TonB-dependent receptor-like beta-barrel
Lipoprotein SmpA/OmlA domain-containing protein
Major facilitator superfamily (MFS) profile
Cytochrome c-type biogenesis protein CcmE
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
DNA mismatch repair proteins mutS family
Outer membrane protein beta-barrel domain-containing protein
Anthranilate synthase component I N-terminal
Penicillin-binding protein transpeptidase
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Plays an important role in substrate specificity
Ribosomal RNA adenine methylase transferase N-terminal
Alanyl-transfer RNA synthetases family profile
Ribosomal RNA small subunit methyltransferase E methyltransferase
Pyruvate phosphate dikinase AMP/ATP-binding
Could be important to modulate the pK values of the two catalytic cysteine residues
Peptidase S9 prolyl oligopeptidase catalytic
Membrane fusion protein biotin-lipoyl like
RND efflux pump membrane fusion protein barrel-sandwich
Large ribosomal subunit protein uL15/eL18
Type 4 fimbrial biogenesis protein PilX N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Peptide methionine sulphoxide reductase MsrA
Peptide methionine sulfoxide reductase MsrA
RNA 2-O ribose methyltransferase substrate binding
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Aconitase A/isopropylmalate dehydratase small subunit swivel
RNA polymerase sigma factor 70 region 4 type 2
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Tryptophan synthase beta chain-like PALP
PhoD-like phosphatase metallophosphatase
Cation-transporting P-type ATPase N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Solute-binding protein family 3/N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Signal transduction histidine kinase internal region
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Aminoacyl-transfer RNA synthetases class-II family profile
Pili assembly chaperone N-terminal domain-containing protein
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
peptide-methionine (R)-S-oxide reductase
Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Antitoxin Xre/MbcA/ParS-like toxin-binding
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Bacterial type II secretion system protein E
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Amidohydrolase-related domain-containing protein
Electron transfer via tryptophanyl radical
Membrane-bound lytic murein transglycosylase F
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
O-(3'-phospho-DNA)-tyrosine intermediate
ABC-type transport auxiliary lipoprotein component domain-containing protein
Restriction endonuclease AspBHI N-terminal
Spore coat protein U domain-containing protein
Positions MEP for the nucleophilic attack
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Nicotinamide phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Type II secretion system protein GspC N-terminal
Mannose-6-phosphate isomerase type II C-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Chitobiase/beta-hexosaminidases N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Putative regulatory protein FmdB Zinc ribbon
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Polymerase/histidinol phosphatase N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Type II secretion system protein GspI C-terminal
Threonine/serine exporter-like N-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal domain-containing protein
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Cytochrome C biogenesis protein transmembrane
Thiol:disulfide interchange protein DsbD N-terminal
Beta-lactamase hydrolase-like protein phosphatase-like
Plays an important role in discriminating NADH against NADPH
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Translation elongation factor P/YeiP central
Autotransporter domain-containing protein
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
DNA-directed DNA polymerase family A palm
Water stress and hypersensitive response
Sodium symporter small subunit predicted
Phosphatidic acid phosphatase type 2/haloperoxidase
Small ribosomal subunit protein uS4 N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Involved in allosteric activation by GTP
Sodium/calcium exchanger membrane region
Transglycosylase SLT domain-containing protein
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
L,D-transpeptidase catalytic domain-containing protein
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Glycosyl hydrolase-like 10 domain-containing protein
Interaction with polymerase core subunit RpoC
Alpha-D-phosphohexomutase alpha/beta/alpha
Ysc84 actin-binding domain-containing protein
Aminoacyl-tRNA synthetase class I anticodon-binding
Prokaryotic-type class I peptide chain release factors
Glycine zipper 2TM domain-containing protein
Release factor glutamine methyltransferase N-terminal
Nitrite/Sulfite reductase ferredoxin-like
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
HicB-like antitoxin of toxin-antitoxin system
DNA replication/recombination mediator RecO N-terminal
Outer-membrane lipoprotein carrier protein
Carbamoyl-phosphate synthase small subunit N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Right handed beta helix domain-containing protein
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
YbaK/aminoacyl-tRNA synthetase-associated
N-end rule aminoacyl transferase C-terminal
Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
Sugar fermentation stimulation protein C-terminal
Outer membrane protein assembly factor BamE
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Urease accessory protein UreH-like transmembrane
Required for zinc-mediated homotetramerization and catalytic activity
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Important for interaction with partner proteins
Lytic transglycosylase superhelical linker
Adaptive response protein AidB N-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Helix-hairpin-helix DNA-binding motif class 1
Gly-cisPro motif, important for rejection of L-amino acids
Glycine cleavage T-protein C-terminal barrel
Peptidase M1 membrane alanine aminopeptidase domain-containing protein
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
NIF system FeS cluster assembly NifU C-terminal
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Prepilin type IV endopeptidase peptidase
S-adenosylmethionine-dependent methyltransferase
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
NIF system FeS cluster assembly NifU N-terminal
6-phosphogluconate dehydrogenase C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Abnormal spindle-like microcephaly-associated protein ASH
Superoxide dismutase copper/zinc binding
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Biopterin-dependent aromatic amino acid hydroxylase family profile
Isocitrate dehydrogenase kinase/phosphatase (AceK) kinase
Isocitrate dehydrogenase kinase/phosphatase (AceK) regulatory
Heme-copper oxidase subunit III family profile
Proton acceptor; for glutaminase activity
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-104)
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
O-(5'-phospho-DNA)-tyrosine intermediate
Polysaccharide chain length determinant N-terminal
7 transmembrane helices usually fused to an inactive transglutaminase
Inactive transglutaminase fused to 7 transmembrane helices
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal
Coenzyme F420 hydrogenase/dehydrogenase beta subunit N-terminal
Glycosyl transferase family 28 C-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Peptidase MA-like domain-containing protein
Thiamin/hydroxymethyl pyrimidine-binding YkoF putative
Important for substrate binding and specificity
Outer membrane protein assembly factor BamA
Saccharopine dehydrogenase-like C-terminal
Na+/H+ antiporter MnhB subunit-related protein
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Peptidase M10 metallopeptidase domain-containing protein
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Glycosyl transferase family 3 N-terminal
Type II secretion system protein GspG C-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
S-adenosyl-L-homocysteine hydrolase NAD binding
Pyrimidine nucleoside phosphorylase C-terminal
Reversibly protonated during proton transport
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Quercetin 2,3-dioxygenase C-terminal cupin
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Large ribosomal subunit protein uL2 C-terminal
Glycoside-hydrolase family GH114 TIM-barrel
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Arginine decarboxylase C-terminal helical
Gamma-butyrobetaine hydroxylase-like N-terminal
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Exonuclease VII large subunit C-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Cytochrome b561 bacterial/Ni-hydrogenase
Essential for prephenate dehydratase activity
Outer membrane protein assembly factor BamB
Large ribosomal subunit protein uL6 alpha-beta
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Acetyl-CoA hydrolase/transferase C-terminal
Chromosomal replication initiator DnaA C-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Disulphide bond isomerase DsbC/G N-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Sialate O-acetylesterase domain-containing protein
Chromosomal replication initiator protein DnaA
High potential iron-sulfur proteins family profile
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Pseudouridine synthase I TruA alpha/beta
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Resolvase/invertase-type recombinase catalytic
Cytochrome c-type biogenesis protein CcmF C-terminal