Polymerase/histidinol phosphatase N-terminal
Arginine decarboxylase C-terminal helical
Dinitrogenase iron-molybdenum cofactor biosynthesis
RagB/SusD family nutrient uptake outer membrane protein
Polysaccharide chain length determinant N-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Aminoacyl-transfer RNA synthetases class-II family profile
RNA polymerase sigma factor 70 region 4 type 2
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
RNA 2-O ribose methyltransferase substrate binding
Glycosyltransferase subfamily 4-like N-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Metallo-beta-lactamase domain-containing protein
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Peptidase S9 prolyl oligopeptidase catalytic
Putative auto-transporter adhesin head GIN
Membrane fusion protein biotin-lipoyl like
Transposase IS116/IS110/IS902 C-terminal
Trigger factor ribosome-binding bacterial
Gfo/Idh/MocA-like oxidoreductase C-terminal
Transposase IS204/IS1001/IS1096/IS1165 DDE
Transposase IS204/IS1001/IS1096/IS1165 helix-turn-helix
Pseudouridine synthase I TruA alpha/beta
Glucosamine/galactosamine-6-phosphate isomerase
3-keto-disaccharide hydrolase domain-containing protein
Tryptophan synthase beta chain-like PALP
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Large ribosomal subunit protein bL9 C-terminal
tRNA pseudouridylate synthase B C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Alpha-L-rhamnosidase six-hairpin glycosidase
Bacterial alpha-L-rhamnosidase N-terminal
Helix-hairpin-helix DNA-binding motif class 1
O-(5'-phospho-DNA)-tyrosine intermediate
TonB-dependent receptor-like beta-barrel
Glycosyl-hydrolase 97 C-terminal oligomerisation
Cytochrome C biogenesis protein transmembrane
Thiol:disulfide interchange protein DsbD N-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Beta-hexosaminidase bacterial type N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Anthranilate synthase component I N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Outer membrane protein beta-barrel domain-containing protein
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Thiamine pyrophosphate enzyme TPP-binding
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Outer membrane lipoprotein carrier protein LolA
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Helix-hairpin-helix domain-containing protein
Unsaturated rhamnogalacturonyl hydrolase
Alanyl-transfer RNA synthetases family profile
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Major facilitator superfamily (MFS) profile
Lysidine-tRNA(Ile) synthetase C-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Release factor glutamine methyltransferase N-terminal
Glycosyl transferase family 3 N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Fibronectin type-III domain-containing protein
N6 adenine-specific DNA methyltransferase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Glycoside hydrolase family 38 N-terminal
RNA binding; important for wobble base 34 recognition
Type ISP restriction-modification enzyme LLaBIII C-terminal specificity
Prokaryotic-type class I peptide chain release factors
Alpha-L-glutamate ligase-related protein ATP-grasp
Quercetin 2,3-dioxygenase C-terminal cupin
Proton acceptor; for glutaminase activity
Gliding motility-associated protein GldM C-terminal
Gliding motility-associated protein GldM N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
ATPsynthase alpha/beta subunit N-terminal extension
Gfo/Idh/MocA-like oxidoreductase bacterial type C-terminal
Menaquinone biosynthesis protein MenD middle
Thiamine pyrophosphate enzyme N-terminal TPP-binding
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Putative oxidoreductase/dehydrogenase Rossmann-like
Late embryogenesis abundant protein LEA-2 subgroup
RND efflux pump membrane fusion protein barrel-sandwich
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Beta-galactosidase trimerisation domain-containing protein
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Glycoside hydrolase family 42 N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Could be important to modulate the pK values of the two catalytic cysteine residues
Shikimate dehydrogenase substrate binding N-terminal
Positions MEP for the nucleophilic attack
Signal transduction histidine kinase internal region
Plays an important role in substrate specificity
Sporulation stage II protein D amidase enhancer LytB N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Phosphatidylglycerol lysyltransferase C-terminal
Type IX secretion system protein PorV domain-containing protein
Large ribosomal subunit protein uL6 alpha-beta
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Large ribosomal subunit protein uL2 C-terminal
SUF system FeS cluster assembly SufBD N-terminal
DNA replication/recombination mediator RecO N-terminal
Endonuclease/exonuclease/phosphatase domain-containing protein
Phosphatidic acid phosphatase type 2/haloperoxidase
Erythronate-4-phosphate dehydrogenase dimerisation
Outer membrane lipoprotein-sorting protein
SusD/RagB family nutrient-binding outer membrane lipoprotein
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Xylose isomerase-like TIM barrel domain-containing protein
Exonuclease VII large subunit C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
NAD(P) transhydrogenase alpha subunit C-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
ADP-ribosylglycohydrolase family protein
Large ribosomal subunit protein uL15/eL18
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Restriction system protein Mrr-like N-terminal
Glycosyl hydrolases family 2 sugar binding
Pyruvate phosphate dikinase AMP/ATP-binding
Aspartate/homoserine dehydrogenase NAD-binding
Penicillin-binding protein transpeptidase
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Glycogen debranching enzyme bacterial and archaeal type N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Thymidylate synthase/dCMP hydroxymethylase
Small ribosomal subunit protein uS4 N-terminal
Outer membrane lipoprotein BamD-like domain-containing protein
Cysteine sulfenic acid (-SOH) intermediate
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Polysaccharide biosynthesis protein C-terminal
Translation elongation factor P/YeiP central
Cell wall-active antibiotics response LiaF-like C-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Inosine/uridine-preferring nucleoside hydrolase
Right handed beta helix domain-containing protein
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
S-adenosyl-L-homocysteine hydrolase NAD binding
Type III restriction enzyme C-terminal endonuclease
Saccharopine dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
DNA mismatch repair proteins mutS family
Organic solvent tolerance-like N-terminal
6-phosphogluconate dehydrogenase C-terminal
Ribonucleotide reductase large subunit C-terminal
ssDNA thymidine ADP-ribosyltransferase DarT
Important for substrate specificity; cannot use PPi as phosphoryl donor
Ribosomal RNA adenine methylase transferase N-terminal
Glycoside hydrolase family 5 domain-containing protein
Important for beta-aspartyl-AMP intermediate formation
Sodium/calcium exchanger membrane region
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Peptide-N-glycosidase F N-terminal domain-containing protein
Probable endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
UDP N-acetylglucosamine O-acyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Sulfatase-modifying factor enzyme domain-containing protein
Glycine cleavage T-protein C-terminal barrel
Non-reducing end beta-L-arabinofuranosidase
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Glycoside hydrolase family 57 N-terminal
Microcystin LR degradation protein MlrC C-terminal
Microcystin LR degradation protein MlrC N-terminal
DNA-directed DNA polymerase family A palm
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Glycoside hydrolase family 20 catalytic domain-containing protein
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Carboxypeptidase-like regulatory domain-containing protein
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Ribose-phosphate pyrophosphokinase N-terminal
Type I restriction enzyme R protein N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Essential for prephenate dehydratase activity
Urease accessory protein UreH-like transmembrane
Meso-diaminopimelate D-dehydrogenase C-terminal
HPr(Ser) kinase/phosphorylase N-terminal