Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Major facilitator superfamily (MFS) profile
FAD-dependent oxidoreductase 2 FAD binding
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Schiff-base intermediate with acetaldehyde
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Cytochrome oxidase subunit II copper A binding
Important for beta-aspartyl-AMP intermediate formation
Phosphatidic acid phosphatase type 2/haloperoxidase
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
RNA polymerase sigma factor 70 region 4 type 2
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Putative cyclic ADP-D-ribose synthase TIR1
Peptidase S9 prolyl oligopeptidase catalytic
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Type VII secretion system protein EssD-like
Type VII secretion system protein EssD-like domain-containing protein
RNA 2-O ribose methyltransferase substrate binding
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
RNA binding; important for wobble base 34 recognition
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
RDXXRA motif of the pArg binding pocket involved in allosteric regulation
Endoribonuclease L-PSP/chorismate mutase-like
O-(5'-phospho-DNA)-tyrosine intermediate
Flagellar basal body rod protein N-terminal
Glycosyltransferase subfamily 4-like N-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Menaquinone biosynthesis protein MenD middle
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Transposase IS116/IS110/IS902 C-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Heat-inducible transcription repressor HrcA C-terminal
Flagellar basal-body/hook protein C-terminal
Bacterial type II secretion system protein E
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Single-stranded-DNA-specific exonuclease RecJ C-terminal
Translation elongation factor P/YeiP central
Flagellar Assembly Protein A N-terminal region
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Cytochrome C biogenesis protein transmembrane
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Homogentisate 1,2-dioxygenase N-terminal
Prepilin type IV endopeptidase peptidase
Inner membrane protein YgaP-like transmembrane
Polymerase/histidinol phosphatase N-terminal
Polysaccharide biosynthesis protein CapD-like
Tryptophan synthase beta chain-like PALP
Polysaccharide biosynthesis protein C-terminal
SbsC C-terminal domain-containing protein
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Heme-copper oxidase subunit III family profile
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
HTH-type transcriptional regulator MT1864/Rv1816-like C-terminal
Solute-binding protein family 3/N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Sporulation initiation phosphotransferase B C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Bacterial transcription activator effector binding
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Type I restriction modification DNA specificity
Phosphoribosylformylglycinamidine synthase linker
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Cytochrome oxidase subunit II transmembrane region profile
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Aconitase A/isopropylmalate dehydratase small subunit swivel
Activator of Hsp90 ATPase homologue 1-like C-terminal
Essential for prephenate dehydratase activity
NIF system FeS cluster assembly NifU N-terminal
Penicillin-binding protein transpeptidase
DNA mismatch repair proteins mutS family
Involved in allosteric activation by GTP
S-adenosylmethionine-dependent methyltransferase
Sporulation stage II protein D amidase enhancer LytB N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Glycosyl transferase family 3 N-terminal
Urease accessory protein UreH-like transmembrane
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Ferrous iron transport protein B C-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
O-(3'-phospho-DNA)-tyrosine intermediate
Thiamin pyrophosphokinase thiamin-binding
DNA polymerase III delta subunit C-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
tRNA pseudouridylate synthase B C-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
Schiff-base intermediate with D-ribose 5-phosphate
Anthranilate synthase component I N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Pyrimidine nucleoside phosphorylase C-terminal
Cytochrome b/b6 N-terminal region profile
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Cell envelope-related transcriptional attenuator
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Cell wall-active antibiotics response LiaF-like C-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Diacylglycerol glucosyltransferase N-terminal
Sporulation stage IV protein A C-terminal
Copper amine oxidase-like N-terminal domain-containing protein
Helix-turn-helix conjugative transposon-like
Pseudouridine synthase I TruA alpha/beta
Pyridoxamine 5'-phosphate oxidase putative
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Could be important to modulate the pK values of the two catalytic cysteine residues
