphorylase-like N-terminal TIM barrel
Could be important to modulate the pK values of the two catalytic cysteine residues
Aldouronate transport system substrate-binding protein
Stage III sporulation protein AA AAA+ ATPase
Lantibiotic immunity protein Spa1 C-terminal
Lantibiotic immunity protein Spa1 C-terminal domain-containing protein
Large ribosomal subunit protein bL9 C-terminal
Solute-binding protein family 3/N-terminal
Helix-hairpin-helix DNA-binding motif class 1 domain-containing protein
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
DNA-directed DNA polymerase family A palm
NIF system FeS cluster assembly NifU N-terminal
DNA mismatch repair proteins mutS family
Chromosomal replication initiator DnaA C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Important for substrate specificity; cannot use PPi as phosphoryl donor
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Putative aromatic acid exporter C-terminal
Large ribosomal subunit protein uL6 alpha-beta
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Sugar fermentation stimulation protein C-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Tripartite ATP-independent transporter DctP family solute receptor
Reversibly protonated during proton transport
Ribonucleotide reductase large subunit C-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Sodium/calcium exchanger membrane region
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Important for beta-aspartyl-AMP intermediate formation
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
O-(5'-phospho-DNA)-tyrosine intermediate
Mandelate racemase/muconate lactonizing enzyme C-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Large ribosomal subunit protein uL15/eL18
Bacterial transcription activator effector binding
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Inosine monophosphate cyclohydrolase-like
Helix-turn-helix conjugative transposon-like
Polysaccharide biosynthesis protein C-terminal
Alpha-L-glutamate ligase-related protein ATP-grasp
Translation elongation factor P/YeiP central
Raffinose/stachyose/melibiose transport system substrate-binding protein
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
CO dehydrogenase/acetyl-CoA synthase complex beta subunit C-terminal
Carbon monoxide dehydrogenase subunit alpha ,N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Lactose/L-arabinose transport system substrate-binding protein
Large ribosomal subunit protein uL2 C-terminal
Shikimate dehydrogenase substrate binding N-terminal
Transposase IS116/IS110/IS902 C-terminal
DNA polymerase III delta subunit C-terminal
Phosphotransferase system enzyme I N-terminal
Extracellular endo-alpha-(1->5)-L-arabinanase C-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Transcriptional regulator LacI/GalR-like sensor
Essential for prephenate dehydratase activity
Sporulation stage II protein D amidase enhancer LytB N-terminal
Schiff-base intermediate with acetaldehyde
Transcription regulator AsnC/Lrp ligand binding
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
NADH-rubredoxin oxidoreductase C-terminal
Proton acceptor; for glutaminase activity
Formiminotransferase C-terminal subdomain
Formiminotransferase N-terminal subdomain
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
D-galactose/methyl-galactoside binding periplasmic protein MglB
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Serine aminopeptidase S33 domain-containing protein
SsuA/THI5-like domain-containing protein
Carbamoyl-phosphate synthase small subunit N-terminal
Alternate signal-mediated exported protein
PrcB C-terminal domain-containing protein
Phosphogluconate dehydrogenase (decarboxylating) C-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Release factor glutamine methyltransferase N-terminal