Resuscitation-promoting factor Rpf1 C-terminal
Resuscitation-promoting factor core lysozyme-like
Peptidoglycan recognition protein family
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Anthranilate synthase component I N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Formamidopyrimidine-DNA glycosylase catalytic
Ribose-phosphate pyrophosphokinase N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Threonine/serine exporter-like N-terminal
Phosphocysteine intermediate; for EIIB activity
Molybdopterin cofactor biosynthesis C (MoaC)
Alpha-D-phosphohexomutase alpha/beta/alpha
Inosine/uridine-preferring nucleoside hydrolase
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
6-phosphogluconate dehydrogenase C-terminal
Phosphoribosylformylglycinamidine synthase linker
Phosphatidate phosphatase APP1 catalytic
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Major facilitator superfamily (MFS) profile
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Involved in ionization of N3 of dUMP, leading to its activation
Penicillin-binding protein transpeptidase
YbaK/aminoacyl-tRNA synthetase-associated
Interaction with polymerase core subunit RpoC
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cysteine sulfenic acid (-SOH) intermediate
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
tRNA(Ile)-lysidine synthase substrate-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
O-(5'-phospho-DNA)-tyrosine intermediate
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Prokaryotic-type class I peptide chain release factors
O-(3'-phospho-DNA)-tyrosine intermediate
Membrane insertase YidC/Oxa/ALB C-terminal
Positions MEP for the nucleophilic attack
Gram-positive cocci surface proteins LPxTG
Gram-positive cocci surface proteins LPxTG domain-containing protein
Nitrite/Sulfite reductase ferredoxin-like
Sigma 54 modulation/S30EA ribosomal protein C-terminal
RNA 2-O ribose methyltransferase substrate binding
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
TetR transcriptional regulator CgmR-like C-terminal
Peptidase M1 membrane alanine aminopeptidase
Peptidase S9 prolyl oligopeptidase catalytic
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Small ribosomal subunit protein uS4 N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Putative regulatory protein FmdB Zinc ribbon
DNA replication/recombination mediator RecO N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Na+/H+ antiporter MnhB subunit-related protein
Could be important to modulate the pK values of the two catalytic cysteine residues
Ribosome maturation factor RimP N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Chromosomal replication initiator DnaA C-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Cell wall-active antibiotics response LiaF-like C-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
BAAT/Acyl-CoA thioester hydrolase C-terminal
DNA polymerase III delta subunit C-terminal
NIF system FeS cluster assembly NifU N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Aminoacyl-transfer RNA synthetases class-II family profile
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Phosphoadenosine phosphosulphate reductase
RNA polymerase sigma factor 70 region 4 type 2
Putative host cell surface-exposed lipoprotein Ltp-like HTH region
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Helix-hairpin-helix DNA-binding motif class 1
SUF system FeS cluster assembly SufBD N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Endoribonuclease L-PSP/chorismate mutase-like
Phosphotransferase system enzyme I N-terminal
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
ATP-dependent DNA helicase RecG C-terminal
Phosphomannose isomerase type I catalytic
Large ribosomal subunit protein uL15/eL18
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Glycosyltransferase subfamily 4-like N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
PhoD-like phosphatase metallophosphatase
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Putative Flp pilus-assembly TadG-like N-terminal
CobB/CobQ-like glutamine amidotransferase
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Peptide methionine sulphoxide reductase MsrA
Large ribosomal subunit protein uL6 alpha-beta
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Thiamine pyrophosphate enzyme TPP-binding
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Cytochrome C biogenesis protein transmembrane
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
Pyruvate dehydrogenase E1 component middle
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Tryptophan synthase beta chain-like PALP
Essential for prephenate dehydratase activity
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Glycine cleavage T-protein C-terminal barrel
Carbamoyl-phosphate synthase small subunit N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Polymerase/histidinol phosphatase N-terminal
Cytochrome b/b6 N-terminal region profile
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Important for substrate specificity; cannot use PPi as phosphoryl donor
Release factor glutamine methyltransferase N-terminal
RNA binding; important for wobble base 34 recognition
Prepilin type IV endopeptidase peptidase
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Large ribosomal subunit protein uL2 C-terminal
Nucleophile; cysteine thiosulfonate intermediate
Alanyl-transfer RNA synthetases family profile
Resolvase/invertase-type recombinase catalytic
Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-? in acceptor proteins)
Reversibly protonated during proton transport
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
4'-phosphopantetheinyl transferase N-terminal
Schiff-base intermediate with D-ribose 5-phosphate
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Nicotinate phosphoribosyltransferase N-terminal
NADH-rubredoxin oxidoreductase C-terminal
Important for beta-aspartyl-AMP intermediate formation
Translation elongation factor P/YeiP central
Bacterial type II secretion system protein E
Plays an important role in substrate specificity
Exonuclease VII large subunit C-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Gram-positive pilin subunit D1 N-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Glycosyl transferase family 3 N-terminal
Cobalamin-independent methionine synthase MetE N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Gly-cisPro motif, important for rejection of L-amino acids