Probable transposase IS891/IS1136/IS1341
Tryptophan synthase beta chain-like PALP
HicB-like antitoxin of toxin-antitoxin system
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Na+-translocating membrane potential-generating system MpsC
Major facilitator superfamily (MFS) profile
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Positions MEP for the nucleophilic attack
Bacterial type II secretion system protein E
Opioid growth factor receptor (OGFr) conserved
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
UDP N-acetylglucosamine O-acyltransferase C-terminal
RNA polymerase sigma factor 70 region 4 type 2
Aminoacyl-transfer RNA synthetases class-II family profile
RND efflux pump membrane fusion protein barrel-sandwich
NAD(P) transhydrogenase alpha subunit C-terminal
Interaction with polymerase core subunit RpoC
Phosphorylase b kinase regulatory subunit alpha/beta C-terminal
Membrane fusion protein biotin-lipoyl like
Nitrite/Sulfite reductase ferredoxin-like
1,4-alpha-glucan branching enzyme C-terminal
Glycoside hydrolase family 57 N-terminal
Urease accessory protein UreH-like transmembrane
Cytochrome b/b6 N-terminal region profile
Polypeptide-transport-associated ShlB-type
Molybdopterin cofactor biosynthesis C (MoaC)
Glycogen debranching enzyme bacterial and archaeal type N-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Glycosyl-hydrolase family 116 N-terminal
Glycosyl-hydrolase family 116 catalytic region
Photosystem I reaction center subunit III
TonB-dependent receptor-like beta-barrel
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Glucose-methanol-choline oxidoreductase N-terminal
Polymerase/histidinol phosphatase N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Sodium/calcium exchanger membrane region
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Polysaccharide biosynthesis protein C-terminal
WGxxGxxG-CTERM domain-containing protein
Bacteriophage/plasmid primase P4 C-terminal
Glycosyl transferase family 3 N-terminal
Cation-transporting P-type ATPase N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Prepilin type IV endopeptidase peptidase
Neurotransmitter-gated ion-channel ligand-binding
Neurotransmitter-gated ion-channel transmembrane
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Pseudouridine synthase I TruA alpha/beta
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
SMODS-associated and fused to various effectors
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Heme-copper oxidase subunit III family profile
Bacterial bifunctional deaminase-reductase C-terminal
Bacterial OB-fold domain-containing protein
Ribosomal RNA adenine methylase transferase N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Large ribosomal subunit protein uL15/eL18
Probable endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
Restriction endonuclease type I HsdR N-terminal
NADH-rubredoxin oxidoreductase C-terminal
Type I restriction modification DNA specificity
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Survival protein SurE-like phosphatase/nucleotidase
Alpha-D-phosphohexomutase alpha/beta/alpha
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Penicillin-binding protein transpeptidase
Tetratricopeptide TPR_1 repeat-containing protein
Cell envelope-related transcriptional attenuator
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Important for substrate specificity; cannot use PPi as phosphoryl donor
Solute-binding protein family 3/N-terminal
Cyanobacterial aminoacyl-tRNA synthetase CAAD
May play a role in transmitting local conformational changes
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Cob(I)alamin adenosyltransferase N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
ABC transporter substrate-binding protein PnrA-like
DNA-directed DNA polymerase family A palm
Cytochrome b/b6 C-terminal region profile
Integral membrane protein YccS N-terminal
SUF system FeS cluster assembly SufBD N-terminal
ABC-type uncharacterised transport system
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Phosphatidic acid phosphatase type 2/haloperoxidase
NADH:ubiquinone oxidoreductase 30kDa subunit
Septum formation inhibitor MinC C-terminal
Anaphase-promoting complex subunit 4-like WD40
Translation initiation factor beta propellor-like
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Ferredoxin thioredoxin reductase alpha chain
Alanyl-transfer RNA synthetases family profile
Type IV secretion system coupling protein TraD DNA-binding
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Ribulose bisphosphate carboxylase small subunit
Sugar fermentation stimulation protein C-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
NADH:flavin oxidoreductase/NADH oxidase N-terminal
LPS export ABC transporter periplasmic protein LptC
Could play a key role in the communication between the regulatory and the substrate sites
RNA 2-O ribose methyltransferase substrate binding
Type II secretion system protein GspE N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Photosystem II reaction center protein K
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Arginine decarboxylase C-terminal helical
Anthranilate synthase component I N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Peptidase C-terminal archaeal/bacterial domain-containing protein
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
Light-independent protochlorophyllide reductase subunit B-like C-terminal
