Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Electron transfer flavoprotein alpha/beta-subunit N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Butirosin biosynthesis protein H N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Transposase IS116/IS110/IS902 C-terminal
Urease accessory protein UreH-like transmembrane
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Type I restriction modification DNA specificity
Carbamoyl-phosphate synthase small subunit N-terminal
Arginine decarboxylase C-terminal helical
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Ribosomal RNA small subunit methyltransferase E methyltransferase
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Cytochrome c-552/DMSO reductase-like haem-binding
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Tryptophan synthase beta chain-like PALP
Bacterial type II secretion system protein E
O-(3'-phospho-DNA)-tyrosine intermediate
Gamma-glutamylcyclotransferase AIG2-like
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Type 4 fimbrial biogenesis protein PilX N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Outer membrane lipoprotein-sorting protein
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
TRAP C4-dicarboxylate transport system permease DctM subunit
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Major facilitator superfamily (MFS) profile
Glycosyltransferase subfamily 4-like N-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Aminoacyl-transfer RNA synthetases class-II family profile
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Could be important to modulate the pK values of the two catalytic cysteine residues
Twin-arginine translocation pathway signal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Pyruvate phosphate dikinase AMP/ATP-binding
tRNA pseudouridylate synthase B C-terminal
nitrite reductase (cytochrome; ammonia-forming)
Nitrite/Sulfite reductase ferredoxin-like
Gly-cisPro motif, important for rejection of L-amino acids
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
S-adenosylmethionine-dependent methyltransferase
Arsenosugar biosynthesis radical SAM protein ArsS-like C-terminal
Peptide methionine sulphoxide reductase MsrA
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
NIF system FeS cluster assembly NifU N-terminal
Anthranilate synthase component I N-terminal
Polymerase/histidinol phosphatase N-terminal
Prokaryotic-type class I peptide chain release factors
Sodium/calcium exchanger membrane region
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Dinitrogenase iron-molybdenum cofactor biosynthesis
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Type I restriction enzyme R protein N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:ubiquinone/plastoquinone oxidoreductase chloroplast chain 5 C-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Haem-binding uptake Tiki superfamily ChaN
Aconitase A/isopropylmalate dehydratase small subunit swivel
non-specific serine/threonine protein kinase
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Regulator of nucleoside diphosphate kinase N-terminal
Transcription elongation factor GreA/GreB C-terminal
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Survival protein SurE-like phosphatase/nucleotidase
Alpha-D-phosphohexomutase alpha/beta/alpha
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
RND efflux pump membrane fusion protein barrel-sandwich
Phosphatidic acid phosphatase type 2/haloperoxidase
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Type II secretion system protein GspE N-terminal
Cation-transporting P-type ATPase N-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Essential for prephenate dehydratase activity
YbaK/aminoacyl-tRNA synthetase-associated
Chromosomal replication initiator DnaA C-terminal
Glycoside hydrolase family 57 N-terminal
Outer membrane protein beta-barrel domain-containing protein
Cysteine sulfenic acid (-SOH) intermediate
Activator of Hsp90 ATPase homologue 1-like C-terminal
Helix-hairpin-helix DNA-binding motif class 1
ABC-type glycine betaine transport system substrate-binding
Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Methylene-tetrahydrofolate reductase C-terminal
Reversibly protonated during proton transport
Penicillin-binding protein transpeptidase
Na+/H+ antiporter MnhB subunit-related protein
Pyridoxamine 5'-phosphate oxidase putative
Carboxypeptidase regulatory-like domain-containing protein
High-affinity zinc uptake system protein ZnuA
Important for interaction with partner proteins
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Glycosyl transferase family 3 N-terminal
Proton acceptor; for glutaminase activity
O-(phosphoribosyl dephospho-coenzyme A)serine
Interaction with polymerase core subunit RpoC
N6 adenine-specific DNA methyltransferase N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
5-glutamyl coenzyme A thioester intermediate
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Methionyl-tRNA synthetase anticodon-binding
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Conserved virulence factor B-like winged helix
NADH:ubiquinone oxidoreductase 30kDa subunit
Pyruvate/ketoisovalerate oxidoreductase catalytic
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Cytochrome C biogenesis protein transmembrane
Histidine-specific methyltransferase SAM-dependent
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
N-end rule aminoacyl transferase C-terminal
NIF system FeS cluster assembly NifU C-terminal
TonB-dependent receptor-like beta-barrel
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Pseudouridine synthase I TruA alpha/beta
Pilus formation protein N-terminal domain-containing protein
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
DNA mismatch repair proteins mutS family
Inner membrane protein YgaP-like transmembrane
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
RNA binding; important for wobble base 34 recognition
CobB/CobQ-like glutamine amidotransferase
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Large ribosomal subunit protein uL2 C-terminal
Phosphoribosylformylglycinamidine synthase linker
tRNA (guanine-N(1)-)-methyltransferase C-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
ATPsynthase alpha/beta subunit N-terminal extension
ATP synthase F1 complex delta/epsilon subunit N-terminal
Transcription elongation factor GreA/GreB N-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
Prepilin type IV endopeptidase peptidase
Type II secretion system protein GspC N-terminal
Translation elongation factor P/YeiP central
Important for substrate specificity; cannot use PPi as phosphoryl donor
Plays an important role in substrate specificity
CRISPR-associated protein Cas6 C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Heme-copper oxidase subunit III family profile
Tellurite resistance methyltransferase TehB-like
Periplasmic copper-binding protein NosD beta helix
Sodium symporter small subunit predicted
Cytochrome b561 bacterial/Ni-hydrogenase
Organic solvent tolerance-like N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Alginate export domain-containing protein
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
DNA polymerase III delta subunit C-terminal
Type VI secretion system IcmF C-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-95)
Polysaccharide chain length determinant N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Peptidase M17 leucyl aminopeptidase N-terminal
Type II secretion system protein GspG C-terminal
RNA 2-O ribose methyltransferase substrate binding
Exonuclease VII large subunit C-terminal
3-beta hydroxysteroid dehydrogenase/isomerase
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Membrane fusion protein biotin-lipoyl like
PEP-CTERM protein-sorting domain-containing protein
Large ribosomal subunit protein uL6 alpha-beta
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Positions MEP for the nucleophilic attack
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Nicotinate phosphoribosyltransferase C-terminal
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Mannose-6-phosphate isomerase type II C-terminal
Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant domain-containing protein
Membrane insertase YidC/Oxa/ALB C-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
ABC-type transport auxiliary lipoprotein component
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Right handed beta helix domain-containing protein
Sugar fermentation stimulation protein C-terminal
Cytochrome P460 domain-containing protein
DNA-directed DNA polymerase family A palm
Putative regulatory protein FmdB Zinc ribbon
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Alpha-glycerophosphate oxidase C-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Large ribosomal subunit protein uL15/eL18
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Acetylserotonin O-methyltransferase dimerisation
Peptide methionine sulfoxide reductase MsrA
DNA replication/recombination mediator RecO N-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Type II secretion system protein GspI C-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
YbgF trimerisation domain-containing protein
Increases nucleophilicity of active site Cys
Fibronectin type-III domain-containing protein
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Involved in allosteric activation by GTP
Large ribosomal subunit protein uL30-like ferredoxin-like fold