Sortilin N-terminal domain-containing protein
Major facilitator superfamily (MFS) profile
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Single-stranded-DNA-specific exonuclease RecJ C-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Interaction with polymerase core subunit RpoC
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Sporulation stage II protein D amidase enhancer LytB N-terminal
Probable transposase IS891/IS1136/IS1341
Bacterial transcription activator effector binding
Cytochrome b/b6 C-terminal region profile
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Septum formation inhibitor MinC C-terminal
Alanyl-transfer RNA synthetases family profile
Flagellar basal body rod protein N-terminal
Transcriptional regulator TetR C-terminal Firmicutes type
RNA 2-O ribose methyltransferase substrate binding
6-phosphogluconate dehydrogenase C-terminal
Glycosyltransferase subfamily 4-like N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Bacterial type II secretion system protein E
Alpha galactosidase C-terminal beta sandwich
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
RNA polymerase sigma factor 70 region 4 type 2
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Copper amine oxidase-like N-terminal domain-containing protein
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Transcription regulator AsnC/Lrp ligand binding
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Peptidase S9 prolyl oligopeptidase catalytic
Flagellar basal-body/hook protein C-terminal
Phage terminase large subunit GpA ATPase
Terminase large subunit GpA endonuclease
Glycosyl hydrolase family 30 beta sandwich
Polysaccharide biosynthesis protein C-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
N6 adenine-specific DNA methyltransferase N-terminal
Polymerase/histidinol phosphatase N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Translation elongation factor P/YeiP central
Ribose-phosphate pyrophosphokinase N-terminal
Schiff-base intermediate with substrate; via pyruvic acid
ABC transporter substrate-binding protein
Pseudouridine synthase I TruA alpha/beta
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
ABC transporter substrate-binding protein PnrA-like
ABC transporter substrate-binding protein PnrA-like domain-containing protein
Exonuclease VII large subunit C-terminal
Cell wall-active antibiotics response LiaF-like C-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Important for beta-aspartyl-AMP intermediate formation
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Phosphatidylglycerol lysyltransferase C-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Schiff-base intermediate with D-ribose 5-phosphate
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Resolvase/invertase-type recombinase catalytic
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Diacylglycerol glucosyltransferase N-terminal
Glycosyl transferase family 28 C-terminal
Cation-transporting P-type ATPase N-terminal
Extracellular endo-alpha-(1->5)-L-arabinanase C-terminal
Schiff-base intermediate with acetaldehyde
Virulence factor membrane-bound polymerase C-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Dipicolinate synthase subunit A N-terminal
Anthranilate synthase component I N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Membrane fusion protein biotin-lipoyl like
ABC-type glycine betaine transport system substrate-binding
Important for interaction with partner proteins
Sporulation stage IV protein A C-terminal
SsuA/THI5-like domain-containing protein
Microcin J25-processing protein McjB C-terminal
Large ribosomal subunit protein bL9 C-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Gly-cisPro motif, important for rejection of L-amino acids
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Penicillin-binding protein transpeptidase
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Plays an important role in substrate specificity
O-(5'-phospho-DNA)-tyrosine intermediate
DNA-directed DNA polymerase family A palm
Tryptophan synthase beta chain-like PALP
UDP N-acetylglucosamine O-acyltransferase C-terminal
Phosphocysteine intermediate; for EIIB activity
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Putative aromatic acid exporter C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
RNA binding; important for wobble base 34 recognition
Glycoside hydrolase GH146 substrate-binding
Could be important to modulate the pK values of the two catalytic cysteine residues
Cytochrome C biogenesis protein transmembrane
Urease accessory protein UreH-like transmembrane
Glyoxalase/fosfomycin resistance/dioxygenase
Glucosamine/galactosamine-6-phosphate isomerase
Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
Transcriptional regulator SgrR N-terminal HTH
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
DNA mismatch repair proteins mutS family
Large ribosomal subunit protein uL15/eL18
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Thiamine pyrophosphate enzyme TPP-binding
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Phage conserved hypothetical protein C-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Polysaccharide chain length determinant N-terminal
Polysaccharide biosynthesis protein CapD-like
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Cell envelope-related transcriptional attenuator
CD-NTase-associated protein 12/Pycsar effector protein TIR
