Important for interaction with partner proteins
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Flagellar basal-body/hook protein C-terminal
Cytochrome b/b6 N-terminal region profile
Flagellar hook-associated protein 2 N-terminal
Outer membrane lipoprotein BamD-like domain-containing protein
F420-non-reducing hydrogenase iron-sulfur subunit D
CobB/CobQ-like glutamine amidotransferase
Electron transfer flavoprotein alpha/beta-subunit N-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Release factor glutamine methyltransferase N-terminal
Bacterial type II secretion system protein E
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Type II secretion system protein GspE N-terminal
Moybdenum cofactor oxidoreductase dimerisation
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
RND efflux pump membrane fusion protein barrel-sandwich
NIF system FeS cluster assembly NifU N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Homocysteine biosynthesis enzyme sulfur-incorporation
ATP synthase F1 complex delta/epsilon subunit N-terminal
Siroheme decarboxylase AsnC-like ligand binding
RNA 2-O ribose methyltransferase substrate binding
Major facilitator superfamily (MFS) profile
Reversibly protonated during proton transport
TRASH transcription regulator C-terminal archaeal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Cation-transporting P-type ATPase N-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Tryptophan synthase beta chain-like PALP
Glycosyltransferase subfamily 4-like N-terminal
Sodium/calcium exchanger membrane region
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
N(4)-bis(aminopropyl)spermidine synthase C-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Flagellar basal body rod protein N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
tRNA pseudouridylate synthase B C-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Pyruvate/ketoisovalerate oxidoreductase catalytic
Pyruvate phosphate dikinase AMP/ATP-binding
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Lipoprotein SmpA/OmlA domain-containing protein
Transcription regulator AsnC/Lrp ligand binding
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Prepilin type IV endopeptidase peptidase
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Flagellar motor switch protein FliN-like C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Helix-hairpin-helix DNA-binding motif class 1
Polymerase/histidinol phosphatase N-terminal
tRNA (guanine-N(1)-)-methyltransferase C-terminal
Penicillin-binding protein transpeptidase
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Thiamine pyrophosphate enzyme TPP-binding
Methylene-tetrahydrofolate reductase C-terminal
RNA binding; important for wobble base 34 recognition
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Large ribosomal subunit protein uL6 alpha-beta
TonB-dependent receptor-like beta-barrel
S-adenosyl-L-homocysteine hydrolase NAD binding
Putative regulatory protein FmdB Zinc ribbon
DnaJ homologue subfamily C member 28 conserved
Gfo/Idh/MocA-like oxidoreductase N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Solute-binding protein family 3/N-terminal
Alanyl-transfer RNA synthetases family profile
Transcription factor NikR nickel binding C-terminal
Glycogen debranching enzyme bacterial and archaeal type N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Increases nucleophilicity of active site Cys
Proton acceptor; for FBP phosphatase activity
Proton donor/acceptor; for FBP aldolase activity
Schiff-base intermediate with DHAP; for FBP aldolase activity
Alginate export domain-containing protein
Important for substrate specificity; cannot use PPi as phosphoryl donor
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Transposase IS116/IS110/IS902 C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Proton acceptor; for glutaminase activity
Cytochrome b561 bacterial/Ni-hydrogenase
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Could be important to modulate the pK values of the two catalytic cysteine residues
Cysteine sulfenic acid (-SOH) intermediate
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Glycoside hydrolase family 57 N-terminal
Large ribosomal subunit protein uL2 C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
S-adenosylmethionine-dependent methyltransferase
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Disulphide bond isomerase DsbC/G N-terminal
Chromosomal replication initiator DnaA C-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Signal transduction histidine kinase internal region
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Bacterial bifunctional deaminase-reductase C-terminal
Glutamate synthase alpha subunit C-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Schiff-base intermediate with substrate; via pyruvic acid
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Survival protein SurE-like phosphatase/nucleotidase
DNA mismatch repair proteins mutS family
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Formylmethanofuran dehydrogenase subunit E
CO dehydrogenase/acetyl-CoA synthase complex beta subunit C-terminal
Carbon monoxide dehydrogenase subunit alpha ,N-terminal
Phosphoribosylformylglycinamidine synthase linker
Lysidine-tRNA(Ile) synthetase C-terminal
Myo-inositol-1-phosphate synthase GAPDH-like
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Phosphatidic acid phosphatase type 2/haloperoxidase
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Glycosyl transferase family 3 N-terminal
Essential for prephenate dehydratase activity
Prokaryotic-type class I peptide chain release factors
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Trigger factor ribosome-binding bacterial
Plays an important role in substrate specificity
Important for beta-aspartyl-AMP intermediate formation
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal domain-containing protein
Positions MEP for the nucleophilic attack
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Probable endolytic peptidoglycan transglycosylase RlpA
Small ribosomal subunit protein uS4 N-terminal
Type III restriction enzyme C-terminal endonuclease
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Translation elongation factor P/YeiP central
Pseudouridine synthase I TruA alpha/beta
Flagellar hook-length control protein-like C-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Flagellar Assembly Protein A N-terminal region
DNA replication/recombination mediator RecO N-terminal
RNA 3'-terminal phosphate cyclase insert
Flagellar assembly protein FliH/Type III secretion system HrpE
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Magnesium transporter MgtE intracellular
NIF system FeS cluster assembly NifU C-terminal