Pyridine nucleotide-disulphide oxidoreductase dimerisation
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
Polymerase/histidinol phosphatase N-terminal
Prokaryotic-type class I peptide chain release factors
3-beta hydroxysteroid dehydrogenase/isomerase
Type 4 fimbrial biogenesis protein PilX N-terminal
Important for interaction with partner proteins
Type II secretion system protein GspE N-terminal
Solute-binding protein family 3/N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Adaptive response protein AidB N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Ribosomal RNA adenine methylase transferase N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Transposase IS116/IS110/IS902 C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Acyl-CoA dehydrogenase/oxidase N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Right handed beta helix domain-containing protein
Glycosyltransferase subfamily 4-like N-terminal
Interaction with polymerase core subunit RpoC
Disulphide bond isomerase DsbC/G N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
O-(5'-phospho-DNA)-tyrosine intermediate
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Beta-lactamase-related domain-containing protein
Aminoacyl-transfer RNA synthetases class-II family profile
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Phosphotransferase system enzyme I N-terminal
Na+/H+ antiporter MnhB subunit-related protein
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Outer membrane protein assembly factor BamA
Alpha-D-phosphohexomutase alpha/beta/alpha
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Alanyl-transfer RNA synthetases family profile
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
ABC-type transport auxiliary lipoprotein component
Sodium symporter small subunit predicted
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Arsenosugar biosynthesis radical SAM protein ArsS-like C-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Chromosomal replication initiator protein DnaA
RND efflux pump membrane fusion protein barrel-sandwich
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
TonB-dependent receptor-like beta-barrel
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Outer membrane lipoprotein-sorting protein
Pyruvate dehydrogenase E1 component middle
Cytochrome b561 bacterial/Ni-hydrogenase
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Outer membrane protein assembly factor BamB
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Leucine-rich repeat-containing N-terminal plant-type domain-containing protein
Peptidase S9 prolyl oligopeptidase catalytic
SUF system FeS cluster assembly SufBD N-terminal
NIF system FeS cluster assembly NifU C-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Mannose-6-phosphate isomerase type II C-terminal
Endolytic peptidoglycan transglycosylase RlpA
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Amidohydrolase-related domain-containing protein
Plays an important role in substrate specificity
Glycine cleavage T-protein C-terminal barrel
Thiol:disulfide interchange protein DsbD
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Phosphoadenosine phosphosulphate reductase
Gamma-butyrobetaine hydroxylase-like N-terminal
Ysc84 actin-binding domain-containing protein
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Putative regulatory protein FmdB Zinc ribbon
Cysteine sulfenic acid (-SOH) intermediate
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Bacterial Ig-like domain-containing protein
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
Type II secretion system protein GspC N-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Polysaccharide chain length determinant N-terminal
Outer membrane protein assembly factor BamE
S-adenosylmethionine-dependent methyltransferase
Heme-copper oxidase subunit III family profile
Penicillin-binding protein transpeptidase
Large ribosomal subunit protein uL2 C-terminal
Pyrimidine nucleoside phosphorylase C-terminal
IPTL-CTERM protein sorting domain-containing protein
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein
Threonine/serine exporter-like N-terminal
Bacterial type II secretion system protein E
Tryptophan synthase beta chain-like PALP
Pyruvate phosphate dikinase AMP/ATP-binding
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Peptidase C-terminal archaeal/bacterial domain-containing protein
Small ribosomal subunit protein uS4 N-terminal
Cation-transporting P-type ATPase N-terminal
Glucose-methanol-choline oxidoreductase N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Translation elongation factor P/YeiP central
Glycosyl transferase family 3 N-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Membrane fusion protein biotin-lipoyl like
Helix-hairpin-helix DNA-binding motif class 1