Lysidine-tRNA(Ile) synthetase C-terminal
Phosphotransferase system enzyme I N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Bacterial bifunctional deaminase-reductase C-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Sporulation transcription regulator WhiA N-terminal
Ribonucleotide reductase large subunit C-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Photosynthesis system II assembly factor Ycf48/Hcf136-like domain-containing protein
Ribosomal RNA adenine methylase transferase N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Helix-hairpin-helix DNA-binding motif class 1
Meso-diaminopimelate D-dehydrogenase C-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Bacterial spore germination immunoglobulin-like
Bacterial spore germination immunoglobulin-like domain-containing protein
Solute-binding protein family 5 domain-containing protein
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Flagellar hook-length control protein-like C-terminal
Involved in allosteric activation by GTP
Chromosomal replication initiator DnaA C-terminal
Glycoside hydrolase family 31 N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
RDXXRA motif of the pArg binding pocket involved in allosteric regulation
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Tryptophan RNA-binding attenuator protein
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
D-galactose/methyl-galactoside binding periplasmic protein MglB
Cysteine sulfenic acid (-SOH) intermediate
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Saccharopine dehydrogenase-like C-terminal
Sugar ABC transporter substrate-binding protein
NIF system FeS cluster assembly NifU C-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Magnesium transporter MgtE intracellular domain-containing protein
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Superoxide dismutase copper/zinc binding
Glycoside hydrolase family 42 N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Large ribosomal subunit protein uL6 alpha-beta
Positions MEP for the nucleophilic attack
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Peptide methionine sulphoxide reductase MsrA
Prepilin type IV endopeptidase peptidase
WGxxGxxG-CTERM domain-containing protein
General stress protein FMN-binding split barrel
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
SUF system FeS cluster assembly SufBD N-terminal
Reversibly protonated during proton transport
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Mannose-6-phosphate isomerase type II C-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Influences the redox potential of the prosthetic heme and FAD groups
Involved in heme-bound ligand stabilization and O-O bond activation
Flagellar motor switch protein FliN-like C-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
DNA replication/recombination mediator RecO N-terminal
Glycosyltransferase family 28 N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Shikimate dehydrogenase substrate binding N-terminal
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Endoribonuclease L-PSP/chorismate mutase-like
Elongation factor G-binding protein C-terminal treble-clef zinc-finger
Elongation factor G-binding protein N-terminal
Integron-associated effector binding protein
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Na+/H+ antiporter MnhB subunit-related protein
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Glycerol-3-phosphate dehydrogenase [NAD(P)+]
Cytochrome b/b6 N-terminal region profile
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Beta-lactamase-related domain-containing protein
Type III secretion system flagellar brake protein YcgR PilZN
Flagellar assembly protein FliH/Type III secretion system HrpE
Heme-copper oxidase subunit III family profile
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Type I restriction modification DNA specificity
Phosphoribosylformylglycinamidine synthase linker
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Flagellar Assembly Protein A N-terminal region
Phosphomannose isomerase type I catalytic
Small ribosomal subunit protein uS4 N-terminal
NIF system FeS cluster assembly NifU N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Protein-PII uridylyltransferase N-terminal
Solute-binding protein family 3/N-terminal domain-containing protein
Peptidase M1 membrane alanine aminopeptidase
Could play a key role in the communication between the regulatory and the substrate sites
Thymidylate synthase/dCMP hydroxymethylase
Signal transduction histidine kinase internal region
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
EfeO-type cupredoxin-like domain-containing protein
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Pyrimidine nucleoside phosphorylase C-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
tRNA pseudouridylate synthase B C-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Essential for prephenate dehydratase activity
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Transposase IS116/IS110/IS902 C-terminal
Lysozyme inhibitor LprI N-terminal domain-containing protein
S-adenosylmethionine-dependent methyltransferase
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Large ribosomal subunit protein uL2 C-terminal
Thiamin pyrophosphokinase thiamin-binding
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
ATP synthase F1 complex delta/epsilon subunit N-terminal