Cytochrome b561 bacterial/Ni-hydrogenase
Quercetin 2,3-dioxygenase C-terminal cupin
Aconitase A/isopropylmalate dehydratase small subunit swivel
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
UPF0173 metal-dependent hydrolase A8O14_08990
Pyruvate dehydrogenase E1 component middle
Gamma-glutamylcyclotransferase AIG2-like
Glycosyl transferase family 3 N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Rap1a immunity protein domain-containing protein
Alpha-D-phosphohexomutase alpha/beta/alpha
Type 2A encapsulin shell protein SrpI-like
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Mandelate racemase/muconate lactonizing enzyme C-terminal
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Peptide methionine sulphoxide reductase MsrA
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
NAD(P) transhydrogenase alpha subunit C-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Alanyl-transfer RNA synthetases family profile
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
High potential iron-sulfur proteins family profile
Pyruvate phosphate dikinase AMP/ATP-binding
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
TonB-dependent receptor-like beta-barrel
Pyridine nucleotide-disulphide oxidoreductase dimerisation
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Major facilitator superfamily (MFS) profile
Amidohydrolase 3 domain-containing protein
Important for interaction with partner proteins
Electron transfer via tryptophanyl radical
Pseudouridine synthase I TruA alpha/beta
Outer membrane protein beta-barrel domain-containing protein
Endoribonuclease L-PSP/chorismate mutase-like
O-(3'-phospho-DNA)-tyrosine intermediate
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Release factor glutamine methyltransferase N-terminal
Photosynthetic reaction centre H subunit N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Solute-binding protein family 3/N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
DNA-directed DNA polymerase family A palm
DNA polymerase III subunit delta C-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Plays an important role in substrate specificity
Aminoacyl-transfer RNA synthetases class-II family profile
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Signal recognition particle SRP54 helical bundle
C-type lysozyme inhibitor domain-containing protein
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Anthranilate synthase component I N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
O-(5'-phospho-DNA)-tyrosine intermediate
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Survival protein SurE-like phosphatase/nucleotidase
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Aldehyde oxidase/xanthine dehydrogenase first molybdopterin binding
Aldehyde oxidase/xanthine dehydrogenase second molybdopterin binding
Required for zinc-mediated homotetramerization and catalytic activity
Large ribosomal subunit protein uL15/eL18
Lysidine-tRNA(Ile) synthetase C-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Tetrahydrodipicolinate-N-succinyltransferase chain A
RNA polymerase sigma factor 70 region 4 type 2
Ribose-phosphate pyrophosphokinase N-terminal
Phosphoadenosine phosphosulphate reductase
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Thymidylate synthase/dCMP hydroxymethylase
Ribosomal RNA adenine methylase transferase N-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Disulphide bond isomerase DsbC/G N-terminal
Important for autoinhibition of adenylyltransferase activity
FAD-dependent oxidoreductase 2 FAD binding
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Choloylglycine hydrolase/NAAA C-terminal
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Moybdenum cofactor oxidoreductase dimerisation
Bacterial type II secretion system protein E
CNP1-like uncharacterized domain-containing protein
ABC transporter substrate-binding protein
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
S-adenosyl-L-homocysteine hydrolase NAD binding
AraC-type arabinose-binding/dimerisation domain-containing protein
Polymerase/histidinol phosphatase N-terminal
SsuA/THI5-like domain-containing protein
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
NADH:ubiquinone oxidoreductase 30kDa subunit
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Magnesium-protoporphyrin IX methyltransferase C-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Chalcone isomerase domain-containing protein
Prokaryotic-type class I peptide chain release factors
Poly-beta-hydroxybutyrate polymerase N-terminal
Phosphotransferase system enzyme I N-terminal
RNA 2-O ribose methyltransferase substrate binding
Flavocytochrome c sulphide dehydrogenase flavin-binding
UDP N-acetylglucosamine O-acyltransferase C-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Large ribosomal subunit protein uL2 C-terminal
Proton acceptor; for glutaminase activity
Gamma-butyrobetaine hydroxylase-like N-terminal
Cysteine sulfenic acid (-SOH) intermediate
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Bifunctional metallophosphatase/5'-nucleotidase
Chromosomal replication initiator protein DnaA
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Ysc84 actin-binding domain-containing protein
Nucleophile; cysteine thiosulfonate intermediate
Type I restriction modification DNA specificity
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Beta-lactamase hydrolase-like protein phosphatase-like
Molybdopterin cofactor biosynthesis C (MoaC)
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Lipoprotein SmpA/OmlA domain-containing protein
NADH:ubiquinone oxidoreductase-like 20kDa subunit
DNA replication/recombination mediator RecO N-terminal
Lytic transglycosylase superhelical linker
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Major facilitator superfamily associated
PHA accumulation regulator DNA-binding N-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
RNA binding; important for wobble base 34 recognition
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Sodium/calcium exchanger membrane region
Small ribosomal subunit protein uS4 N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Helix-hairpin-helix DNA-binding motif class 1
Tryptophan synthase beta chain-like PALP
EfeO-type cupredoxin-like domain-containing protein
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Inner membrane protein YgaP-like transmembrane
N-end rule aminoacyl transferase C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Superoxide dismutase copper/zinc binding
Mannose-6-phosphate isomerase type II C-terminal
Interaction with polymerase core subunit RpoC
Metallo-beta-lactamase domain-containing protein
Transposase IS204/IS1001/IS1096/IS1165 DDE
Carbamoyl-phosphate synthase small subunit N-terminal
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Polysaccharide chain length determinant N-terminal
Reversibly protonated during proton transport
Translation elongation factor P/YeiP central
NIF system FeS cluster assembly NifU N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Transglutaminase-like domain-containing protein
Serine aminopeptidase S33 domain-containing protein
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Nitrite/Sulfite reductase ferredoxin-like
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal
Coenzyme F420 hydrogenase/dehydrogenase beta subunit N-terminal
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Prepilin type IV endopeptidase peptidase
Penicillin-binding protein transpeptidase
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Positions MEP for the nucleophilic attack
Type I restriction enzyme R protein N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Light-independent protochlorophyllide reductase subunit B-like C-terminal
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Heme-copper oxidase subunit III family profile
NADH-rubredoxin oxidoreductase C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
3-keto-disaccharide hydrolase domain-containing protein
ABC-type transport auxiliary lipoprotein component
ABC-type transport auxiliary lipoprotein component domain-containing protein
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Exonuclease VII large subunit C-terminal
Photosynthetic reaction center cytochrome c subunit
Essential for prephenate dehydratase activity
NADH:ubiquinone oxidoreductase chain 4 N-terminal
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Pyridoxamine kinase/Phosphomethylpyrimidine kinase