Pyridoxamine 5'-phosphate oxidase putative
Thiamin pyrophosphokinase thiamin-binding
Cell envelope-related transcriptional attenuator
Aminoacyl-transfer RNA synthetases class-II family profile
Large ribosomal subunit protein uL6 alpha-beta
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Lysidine-tRNA(Ile) synthetase C-terminal
Phosphomannose isomerase type I catalytic
Nickel transport complex, NikM subunit, transmembrane
DNA replication/recombination mediator RecO N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Translation elongation factor P/YeiP central
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Major facilitator superfamily (MFS) profile
Release factor glutamine methyltransferase N-terminal
Polypeptide-transport-associated ShlB-type
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Pyrimidine nucleoside phosphorylase C-terminal
Mannose-6-phosphate isomerase type II C-terminal
Phospholipase D-like domain-containing protein
NIF system FeS cluster assembly NifU N-terminal
tRNA-specific 2-thiouridylase MnmA-like central
tRNA pseudouridylate synthase B C-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Glycosyl transferase family 28 C-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Important for autoinhibition of adenylyltransferase activity
Gamma-glutamylcyclotransferase AIG2-like
ABC transporter substrate-binding protein PnrA-like
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Phosphatidic acid phosphatase type 2/haloperoxidase
Large ribosomal subunit protein uL15/eL18
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Cation-transporting P-type ATPase N-terminal
TtsA-like Glycoside hydrolase family 108
HicB-like antitoxin of toxin-antitoxin system
Polymerase/histidinol phosphatase N-terminal
Plays an important role in discriminating NADH against NADPH
Membrane insertase YidC/Oxa/ALB C-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Phosphocysteine intermediate; for EIIB activity
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
1,4-alpha-glucan branching enzyme C-terminal
Glycoside hydrolase family 57 N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Cytochrome C biogenesis protein transmembrane
Pyruvate phosphate dikinase AMP/ATP-binding
YbaK/aminoacyl-tRNA synthetase-associated
Gfo/Idh/MocA-like oxidoreductase N-terminal
Important for guanine/8-oxoguanine distinction
Schiff-base intermediate with acetaldehyde
Tryptophan synthase beta chain-like PALP
Aspartate/homoserine dehydrogenase NAD-binding
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Hydroxymethylglutaryl-coenzyme A synthase C-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
Shikimate dehydrogenase substrate binding N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
C-type lysozyme inhibitor domain-containing protein
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
ATP-dependent DNA helicase RecG C-terminal
Small ribosomal subunit protein uS4 N-terminal
SUF system FeS cluster assembly SufBD N-terminal
Interaction with polymerase core subunit RpoC
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
Pseudouridine synthase I TruA alpha/beta
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Alanyl-transfer RNA synthetases family profile
Ribose-phosphate pyrophosphokinase N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
CobB/CobQ-like glutamine amidotransferase
Plays an important role in substrate specificity
Aconitase A/isopropylmalate dehydratase small subunit swivel
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
RlpA-like protein double-psi beta-barrel
Glucosamine/galactosamine-6-phosphate isomerase
Increases nucleophilicity of active site Cys
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Schiff-base intermediate with substrate; via pyruvic acid
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Large ribosomal subunit protein uL2 C-terminal
Reversibly protonated during proton transport
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Cysteine sulfenic acid (-SOH) intermediate
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Prokaryotic-type class I peptide chain release factors
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Outer membrane protein beta-barrel domain-containing protein
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Large ribosomal subunit protein bL9 C-terminal
DNA mismatch repair proteins mutS family
Organic solvent tolerance-like N-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Resolvase/invertase-type recombinase catalytic
Exonuclease VII large subunit C-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Bacterial transcription activator effector binding
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Chromosomal replication initiator DnaA C-terminal
RNA 2-O ribose methyltransferase substrate binding
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Polysaccharide lyase 8 N-terminal alpha-helical
Polysaccharide lyase family 8 C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Penicillin-binding protein transpeptidase
LytR/CpsA/Psr regulator C-terminal domain-containing protein
ssDNA thymidine ADP-ribosyltransferase DarT
Autotransporter domain-containing protein
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Phage terminase large subunit C-terminal
Phage terminase large subunit N-terminal
tRNA (guanine-N(1)-)-methyltransferase C-terminal
RNA binding; important for wobble base 34 recognition
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Glycosyltransferase family 28 N-terminal
3-beta hydroxysteroid dehydrogenase/isomerase
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
N-sulphoglucosamine sulphohydrolase C-terminal
Lacto-N-biose phosphorylase-like N-terminal TIM barrel
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
tRNA-specific 2-thiouridylase MnmA-like C-terminal
Phosphotransferase system enzyme I N-terminal
Essential for prephenate dehydratase activity
ABC transporter substrate binding protein
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Could play a key role in the communication between the regulatory and the substrate sites
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Sugar fermentation stimulation protein C-terminal
Helix-hairpin-helix DNA-binding motif class 1
N6 adenine-specific DNA methyltransferase N-terminal
Inosine/uridine-preferring nucleoside hydrolase
DNA-directed DNA polymerase family A palm
Nicotinamide phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase