Pyridine nucleotide-disulphide oxidoreductase dimerisation
4'-phosphopantetheinyl transferase N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Arabinofuranosyltransferase AftA C-terminal
Arabinofuranosyltransferase AftA N-terminal
Positions MEP for the nucleophilic attack
Membrane insertase YidC/Oxa/ALB C-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Cytochrome C biogenesis protein transmembrane
Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-? in acceptor proteins)
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
ABC-type glycine betaine transport system substrate-binding
Could play a key role in the communication between the regulatory and the substrate sites
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Pyruvate dehydrogenase E1 component middle
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Phosphotransferase system enzyme I N-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Major facilitator superfamily (MFS) profile
Ribosomal RNA adenine methylase transferase N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Penicillin-binding protein transpeptidase
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Sporulation transcription regulator WhiA N-terminal
Essential for prephenate dehydratase activity
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Schiff-base intermediate with D-ribose 5-phosphate
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
DNA replication/recombination mediator RecO N-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Glycosyl transferase family 3 N-terminal
RNA binding; important for wobble base 34 recognition
Bacterial type II secretion system protein E
Anthranilate synthase component I N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Glucosamine/galactosamine-6-phosphate isomerase
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Tryptophan synthase beta chain-like PALP
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Phosphoadenosine phosphosulphate reductase
Peptidase M1 membrane alanine aminopeptidase
YbaK/aminoacyl-tRNA synthetase-associated
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Na+/H+ antiporter MnhB subunit-related protein
Inosine/uridine-preferring nucleoside hydrolase
Schiff-base intermediate with acetaldehyde
O-(3'-phospho-DNA)-tyrosine intermediate
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Threonine/serine exporter-like N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Cell envelope-related transcriptional attenuator
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Phosphatidic acid phosphatase type 2/haloperoxidase
Important for beta-aspartyl-AMP intermediate formation
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Solute-binding protein family 3/N-terminal
Glycine cleavage T-protein C-terminal barrel
Phosphoribosylformylglycinamidine synthase linker
ATP synthase F1 complex delta/epsilon subunit N-terminal
Prokaryotic-type class I peptide chain release factors
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Alanyl-transfer RNA synthetases family profile
Interaction with polymerase core subunit RpoC
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Important for substrate specificity; cannot use PPi as phosphoryl donor
Galactofuranosyltransferase GlfT2 N-terminal
Galactofuranosyltransferase-2 C-terminal
Translation elongation factor P/YeiP central
Pseudouridine synthase I TruA alpha/beta
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Restriction system protein Mrr-like N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Phosphocysteine intermediate; for EIIB activity
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Ribose-phosphate pyrophosphokinase N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
tRNA(Ile)-lysidine synthase substrate-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Rv2525c-like glycoside hydrolase-like domain-containing protein
Peptidase S9 prolyl oligopeptidase catalytic
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Large ribosomal subunit protein uL2 C-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Cell wall-active antibiotics response LiaF-like C-terminal
Large ribosomal subunit protein uL15/eL18
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
NIF system FeS cluster assembly NifU N-terminal
Phosphatidate phosphatase APP1 catalytic
Gly-cisPro motif, important for rejection of L-amino acids
Alpha-D-phosphohexomutase alpha/beta/alpha
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
RNA 2-O ribose methyltransferase substrate binding
Resuscitation-promoting factor Rpf1 C-terminal
Resuscitation-promoting factor core lysozyme-like
Phosphomannose isomerase type I catalytic
Phosphomannose isomerase type I helical insertion
Endoribonuclease L-PSP/chorismate mutase-like
Chemotaxis methyl-accepting receptor HlyB-like 4HB MCP
Polymerase/histidinol phosphatase N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Chromosomal replication initiator DnaA C-terminal
Ionotropic glutamate receptor C-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Alpha-glycerophosphate oxidase C-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Large ribosomal subunit protein uL6 alpha-beta
Could be important to modulate the pK values of the two catalytic cysteine residues
Cell wall-binding repeat 2 family protein
Cytochrome b/b6 N-terminal region profile
Nucleophile; cysteine thiosulfonate intermediate
Involved in ionization of N3 of dUMP, leading to its activation
Release factor glutamine methyltransferase N-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Peptide methionine sulphoxide reductase MsrA
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
Gram-positive cocci surface proteins LPxTG
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Putative host cell surface-exposed lipoprotein Ltp-like HTH region
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Helix-hairpin-helix DNA-binding motif class 1
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Nitrite/Sulfite reductase ferredoxin-like
CobB/CobQ-like glutamine amidotransferase
Heat-inducible transcription repressor HrcA C-terminal
Small ribosomal subunit protein uS4 N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Exonuclease VII large subunit C-terminal
ATP-dependent DNA helicase RecG C-terminal
Plays an important role in substrate specificity
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Reversibly protonated during proton transport
TetR transcriptional regulator CgmR-like C-terminal
Acyltransferase MbtK/IucB-like conserved
Thymidylate synthase/dCMP hydroxymethylase
Myo-inositol-1-phosphate synthase GAPDH-like
Mandelate racemase/muconate lactonizing enzyme C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal