Thiol:disulfide interchange protein DsbL
Tryptophan synthase beta chain-like PALP
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Aspartate/homoserine dehydrogenase NAD-binding
Glycosyltransferase subfamily 4-like N-terminal
Phosphoadenosine phosphosulphate reductase
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Translation elongation factor P/YeiP central
Mandelate racemase/muconate lactonizing enzyme C-terminal
Glycosyl transferase family 8 C-terminal
Type III secretion system flagellar brake protein YcgR PilZN
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Involved in proton transfer during cleavage
NADH:ubiquinone oxidoreductase 30kDa subunit
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
O-(5'-phospho-DNA)-tyrosine intermediate
Major facilitator superfamily (MFS) profile
Lytic transglycosylase superhelical linker
RND efflux pump membrane fusion protein barrel-sandwich
Transcription factor NikR nickel binding C-terminal
Heme-copper oxidase subunit III family profile
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Periplasmic binding protein/LacI sugar binding
The binding site for the sugar molecule has not yet been established, but C-87 may be involved
Aminoacyl-transfer RNA synthetases class-II family profile
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Transcriptional regulator SgrR N-terminal HTH
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Greasy slide, important in sugar transport
O-(3'-phospho-DNA)-tyrosine intermediate
Flagellar motor switch protein FliN-like C-terminal
Regulator of nucleoside diphosphate kinase N-terminal
Transcription elongation factor GreA/GreB C-terminal
Sugar fermentation stimulation protein C-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
Spy/CpxP family protein refolding chaperone
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Glutathionylspermidine synthase pre-ATP-grasp-like
Quercetin 2,3-dioxygenase C-terminal cupin
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Outer membrane protein assembly factor BamA
ABC-type transport auxiliary lipoprotein component
Mannose-6-phosphate isomerase type II C-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Thiol:disulfide interchange protein DsbD
Outer-membrane lipoprotein carrier protein
Important for beta-aspartyl-AMP intermediate formation
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
DNA mismatch repair MutH/Type II restriction enzyme Sau3AI
Important for interaction with partner proteins
RNA polymerase sigma factor 70 region 4 type 2
Thymidylate synthase/dCMP hydroxymethylase
Involved in allosteric activation by GTP
Interacts with tRNA; defines subfamily-specific binding signature
Cytochrome b561 bacterial/Ni-hydrogenase
Penicillin-binding protein transpeptidase
Sodium/calcium exchanger membrane region
Plays an important role in substrate specificity
Nitrite/Sulfite reductase ferredoxin-like
Curli production assembly/transport component CsgG
Membrane insertase YidC/Oxa/ALB C-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Threonine/serine exporter-like N-terminal
Bacterial transcription activator effector binding
Polymerase/histidinol phosphatase N-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Mechanosensitive ion channel inner membrane
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Non-canonical purine NTP phosphatase/PRRC1
Chromosome partition protein MukF C-terminal
Chromosome partition protein MukF middle
Chromosome partition protein MukF winged-helix
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
Pyridine nucleotide-disulphide oxidoreductase dimerisation
CobB/CobQ-like glutamine amidotransferase
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Polysaccharide chain length determinant N-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
D-galactose/methyl-galactoside binding periplasmic protein MglB
Chromosomal replication initiator DnaA C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Pyruvate phosphate dikinase AMP/ATP-binding
Phosphocysteine intermediate; for EIIB activity
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Mediates proton transfer from the outer aqueous phase to the interior of the protein; involved in linking H(+) and Cl(-) transport
Mediates proton transfer from the protein to the inner aqueous phase
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Prepilin peptidase dependent protein C-like C-terminal
Large ribosomal subunit protein uL15/eL18
Tetrahydrodipicolinate-N-succinyltransferase chain A
TonB-dependent receptor-like beta-barrel
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Phosphatidic acid phosphatase type 2/haloperoxidase
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Calcium/calmodulin-dependent protein kinase II association-domain
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Gfo/Idh/MocA-like oxidoreductase N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Prokaryotic-type class I peptide chain release factors
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
Pseudouridine synthase I TruA alpha/beta
DNA-3-methyladenine glycosylase AlkA N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Alanyl-transfer RNA synthetases family profile
