ATP-dependent DNA helicase RecG C-terminal
Aspartate/homoserine dehydrogenase NAD-binding
Mannose-6-phosphate isomerase type II C-terminal
tRNA pseudouridylate synthase B C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Phosphocysteine intermediate; for EIIB activity
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Alpha-D-phosphohexomutase alpha/beta/alpha
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Glycosyl hydrolase-like 10 domain-containing protein
Alanyl-transfer RNA synthetases family profile
Gly-cisPro motif, important for rejection of L-amino acids
Aconitase A/isopropylmalate dehydratase small subunit swivel
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Pyridine nucleotide-disulphide oxidoreductase dimerisation
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Schiff-base intermediate with dihydroxyacetone-P
Important for autoinhibition of adenylyltransferase activity
Phosphatidic acid phosphatase type 2/haloperoxidase
ABC transporter substrate-binding protein PnrA-like
Polymerase/histidinol phosphatase N-terminal
Esterase Ig-like N-terminal domain-containing protein
Polypeptide-transport-associated ShlB-type
ABC transporter substrate binding protein
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
Aminoacyl-transfer RNA synthetases class-II family profile
Lysozyme inhibitor LprI N-terminal domain-containing protein
DNA mismatch repair proteins mutS family
Glycosyltransferase subfamily 4-like N-terminal
Peptide methionine sulphoxide reductase MsrA
Cytochrome C biogenesis protein transmembrane
Saccharopine dehydrogenase-like C-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Cell envelope-related transcriptional attenuator
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
TtsA-like Glycoside hydrolase family 108
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Outer membrane protein beta-barrel domain-containing protein
Polysaccharide biosynthesis protein C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
AB hydrolase-1 domain-containing protein
Schiff-base intermediate with acetaldehyde
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
UDP N-acetylglucosamine O-acyltransferase C-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Essential for prephenate dehydratase activity
DNA replication/recombination mediator RecO N-terminal
Membrane fusion protein biotin-lipoyl like
RND efflux pump membrane fusion protein barrel-sandwich
Penicillin-binding protein transpeptidase
Helix-hairpin-helix DNA-binding motif class 1
Reversibly protonated during proton transport
Phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease 3
DNA-directed RNA polymerase RpoA/D/Rpb3-type
C-type lysozyme inhibitor domain-containing protein
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
RNA binding; important for wobble base 34 recognition
CobB/CobQ-like glutamine amidotransferase
Gfo/Idh/MocA-like oxidoreductase N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Could play a key role in the communication between the regulatory and the substrate sites
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Solute-binding protein family 3/N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
FAD-dependent oxidoreductase 2 FAD binding
Large ribosomal subunit protein uL6 alpha-beta
Large ribosomal subunit protein uL30-like ferredoxin-like fold
YbaK/aminoacyl-tRNA synthetase-associated
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
tRNA (guanine-N(1)-)-methyltransferase C-terminal
Resolvase/invertase-type recombinase catalytic
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Pyrimidine nucleoside phosphorylase C-terminal
DNA-directed DNA polymerase family A palm
Large ribosomal subunit protein bL9 C-terminal
Interaction with polymerase core subunit RpoC
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Could be important to modulate the pK values of the two catalytic cysteine residues
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Organic solvent tolerance-like N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase N-terminal
Chromosomal replication initiator DnaA C-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Heat-inducible transcription repressor HrcA C-terminal
Shikimate dehydrogenase substrate binding N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Phosphotransferase system enzyme I N-terminal
Large ribosomal subunit protein uL15/eL18
NIF system FeS cluster assembly NifU N-terminal
Nitrite/Sulfite reductase ferredoxin-like
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Release factor glutamine methyltransferase N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Thiamin pyrophosphokinase thiamin-binding
Gfo/Idh/MocA-like oxidoreductase C-terminal
Tryptophan synthase beta chain-like PALP
HicB-like antitoxin of toxin-antitoxin system
Phosphoadenosine phosphosulphate reductase
Plays an important role in discriminating NADH against NADPH
RNA 2-O ribose methyltransferase substrate binding
Pseudouridine synthase I TruA alpha/beta
Large ribosomal subunit protein uL2 C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Cation-transporting P-type ATPase N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Peptidase S9 prolyl oligopeptidase catalytic
Phosphomannose isomerase type I catalytic
Ionotropic glutamate receptor C-terminal
Type III restriction/modification enzyme methylation subunit
1,4-alpha-glucan branching enzyme C-terminal
Glycoside hydrolase family 57 N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Cobalamin-independent methionine synthase MetE N-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Pyruvate phosphate dikinase AMP/ATP-binding
Small ribosomal subunit protein uS4 N-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Sugar fermentation stimulation protein C-terminal
Prepilin type IV endopeptidase peptidase
Increases nucleophilicity of active site Cys
Phosphoribosylformylglycinamidine synthase linker
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Ribosomal RNA adenine methylase transferase N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Plays an important role in substrate specificity
Translation elongation factor P/YeiP central
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Lysidine-tRNA(Ile) synthetase C-terminal
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Thymidylate synthase/dCMP hydroxymethylase
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
Prokaryotic-type class I peptide chain release factors
Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY
Membrane insertase YidC/Oxa/ALB C-terminal
Cysteine sulfenic acid (-SOH) intermediate