Type II secretion system protein GspG C-terminal
Abnormal spindle-like microcephaly-associated protein ASH domain-containing protein
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Regulator of nucleoside diphosphate kinase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Could be important to modulate the pK values of the two catalytic cysteine residues
Cytochrome c-type biogenesis protein CcmE
RNA 2-O ribose methyltransferase substrate binding
Peptidase M12B domain-containing protein
ATP synthase F1 complex delta/epsilon subunit N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Abnormal spindle-like microcephaly-associated protein ASH
NADH:ubiquinone oxidoreductase intermediate-associated protein 30
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Curli production assembly/transport component CsgG
Urease accessory protein UreH-like transmembrane
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Gly-cisPro motif, important for rejection of L-amino acids
Trigger factor ribosome-binding bacterial
DNA replication/recombination mediator RecO N-terminal
Peptide methionine sulphoxide reductase MsrA
Chromosomal replication initiator DnaA C-terminal
Blue (type 1) copper domain-containing protein
Transition state stabilizer; via amide nitrogen
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Prepilin type IV endopeptidase peptidase
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Proton acceptor; for glutaminase activity
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Sodium/calcium exchanger membrane region
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
ATP-dependent DNA helicase RecG C-terminal
SMP-30/Gluconolactonase/LRE-like region domain-containing protein
Ribose-phosphate pyrophosphokinase N-terminal
Tail specific protease domain-containing protein
Beta-lactamase hydrolase-like protein phosphatase-like
Beta-lactamase hydrolase-like protein phosphatase-like domain-containing protein
DNA-directed DNA polymerase family A palm
Peptidase MA-like domain-containing protein
Transposase IS204/IS1001/IS1096/IS1165 DDE
Transposase IS204/IS1001/IS1096/IS1165 helix-turn-helix
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Pseudouridine synthase I TruA alpha/beta
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Cytochrome C Planctomycete-type domain-containing protein
DNA mismatch repair proteins mutS family
Peptidase M14 carboxypeptidase A domain-containing protein
Lysidine-tRNA(Ile) synthetase C-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Photosynthesis system II assembly factor Ycf48/Hcf136-like domain-containing protein
HicB-like antitoxin of toxin-antitoxin system
Type II secretion system protein GspI C-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
DNA polymerase III subunit delta C-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
May play a role in metal incorporation in vivo
May play a role in transmitting local conformational changes
Choice-of-anchor D domain-containing protein
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Membrane transport protein MMPL domain-containing protein
Acyl-CoA dehydrogenase C-terminal bacterial-type
Release factor glutamine methyltransferase N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Isocitrate dehydrogenase kinase/phosphatase (AceK) kinase
Isocitrate dehydrogenase kinase/phosphatase (AceK) regulatory
Cytochrome c-type biogenesis protein CcmF C-terminal
Carboxypeptidase regulatory-like domain-containing protein
NADH:ubiquinone oxidoreductase 30kDa subunit
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Calcineurin-like phosphoesterase C-terminal
Calcineurin-like phosphoesterase N-terminal
CASTOR/POLLUX/SYM8 ion channel conserved
Important for beta-aspartyl-AMP intermediate formation
Histidine-specific methyltransferase SAM-dependent
Reversibly protonated during proton transport
Transglycosylase SLT domain-containing protein
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Endonuclease/exonuclease/phosphatase domain-containing protein
Biopterin-dependent aromatic amino acid hydroxylase family profile
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Inner membrane protein YgaP-like transmembrane
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Extradiol ring-cleavage dioxygenase LigAB LigA subunit
Ribulose bisphosphate carboxylase large subunit C-terminal
Cytochrome c-552/4 domain-containing protein
Aminoacyl-tRNA synthetase class I anticodon-binding
Bacterial repeat domain-containing protein
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
N6 adenine-specific DNA methyltransferase N-terminal
Polysaccharide biosynthesis protein CapD-like
Thymidylate synthase/dCMP hydroxymethylase
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
RNA binding; important for wobble base 34 recognition
Membrane insertase YidC/Oxa/ALB C-terminal