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Small ribosomal subunit protein uS4 N-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Glycine cleavage T-protein C-terminal barrel
Peptidase S9 prolyl oligopeptidase catalytic
Could play a key role in the communication between the regulatory and the substrate sites
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Pyrimidine nucleoside phosphorylase C-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Membrane fusion protein biotin-lipoyl like
NIF system FeS cluster assembly NifU N-terminal
Penicillin-binding protein activator LpoB
Aldehyde ferredoxin oxidoreductase N-terminal
Outer membrane protein assembly factor BamE
Essential for prephenate dehydratase activity
O-(phosphoribosyl dephospho-coenzyme A)serine
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Large ribosomal subunit protein bL25 L25
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Interaction with polymerase core subunit RpoC
RNA 2-O ribose methyltransferase substrate binding
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Gly-cisPro motif, important for rejection of L-amino acids
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Glycosyl transferase family 3 N-terminal
Outer membrane protein assembly factor BamB
NIF system FeS cluster assembly NifU C-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Membrane-bound lytic murein transglycosylase A
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Inosine/uridine-preferring nucleoside hydrolase
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Curli production assembly/transport component CsgF
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Periplasmic nitrate reductase, electron transfer subunit
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Nucleoside-specific channel-forming protein Tsx
Essential for degradation by Lon protease
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Cysteine sulfenic acid (-SOH) intermediate
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Curli production assembly/transport component CsgE
Moves into active site upon enzyme activation, plays a role in electron transfer
Capsule biosynthesis GfcC-like C-terminal
Capsule biosynthesis GfcC-like N-terminal
Required for dimer formation and molybdate binding
Nucleophile; cysteine thiosulfonate intermediate
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Cob(I)alamin adenosyltransferase N-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Transcription elongation factor GreA/GreB N-terminal
Important for substrate binding and specificity
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Tellurite resistance methyltransferase TehB-like
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Guanylate kinase/L-type calcium channel beta subunit
Pyruvate dehydrogenase E1 component middle
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
DNA polymerase III delta subunit C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Involved in tetramerization or stability of the tetramer
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Ion-translocating oxidoreductase complex subunit G
RNA binding; important for wobble base 34 recognition
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Prepilin type IV endopeptidase peptidase
Methylguanine DNA methyltransferase ribonuclease-like
DnaJ homologue subfamily C member 28 conserved
Gfo/Idh/MocA-like oxidoreductase C-terminal
High-affinity zinc uptake system protein ZnuA
Flagella basal body P-ring formation protein FlgA
Positions MEP for the nucleophilic attack
SUF system FeS cluster assembly SufBD N-terminal
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Superoxide dismutase copper/zinc binding
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
ABC-type glycine betaine transport system substrate-binding
Outer membrane protein assembly factor BamD
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Major facilitator superfamily associated
Reversibly protonated during proton transport
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Flagellar motor switch protein FliN N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
6-phosphogluconate dehydrogenase C-terminal
Appears to be important in orienting the phosphate for catalysis
Bacterial type II secretion system protein E
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
Gamma-glutamylcyclotransferase AIG2-like
Acyl-ester intermediate; for transpeptidase activity
Proton donor; for transglycosylase activity
Transglycosylase PBP1b N-terminal transmembrane
Large ribosomal subunit protein uL2 C-terminal
Arginine decarboxylase C-terminal helical
Helix-hairpin-helix DNA-binding motif class 1
Alpha-glycerophosphate oxidase C-terminal
DNA polymerase III subunit delta C-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Integral membrane protein YccS N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
TRAP C4-dicarboxylate transport system permease DctM subunit
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Large ribosomal subunit protein uL6 alpha-beta
Anthranilate synthase component I N-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
Glucosamine/galactosamine-6-phosphate isomerase
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Outer-membrane lipoprotein Wza C-terminal