Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Large ribosomal subunit protein uL30-like ferredoxin-like fold
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Phosphomannose isomerase type I catalytic
Phosphomannose isomerase type I helical insertion
Acyl-CoA dehydrogenase/oxidase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Restriction system protein Mrr-like N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Helix-hairpin-helix DNA-binding motif class 1
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Major facilitator superfamily (MFS) profile
DNA replication/recombination mediator RecO N-terminal
Phosphocysteine intermediate; for EIIB activity
O-(3'-phospho-DNA)-tyrosine intermediate
RNA polymerase sigma factor 70 region 4 type 2
Actinobacterial surface-anchored protein domain
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Resolvase/invertase-type recombinase catalytic
Thymidylate synthase/dCMP hydroxymethylase
PhoD-like phosphatase metallophosphatase
Tryptophan synthase beta chain-like PALP
Large ribosomal subunit protein uL6 alpha-beta
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Penicillin-binding protein transpeptidase
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Ribosomal RNA adenine methylase transferase N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Cytochrome b/b6 N-terminal region profile
Phosphoribosylformylglycinamidine synthase linker
Glycosyl transferase family 3 N-terminal
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Arabinofuranosyltransferase AftA C-terminal
Arabinofuranosyltransferase AftA N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Threonine/serine exporter-like N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Peptidase S9 prolyl oligopeptidase catalytic
Solute-binding protein family 3/N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Aminoacyl-transfer RNA synthetases class-II family profile
Exonuclease VII large subunit C-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Large ribosomal subunit protein uL15/eL18
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Prokaryotic-type class I peptide chain release factors
Important for substrate specificity; cannot use PPi as phosphoryl donor
Pyridine nucleotide-disulphide oxidoreductase dimerisation
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Na+/H+ antiporter MnhB subunit-related protein
Peptidoglycan recognition protein family
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Isoglutamyl lysine isopeptide (Glu-Lys) (interchain with K-? in acceptor proteins)
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Sporulation transcription regulator WhiA N-terminal
RNA binding; important for wobble base 34 recognition
4'-phosphopantetheinyl transferase N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Cysteine sulfenic acid (-SOH) intermediate
Glycosyltransferase subfamily 4-like N-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Cobalamin-independent methionine synthase MetE N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
YbaK/aminoacyl-tRNA synthetase-associated
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Formamidopyrimidine-DNA glycosylase catalytic
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Resuscitation-promoting factor Rpf1 C-terminal
Resuscitation-promoting factor core lysozyme-like
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Glycine cleavage T-protein C-terminal barrel
ABC-type transport system involved in multi-copper enzyme maturation, permease component
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Release factor glutamine methyltransferase N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Rv2525c-like glycoside hydrolase-like domain-containing protein
TetR transcriptional regulator CgmR-like C-terminal
Interaction with polymerase core subunit RpoC
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
L-seryl-tRNA selenium transferase N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
RNA 2-O ribose methyltransferase substrate binding
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
HTH-type transcriptional regulator MT1864/Rv1816-like C-terminal
Phosphatidate phosphatase APP1 catalytic
ATP synthase F1 complex delta/epsilon subunit N-terminal
Calcineurin-like phosphoesterase domain-containing protein
Aconitase A/isopropylmalate dehydratase small subunit swivel
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Inosine/uridine-preferring nucleoside hydrolase
Ribosome maturation factor RimP N-terminal
Peptidase M1 membrane alanine aminopeptidase
Endoribonuclease L-PSP/chorismate mutase-like
Cell envelope-related transcriptional attenuator
Acyl-CoA dehydrogenase/oxidase N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Reversibly protonated during proton transport
Anthranilate synthase component I N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
ATP-dependent DNA helicase RecG C-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Large ribosomal subunit protein uL2 C-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
Gram-positive cocci surface proteins LPxTG
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Cytochrome C biogenesis protein transmembrane
Important for beta-aspartyl-AMP intermediate formation
Alanyl-transfer RNA synthetases family profile
Nitrite/Sulfite reductase ferredoxin-like
Schiff-base intermediate with D-ribose 5-phosphate
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Peptide methionine sulphoxide reductase MsrA
6-phosphogluconate dehydrogenase C-terminal
Small ribosomal subunit protein uS4 N-terminal
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Phosphotransferase system enzyme I N-terminal
Essential for prephenate dehydratase activity
Polymerase/histidinol phosphatase N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
CobB/CobQ-like glutamine amidotransferase
Molybdopterin cofactor biosynthesis C (MoaC)
Positions MEP for the nucleophilic attack
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Alpha-glycerophosphate oxidase C-terminal
Involved in ionization of N3 of dUMP, leading to its activation
Cell wall-active antibiotics response LiaF-like C-terminal
Type I restriction modification DNA specificity
Plays an important role in substrate specificity
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
NIF system FeS cluster assembly NifU N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Translation elongation factor P/YeiP central