Phosphocysteine intermediate; for EIIB activity
Carbamoyl-phosphate synthase small subunit N-terminal
Exonuclease VII large subunit C-terminal
Resolvase/invertase-type recombinase catalytic
Shikimate dehydrogenase substrate binding N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Tryptophan RNA-binding attenuator protein
Cytochrome b561 bacterial/Ni-hydrogenase
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
DNA-directed DNA polymerase family A palm
Alanyl-transfer RNA synthetases family profile
Putative cyclic ADP-D-ribose synthase TIR2
NADH:ubiquinone oxidoreductase-like 20kDa subunit
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
SUF system FeS cluster assembly SufBD N-terminal
DnaJ homologue subfamily C member 28 conserved
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Molybdopterin cofactor biosynthesis C (MoaC)
Phosphotransferase system enzyme I N-terminal
Cation-transporting P-type ATPase N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
nitrite reductase (cytochrome; ammonia-forming)
Cytochrome b/b6 C-terminal region profile
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Membrane insertase YidC/Oxa/ALB C-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Dipicolinate synthase subunit A N-terminal
Large ribosomal subunit protein uL15/eL18
Aspartate/homoserine dehydrogenase NAD-binding
ABC transporter substrate-binding protein PnrA-like
Flagellar motor switch protein FliN-like C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Na+-translocating membrane potential-generating system MpsC
N6 adenine-specific DNA methyltransferase N-terminal
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Threonine/serine exporter-like N-terminal
Quinolinate phosphoribosyl transferase N-terminal
Flagellar hook-length control protein-like C-terminal
General stress protein FMN-binding split barrel
Major facilitator superfamily associated
Chromosomal replication initiator DnaA C-terminal
Small ribosomal subunit protein uS4 N-terminal
DNA replication/recombination mediator RecO N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Putative component of 'biosynthetic module'
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Superoxide dismutase copper/zinc binding
Influences the redox potential of the prosthetic heme and FAD groups
Involved in heme-bound ligand stabilization and O-O bond activation
Alpha-glycerophosphate oxidase C-terminal
Na+/H+ antiporter MnhB subunit-related protein
Prokaryotic-type class I peptide chain release factors
D-galactarate/Altronate dehydratase C-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
6-phosphogluconate dehydrogenase C-terminal
Polysaccharide chain length determinant N-terminal
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 5 domain-containing protein
Elongation factor G-binding protein C-terminal treble-clef zinc-finger
Elongation factor G-binding protein N-terminal
Positions MEP for the nucleophilic attack
Methylguanine DNA methyltransferase ribonuclease-like
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Large ribosomal subunit protein uL2 C-terminal
Important for interaction with partner proteins
Alpha-D-phosphohexomutase alpha/beta/alpha
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
Putative aromatic acid exporter C-terminal
Large ribosomal subunit protein uL6 alpha-beta
Outer membrane lipoprotein carrier protein LolA
DNA-directed RNA polymerase RpoA/D/Rpb3-type
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Type III secretion system flagellar brake protein YcgR PilZN
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Phosphodiester glycosidase domain-containing protein
Sporulation transcription regulator WhiA N-terminal
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Release factor glutamine methyltransferase N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Cysteine sulfenic acid (-SOH) intermediate
Integron-associated effector binding protein
ABC-type glycine betaine transport system substrate-binding
ATP synthase F1 complex delta/epsilon subunit N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Glycine cleavage T-protein C-terminal barrel
Plays an important role in substrate specificity
Meso-diaminopimelate D-dehydrogenase C-terminal
2,4-diaminopentanoate dehydrogenase C-terminal
Anti-bacteriophage protein A/HamA C-terminal
Tellurite resistance methyltransferase TehB-like
Glucosamine/galactosamine-6-phosphate isomerase
Non-canonical purine NTP phosphatase/PRRC1
Ribose-phosphate pyrophosphokinase N-terminal
Lactate utilization protein B C-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Sodium/calcium exchanger membrane region
Interaction with polymerase core subunit RpoC
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Gram-positive cocci surface proteins LPxTG
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Biopterin-dependent aromatic amino acid hydroxylase family profile
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding