Sporulation transcription regulator WhiA N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Glycosyltransferase subfamily 4-like N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Threonine/serine exporter-like N-terminal
Solute-binding protein family 3/N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Cell wall-active antibiotics response LiaF-like C-terminal
FAD-dependent oxidoreductase 2 FAD binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Inosine/uridine-preferring nucleoside hydrolase
Aminoacyl-transfer RNA synthetases class-II family profile
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Carbamoyl-phosphate synthase small subunit N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Polysaccharide chain length determinant N-terminal
Major facilitator superfamily (MFS) profile
RNA 2-O ribose methyltransferase substrate binding
Sodium/calcium exchanger membrane region
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Peptidoglycan recognition protein family
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Phosphatidate phosphatase APP1 catalytic
UDP-glucose/GDP-mannose dehydrogenase C-terminal
6-phosphogluconate dehydrogenase NADP-binding
Protocatechuate 3,4-dioxygenase beta subunit N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Reversibly protonated during proton transport
Prokaryotic-type class I peptide chain release factors
Pyruvate dehydrogenase E1 component middle
O-(5'-phospho-DNA)-tyrosine intermediate
SUF system FeS cluster assembly SufBD N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Gram-positive cocci surface proteins LPxTG domain-containing protein
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
RNA polymerase sigma factor 70 region 4 type 2
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Pyruvate phosphate dikinase AMP/ATP-binding
4'-phosphopantetheinyl transferase N-terminal
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
Tryptophan synthase beta chain-like PALP
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
Arabinofuranosyltransferase AftA C-terminal
Arabinofuranosyltransferase AftA N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
C4-dicarboxylate ABC transporter substrate-binding protein
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Solute-binding protein family 5 domain-containing protein
Phosphocysteine intermediate; for EIIB activity
N6 adenine-specific DNA methyltransferase N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Large ribosomal subunit protein uL15/eL18
Meso-diaminopimelate D-dehydrogenase C-terminal
ABC transporter substrate-binding protein
Cytochrome b561 bacterial/Ni-hydrogenase
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Endoribonuclease L-PSP/chorismate mutase-like
Peptidase S9 prolyl oligopeptidase catalytic
SMP-30/Gluconolactonase/LRE-like region domain-containing protein
Penicillin-binding protein transpeptidase
Membrane insertase YidC/Oxa/ALB C-terminal
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Schiff-base intermediate with substrate; via pyruvic acid
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Could play a key role in the communication between the regulatory and the substrate sites
Peptidase M1 membrane alanine aminopeptidase
Type I restriction modification DNA specificity
RNA binding; important for wobble base 34 recognition
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
NIF system FeS cluster assembly NifU N-terminal
Bacterial type II secretion system protein E
Phosphatidic acid phosphatase type 2/haloperoxidase
Essential for prephenate dehydratase activity
Methionyl-tRNA synthetase anticodon-binding
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Cytochrome b/b6 N-terminal region profile
Large ribosomal subunit protein bL12 C-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Chromosomal replication initiator DnaA C-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
CobB/CobQ-like glutamine amidotransferase
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
DNA-directed DNA polymerase family A palm
Electron transfer via tryptophanyl radical
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Alpha-D-phosphohexomutase alpha/beta/alpha
Glycosyl transferase family 3 N-terminal
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Type IV secretion system coupling protein TraD DNA-binding
Large ribosomal subunit protein bL12 oligomerization
Release factor glutamine methyltransferase N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
DNA primase/polymerase bifunctional N-terminal
Positions MEP for the nucleophilic attack
Important for beta-aspartyl-AMP intermediate formation
Phosphomannose isomerase type I catalytic
Phosphomannose isomerase type I helical insertion
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Na+/H+ antiporter MnhB subunit-related protein
Molybdopterin cofactor biosynthesis C (MoaC)
Mandelate racemase/muconate lactonizing enzyme C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Phosphoadenosine phosphosulphate reductase
Protein O-mannosyl-transferase C-terminal four TM
Alanyl-transfer RNA synthetases family profile
Schiff-base intermediate with D-ribose 5-phosphate
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal
Coenzyme F420 hydrogenase/dehydrogenase beta subunit N-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Resolvase/invertase-type recombinase catalytic
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Alpha-glycerophosphate oxidase C-terminal
Cobalamin-independent methionine synthase MetE N-terminal
Pseudouridine synthase I TruA alpha/beta
Formamidopyrimidine-DNA glycosylase catalytic
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Phosphotransferase system enzyme I N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Isoglutamyl lysine isopeptide (Glu-Lys) (interchain with K-? in acceptor proteins)
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Schiff-base intermediate with acetaldehyde
Cytochrome C biogenesis protein transmembrane
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Cell wall-binding repeat 2 family protein
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
DNA replication/recombination mediator RecO N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Sugar ABC transporter substrate-binding protein
Small ribosomal subunit protein uS4 N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
tRNA(Ile)-lysidine synthase substrate-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Anthranilate synthase component I N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Large ribosomal subunit protein uL2 C-terminal
Cell envelope-related transcriptional attenuator
Methylguanine DNA methyltransferase ribonuclease-like
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
L,D-transpeptidase catalytic domain-containing protein
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Peptide methionine sulphoxide reductase MsrA
Glucosamine/galactosamine-6-phosphate isomerase
Phosphoribosylformylglycinamidine synthase linker
Gram-positive cocci surface proteins LPxTG
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Exonuclease VII large subunit C-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Nitrite/Sulfite reductase ferredoxin-like
Activator of Hsp90 ATPase homologue 1-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
PhoD-like phosphatase metallophosphatase
Excalibur calcium-binding domain-containing protein
Phenol hydroxylase C-terminal dimerisation
Myo-inositol-1-phosphate synthase GAPDH-like
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Right handed beta helix domain-containing protein
Bacterial transcription activator effector binding
6-phosphogluconate dehydrogenase C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Involved in ionization of N3 of dUMP, leading to its activation
Helix-hairpin-helix DNA-binding motif class 1
Translation elongation factor P/YeiP central
Resuscitation-promoting factor Rpf1 C-terminal
Resuscitation-promoting factor core lysozyme-like
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation