RNA polymerase sigma factor 70 region 4 type 2
Transposase IS204/IS1001/IS1096/IS1165 DDE
TonB-dependent receptor-like beta-barrel
Putative beta-lactamase-inhibitor-like PepSY-like
Putative beta-lactamase-inhibitor-like PepSY-like domain-containing protein
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Alpha-N-acetylglucosaminidase C-terminal
Alpha-N-acetylglucosaminidase N-terminal
Alpha-N-acetylglucosaminidase tim-barrel
Pyrroline-5-carboxylate reductase catalytic N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Bacterial surface antigen (D15) domain-containing protein
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Outer membrane protein beta-barrel domain-containing protein
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Putative auto-transporter adhesin head GIN
Major facilitator superfamily (MFS) profile
Substrate import-associated zinc metallohydrolase lipoprotein
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
ATPsynthase alpha/beta subunit N-terminal extension
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Anthranilate synthase component I N-terminal
Alpha-L-rhamnosidase six-hairpin glycosidase
Bacterial alpha-L-rhamnosidase N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Pseudouridine synthase I TruA alpha/beta
Type I restriction enzyme R protein N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Menaquinone biosynthesis protein MenD middle
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Extracellular endo-alpha-(1->5)-L-arabinanase C-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Important for catalytic activity against all substrates
Important for catalytic activity against dermatan sulfate substrate
Beta-xylosidase C-terminal Concanavalin A-like
Fibronectin type-III domain-containing protein
Release factor glutamine methyltransferase N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Type II restriction enzyme and methyltransferase RM.Eco57I-like
NigD-like C-terminal beta sandwich domain-containing protein
Resolvase/invertase-type recombinase catalytic
DNA mismatch repair protein MutS-like N-terminal
Cell division protein FtsQ/DivIB C-terminal
Gylcosyl hydrolase 115 C-terminal domain-containing protein
N-sulphoglucosamine sulphohydrolase C-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Glycosyl-hydrolase 97 C-terminal oligomerisation
Tryptophan synthase beta chain-like PALP
Penicillin-binding protein transpeptidase
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
NADH:flavin oxidoreductase/NADH oxidase N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Aminoacyl-transfer RNA synthetases class-II family profile
Outer membrane insertion signal domain protein
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Glucosamine/galactosamine-6-phosphate isomerase
Glycosyl transferase family 3 N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
RNA 2-O ribose methyltransferase substrate binding
Membrane insertase YidC/Oxa/ALB C-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
SusD-like N-terminal domain-containing protein
Sporulation stage II protein D amidase enhancer LytB N-terminal
RNA binding; important for wobble base 34 recognition
Transposase IS116/IS110/IS902 C-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Phage terminase large subunit N-terminal
Essential for prephenate dehydratase activity
Type IX secretion system protein PorV domain-containing protein
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Alpha-glycerophosphate oxidase C-terminal
T9SS C-terminal target domain-containing protein
UDP N-acetylglucosamine O-acyltransferase C-terminal
Large ribosomal subunit protein uL15/eL18
Alpha-L-glutamate ligase-related protein ATP-grasp
Carbamoyl-phosphate synthase small subunit N-terminal
Schiff-base intermediate with acetaldehyde
Pyruvate phosphate dikinase AMP/ATP-binding
Glycosyltransferase subfamily 4-like N-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
N6 adenine-specific DNA methyltransferase N-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
Fibrobacter succinogenes major paralogous domain-containing protein
ATP-dependent DNA helicase RecG C-terminal
Meso-diaminopimelate D-dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Large ribosomal subunit protein uL6 alpha-beta
Inosine/uridine-preferring nucleoside hydrolase
Pyruvate/ketoisovalerate oxidoreductase catalytic
Gly-cisPro motif, important for rejection of L-amino acids
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Glycosyl hydrolase family 98 putative carbohydrate-binding module
Glycoside hydrolase family 5 domain-containing protein
Saccharopine dehydrogenase-like C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Conserved virulence factor B-like winged helix
Fimbrial subunit protein C-terminal domain-containing protein
Solute-binding protein family 3/N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Outer membrane protein transport protein (OMPP1/FadL/TodX)
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Gfo/Idh/MocA-like oxidoreductase bacterial type C-terminal
SusD/RagB family nutrient-binding outer membrane lipoprotein
Important for beta-aspartyl-AMP intermediate formation
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Polymerase/histidinol phosphatase N-terminal
Polysaccharide biosynthesis protein C-terminal
Large ribosomal subunit protein uL2 C-terminal
Phosphodiester glycosidase domain-containing protein
Signal transduction histidine kinase internal region
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Rhamnogalacturonan I lyase beta-sheet domain-containing protein
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Pyrroline-5-carboxylate reductase dimerisation
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Thymidylate synthase/dCMP hydroxymethylase
Lipocalin-like domain-containing protein
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Peptidase M43 pregnancy-associated plasma-A
Polysaccharide lyase family 8 C-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Glycoside hydrolase GH146 substrate-binding
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Prokaryotic-type class I peptide chain release factors
Type I restriction modification DNA specificity
Glycogen debranching enzyme bacterial and archaeal type N-terminal
DNA replication/recombination mediator RecO N-terminal
Survival protein SurE-like phosphatase/nucleotidase
Phosphatidic acid phosphatase type 2/haloperoxidase
Glycosyl hydrolases family 2 sugar binding
Important for autoinhibition of adenylyltransferase activity
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Organic solvent tolerance-like N-terminal
Polysaccharide chain length determinant N-terminal
Alanyl-transfer RNA synthetases family profile
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
SUF system FeS cluster assembly SufBD N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Helix-hairpin-helix DNA-binding motif class 1
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Phosphatidylglycerol lysyltransferase C-terminal
Peptidoglycan recognition protein family
Bacteroidetes PKD-like domain-containing protein
Shikimate dehydrogenase substrate binding N-terminal
Bacterial toxin RNase RnlA/LsoA N-terminal
Bacterial toxin RNase RnlA/LsoA N-terminal repeated
Alpha galactosidase C-terminal beta sandwich
Chitobiase/beta-hexosaminidases N-terminal
Chromosomal replication initiator DnaA C-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Ribosomal RNA adenine methylase transferase N-terminal
Glycosyl hydrolase family 30 beta sandwich
Proton acceptor; for glutaminase activity
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Phosphoadenosine phosphosulphate reductase
Replication-associated protein G2P N-terminal
Beta-hexosaminidase bacterial type N-terminal
Putative acyltransferase ACT14924-like acyltransferase
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
DNA mismatch repair proteins mutS family
Ribose-phosphate pyrophosphokinase N-terminal
Trigger factor ribosome-binding bacterial
Translation elongation factor P/YeiP central
Schiff-base intermediate with substrate; via pyruvic acid
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
ParB-related ThiF-related cassette protein E
Glycoside hydrolase family 42 N-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Positions MEP for the nucleophilic attack
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Glycoside hydrolase family 57 N-terminal
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Glycine cleavage T-protein C-terminal barrel
Glycoside hydrolase family 31 N-terminal
6-phosphogluconate dehydrogenase C-terminal
Arginine decarboxylase C-terminal helical
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
YbaK/aminoacyl-tRNA synthetase-associated
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
O-(3'-phospho-DNA)-tyrosine intermediate
Helix-hairpin-helix domain-containing protein
tRNA pseudouridylate synthase B C-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Carboxypeptidase-like regulatory domain-containing protein
Sodium/calcium exchanger membrane region
Pesticidal crystal protein Cry22Aa Ig-like
Small ribosomal subunit protein uS4 N-terminal
Phosphomannose isomerase type I catalytic
Cell wall-active antibiotics response LiaF-like C-terminal
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Cysteine sulfenic acid (-SOH) intermediate
Cation-transporting P-type ATPase N-terminal
Fibrobacter succinogenes major paralogous
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Exonuclease VII large subunit C-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Reversibly protonated during proton transport
Plays an important role in substrate specificity
Important for substrate specificity; cannot use PPi as phosphoryl donor
Membrane fusion protein biotin-lipoyl like
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
General stress protein FMN-binding split barrel
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
DNA-directed DNA polymerase family A palm
Threonine/serine exporter-like N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type