Type II restriction endonuclease EcoO109IR
Bacterial Glycosyl hydrolase family 3 C-terminal
ABC-type glycine betaine transport system substrate-binding
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
N6 adenine-specific DNA methyltransferase N-terminal
Inner membrane protein YgaP-like transmembrane
Methionyl-tRNA synthetase anticodon-binding
Lysozyme inhibitor LprI N-terminal domain-containing protein
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Increases the nucleophilicity of the active site Cys
RNA-binding protein Tab2-like N-terminal
RNA-binding protein Tab2/Atab2 C-terminal
Mannose-6-phosphate isomerase type II C-terminal
DNA primase/polymerase bifunctional N-terminal
Lysyl-tRNA synthetase N-terminal transmembrane region
Phosphatidylglycerol lysyltransferase C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Prokaryotic-type class I peptide chain release factors
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Photosystem II cytochrome b559 N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Photosystem II manganese-stabilizing polypeptide
Magnesium chelatase subunit H N-terminal
DNA replication/recombination mediator RecO N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Carbamoyl-phosphate synthase small subunit N-terminal
Type I restriction enzyme R protein N-terminal
Inward rectifier potassium channel C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Glutathionylspermidine synthase pre-ATP-grasp-like
Peptidase M1 membrane alanine aminopeptidase
Type III restriction enzyme C-terminal endonuclease
Cysteine sulfenic acid (-SOH) intermediate
Aconitase A/isopropylmalate dehydratase small subunit swivel
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
CRISPR-associated protein Cas6 C-terminal
Gamma-glutamylcyclotransferase AIG2-like
Haem-binding uptake Tiki superfamily ChaN
Haem-binding uptake Tiki superfamily ChaN domain-containing protein
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Proton acceptor; for glutaminase activity
Plastid lipid-associated protein/fibrillin conserved
Quercetin 2,3-dioxygenase C-terminal cupin
Pyridoxamine 5'-phosphate oxidase Alr4036 family FMN-binding
Pyridoxamine 5'-phosphate oxidase putative
Menaquinone biosynthesis protein MenD middle
Polynucleotide kinase-phosphatase C-terminal
Polynucleotide kinase-phosphatase ligase
Inosine/uridine-preferring nucleoside hydrolase
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Gly-cisPro motif, important for rejection of L-amino acids
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Resolvase/invertase-type recombinase catalytic
Homocysteine biosynthesis enzyme sulfur-incorporation
Glucose-methanol-choline oxidoreductase C-terminal
Peptide methionine sulphoxide reductase MsrA
Small ribosomal subunit protein uS4 N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Ribosome maturation factor RimP N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Heat-inducible transcription repressor HrcA C-terminal
Exonuclease VII large subunit C-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
ATP synthase F1 complex delta/epsilon subunit N-terminal
Sporulation stage II protein D amidase enhancer LytB N-terminal
Cytochrome oxidase subunit II copper A binding
Large ribosomal subunit protein uL2 C-terminal
NIF system FeS cluster assembly NifU C-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Large ribosomal subunit protein uL6 alpha-beta
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
C-type lysozyme inhibitor domain-containing protein
Photosystem II cytochrome b559 alpha subunit lumenal region
CRISPR system ring nuclease SSO1393-like
SGNH hydrolase-type esterase domain-containing protein
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
Na+/H+ antiporter MnhB subunit-related protein
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Schiff-base intermediate with acetaldehyde
6-phosphogluconate dehydrogenase C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Signal transduction histidine kinase dimerisation/phosphoacceptor
Phosphoribosylformylglycinamidine synthase linker
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Reversibly protonated during proton transport
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Magnesium-protoporphyrin IX methyltransferase C-terminal
Type VII secretion system protein EssD-like
NADH:ubiquinone oxidoreductase intermediate-associated protein 30
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Protein O-mannosyl-transferase C-terminal four TM
S-adenosyl-L-homocysteine hydrolase NAD binding
Photosystem I PsaL reaction centre subunit XI
Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal
RNA binding; important for wobble base 34 recognition
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
DNA mismatch repair proteins mutS family
Cytochrome oxidase subunit II transmembrane region profile
Polysaccharide biosynthesis protein CapD-like
Rubisco accumulation factor 1 C-terminal
Rubisco accumulation factor 1 alpha helical
Rubisco accumulation factor 1 helix turn helix
Organic solvent tolerance-like N-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Plays an important role in substrate specificity
Limiting CO2-inducible protein B/C beta carbonyic anhydrase
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal
Coenzyme F420 hydrogenase/dehydrogenase beta subunit N-terminal
Essential for prephenate dehydratase activity
Ribose-phosphate pyrophosphokinase N-terminal