Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Major facilitator superfamily (MFS) profile
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Schiff-base intermediate with acetaldehyde
Tryptophan synthase beta chain-like PALP
Penicillin-binding protein transpeptidase
Phosphatidic acid phosphatase type 2/haloperoxidase
Ribosomal RNA adenine methylase transferase N-terminal
Choloylglycine hydrolase/NAAA C-terminal
Helix-hairpin-helix DNA-binding motif class 1
Aminoacyl-transfer RNA synthetases class-II family profile
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
RNA binding; important for wobble base 34 recognition
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Pesticidal crystal protein Cry22Aa Ig-like
Polysaccharide biosynthesis protein C-terminal
Type VII secretion system protein EssD-like
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
FAD-dependent oxidoreductase 2 FAD binding
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Reversibly protonated during proton transport
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Important for interaction with partner proteins
Important for autoinhibition of adenylyltransferase activity
Shikimate dehydrogenase substrate binding N-terminal
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Gly-cisPro motif, important for rejection of L-amino acids
Glycosyl hydrolase family 30 beta sandwich
tRNA pseudouridylate synthase B C-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Chromosomal replication initiator DnaA C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
DNA-directed DNA polymerase family A palm
Release factor glutamine methyltransferase N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Pyridoxamine 5'-phosphate oxidase putative
Ribose-phosphate pyrophosphokinase N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
HicB-like antitoxin of toxin-antitoxin system
6-phosphogluconate dehydrogenase C-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
O-(5'-phospho-DNA)-tyrosine intermediate
Conserved virulence factor B-like winged helix
Peptidase M1 membrane alanine aminopeptidase
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Alpha-D-phosphohexomutase alpha/beta/alpha
Glycosyltransferase subfamily 4-like N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Peptide methionine sulphoxide reductase MsrA
YbaK/aminoacyl-tRNA synthetase-associated
Prokaryotic-type class I peptide chain release factors
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Surface layer protein A domain-containing protein
Pseudouridine synthase I TruA alpha/beta
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Involved in allosteric activation by GTP
Alanyl-transfer RNA synthetases family profile
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Thiamin pyrophosphokinase thiamin-binding
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Pyridine nucleotide-disulphide oxidoreductase dimerisation
RNA 2-O ribose methyltransferase substrate binding
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Sporulation transcription regulator WhiA N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Small ribosomal subunit protein uS4 N-terminal
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Pyrimidine nucleoside phosphorylase C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Mandelate racemase/muconate lactonizing enzyme C-terminal
Inosine/uridine-preferring nucleoside hydrolase
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Exonuclease VII large subunit C-terminal
Signal recognition particle SRP54 helical bundle
CobB/CobQ-like glutamine amidotransferase
Thymidylate synthase/dCMP hydroxymethylase
Polymerase/histidinol phosphatase N-terminal
Threonine/serine exporter-like N-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Phosphotransferase system enzyme I N-terminal
Plays an important role in substrate specificity
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Carbamoyl-phosphate synthase small subunit N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
NAD(P) transhydrogenase alpha subunit C-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Important for beta-aspartyl-AMP intermediate formation
Hydroxymethylglutaryl-coenzyme A synthase C-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Peptidase S9 prolyl oligopeptidase catalytic
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Glycosyl transferase family 3 N-terminal
Cation-transporting P-type ATPase N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
ABC-type glycine betaine transport system substrate-binding
DNA replication/recombination mediator RecO N-terminal
Sugar fermentation stimulation protein C-terminal
Translation elongation factor P/YeiP central
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase