Large ribosomal subunit protein uL2 C-terminal
Transglutaminase-like domain-containing protein
Membrane fusion protein biotin-lipoyl like
RND efflux pump membrane fusion protein barrel-sandwich
Membrane insertase YidC/Oxa/ALB C-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Major facilitator superfamily (MFS) profile
Translation elongation factor P/YeiP central
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Diacylglycerol glucosyltransferase N-terminal
Glycosyl transferase family 28 C-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Could be important to modulate the pK values of the two catalytic cysteine residues
Large ribosomal subunit protein uL15/eL18
Ribosomal RNA adenine methylase transferase N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
RNA 2-O ribose methyltransferase substrate binding
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Thiamin pyrophosphokinase thiamin-binding
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Pseudouridine synthase I TruA alpha/beta
YbaK/aminoacyl-tRNA synthetase-associated
Putative oxidoreductase/dehydrogenase Rossmann-like
Type II secretion system protein GspG C-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Polymerase/histidinol phosphatase N-terminal
Organic solvent tolerance-like N-terminal
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
RNA binding; important for wobble base 34 recognition
Haem-binding uptake Tiki superfamily ChaN
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Gfo/Idh/MocA-like oxidoreductase N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Threonine/serine exporter-like N-terminal
Tryptophan synthase beta chain-like PALP
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Schiff-base intermediate with substrate; via pyruvic acid
Penicillin-binding protein transpeptidase
Saccharopine dehydrogenase-like C-terminal
Cell envelope-related transcriptional attenuator
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Bacterial type II secretion system protein E
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
DNA replication/recombination mediator RecO N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Could play a key role in the communication between the regulatory and the substrate sites
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Large ribosomal subunit protein uL6 alpha-beta
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Thiamine pyrophosphate enzyme TPP-binding
Type I restriction modification DNA specificity
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Type III restriction enzyme C-terminal endonuclease
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Solute-binding protein family 3/N-terminal
Important for interaction with partner proteins
Glycosyltransferase subfamily 4-like N-terminal
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Chromosomal replication initiator DnaA C-terminal
Ionotropic glutamate receptor C-terminal
DNA-directed DNA polymerase family A palm
Signal recognition particle SRP54 helical bundle
Phosphotransferase system enzyme I N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
6-phosphogluconate dehydrogenase C-terminal
Restriction endonuclease type II DpnII-like
Important for autoinhibition of adenylyltransferase activity
NIF system FeS cluster assembly NifU N-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Alanyl-transfer RNA synthetases family profile
Glycosyl transferase family 8 C-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
DNA mismatch repair proteins mutS family
Glycine cleavage T-protein C-terminal barrel
Reversibly protonated during proton transport
Siroheme decarboxylase AsnC-like ligand binding
Phosphocysteine intermediate; for EIIB activity
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Phosphomannose isomerase type I catalytic
Helix-hairpin-helix DNA-binding motif class 1
Aconitase A/isopropylmalate dehydratase small subunit swivel
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Type I restriction enzyme R protein N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
N6 adenine-specific DNA methyltransferase N-terminal
Glycosyltransferase family 28 N-terminal
Positions MEP for the nucleophilic attack
Pyrimidine nucleoside phosphorylase C-terminal
Prepilin type IV endopeptidase peptidase
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
Proton acceptor; for glutaminase activity
Glycosyl transferase family 3 N-terminal
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Interaction with polymerase core subunit RpoC
TonB-dependent receptor-like beta-barrel
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Release factor glutamine methyltransferase N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Sporulation transcription regulator WhiA N-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Small ribosomal subunit protein uS4 N-terminal
Peptidoglycan recognition protein family
UDP N-acetylglucosamine O-acyltransferase C-terminal
Helix-turn-helix conjugative transposon-like
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Pyridoxamine 5'-phosphate oxidase putative
Cytochrome b561 bacterial/Ni-hydrogenase
Polysaccharide biosynthesis protein C-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Phosphatidylglycerol lysyltransferase C-terminal
Plays an important role in substrate specificity
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
DNA polymerase III delta subunit C-terminal
Dinitrogenase iron-molybdenum cofactor biosynthesis
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Exonuclease VII large subunit C-terminal
Anthranilate synthase component I N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Sporulation stage II protein D amidase enhancer LytB N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Survival protein SurE-like phosphatase/nucleotidase
S-adenosyl-L-homocysteine hydrolase NAD binding
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Lysidine-tRNA(Ile) synthetase C-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic