Phosphoribosylformylglycinamidine synthase linker
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Cell envelope-related transcriptional attenuator
Phosphomannose isomerase type I catalytic
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Translation elongation factor P/YeiP central
Glucosamine/galactosamine-6-phosphate isomerase
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
ATP-dependent DNA helicase RecG C-terminal
DNA replication/recombination mediator RecO N-terminal
Major facilitator superfamily (MFS) profile
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
YbaK/aminoacyl-tRNA synthetase-associated
Phosphatidic acid phosphatase type 2/haloperoxidase
Solute-binding protein family 3/N-terminal
Cytochrome b/b6 N-terminal region profile
Aminoacyl-transfer RNA synthetases class-II family profile
Ribosomal RNA adenine methylase transferase N-terminal
Gram-positive cocci surface proteins LPxTG
RNA polymerase sigma factor 70 region 4 type 2
Formamidopyrimidine-DNA glycosylase catalytic
Inosine/uridine-preferring nucleoside hydrolase
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Pyruvate dehydrogenase E1 component middle
Sigma 54 modulation/S30EA ribosomal protein C-terminal
L-seryl-tRNA selenium transferase N-terminal
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Bacterial Ig-like domain-containing protein
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Schiff-base intermediate with acetaldehyde
Positions MEP for the nucleophilic attack
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
NIF system FeS cluster assembly NifU N-terminal
RNA polymerase III subunit RPC82-related helix-turn-helix
Cell wall-binding repeat 2 family protein
Cysteine sulfenic acid (-SOH) intermediate
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Glycine cleavage T-protein C-terminal barrel
Alanyl-transfer RNA synthetases family profile
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Cytochrome C biogenesis protein transmembrane
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Gram-positive pilin subunit D1 N-terminal
Gram-positive pilin subunit D1 N-terminal domain-containing protein
Phosphotransferase system enzyme I N-terminal
Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-? in acceptor proteins)
Sporulation transcription regulator WhiA N-terminal
Alpha-glycerophosphate oxidase C-terminal
Anthranilate synthase component I N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Glycosyltransferase subfamily 4-like N-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
RNA 2-O ribose methyltransferase substrate binding
Small ribosomal subunit protein uS4 N-terminal
Penicillin-binding protein transpeptidase
4'-phosphopantetheinyl transferase N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Tryptophan synthase beta chain-like PALP
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Prokaryotic-type class I peptide chain release factors
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Large ribosomal subunit protein uL6 alpha-beta
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Mandelate racemase/muconate lactonizing enzyme C-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
L,D-transpeptidase catalytic domain-containing protein
RNA binding; important for wobble base 34 recognition
Bacterial bifunctional deaminase-reductase C-terminal
Pyrimidine nucleoside phosphorylase C-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Prepilin type IV endopeptidase peptidase
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Ribose-phosphate pyrophosphokinase N-terminal
ABC transporter substrate-binding protein
Ribosome maturation factor RimP N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Pseudouridine synthase I TruA alpha/beta
Plays an important role in substrate specificity
Helix-hairpin-helix DNA-binding motif class 1
Phosphocysteine intermediate; for EIIB activity
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Putative host cell surface-exposed lipoprotein Ltp-like HTH region
6-phosphogluconate dehydrogenase NADP-binding
Terminase large subunit gp17-like C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Large ribosomal subunit protein uL15/eL18
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
ABC-type glycine betaine transport system substrate-binding
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
CobB/CobQ-like glutamine amidotransferase
PhoD-like phosphatase metallophosphatase
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Electron transfer via tryptophanyl radical
Aconitase A/isopropylmalate dehydratase small subunit swivel
Could play a key role in the communication between the regulatory and the substrate sites
Glycosyl transferase family 3 N-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Peptidase M1 membrane alanine aminopeptidase
Exonuclease VII large subunit C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Endoribonuclease L-PSP/chorismate mutase-like
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Release factor glutamine methyltransferase N-terminal
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Important for substrate specificity; cannot use PPi as phosphoryl donor
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Thymidylate synthase/dCMP hydroxymethylase
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Polymerase/histidinol phosphatase N-terminal
Reversibly protonated during proton transport
Interaction with polymerase core subunit RpoC
Carbamoyl-phosphate synthase small subunit N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Molybdopterin cofactor biosynthesis C (MoaC)
Large ribosomal subunit protein uL2 C-terminal
tRNA(Ile)-lysidine synthase substrate-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Resuscitation-promoting factor Rpf1 C-terminal
Resuscitation-promoting factor core lysozyme-like
DNA-directed RNA polymerase RpoA/D/Rpb3-type
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
Phosphatidate phosphatase APP1 catalytic
Peptide methionine sulphoxide reductase MsrA
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Na+/H+ antiporter MnhB subunit-related protein
Phenol hydroxylase C-terminal dimerisation
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Cell wall-active antibiotics response LiaF-like C-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
O-(5'-phospho-DNA)-tyrosine intermediate
Shikimate dehydrogenase substrate binding N-terminal
Schiff-base intermediate with D-ribose 5-phosphate
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Important for beta-aspartyl-AMP intermediate formation
6-phosphogluconate dehydrogenase C-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
ABC-type glycine betaine transport system substrate-binding domain-containing protein
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Bacterial type II secretion system protein E
Essential for prephenate dehydratase activity