Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
N-acetylmuramoyl-L-alanine amidase domain-containing protein
ABC transporter substrate-binding protein
Major facilitator superfamily (MFS) profile
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
Tryptophan synthase beta chain-like PALP
TonB-dependent receptor-like beta-barrel
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Sodium symporter small subunit predicted
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Peptidase S9 prolyl oligopeptidase catalytic
Cupin 2 conserved barrel domain-containing protein
Peptidase S8/S53 domain-containing protein
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Important for beta-aspartyl-AMP intermediate formation
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Methyltransferase type 11 domain-containing protein
Heme-copper oxidase subunit III family profile
Penicillin-binding protein transpeptidase
Chromosomal replication initiator protein DnaA
Interaction with polymerase core subunit RpoC
Polymerase/histidinol phosphatase N-terminal
TonB C-terminal domain-containing protein
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Reversibly protonated during proton transport
Aminoacyl-transfer RNA synthetases class-II family profile
Flagellar assembly protein FliH/Type III secretion system HrpE
Solute-binding protein family 3/N-terminal
Solute-binding protein family 3/N-terminal domain-containing protein
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Aspartate/homoserine dehydrogenase NAD-binding
Glycosyl-hydrolase family 116 N-terminal
Glycosyl-hydrolase family 116 catalytic region
Isopenicillin N synthase-like Fe(2+) 2OG dioxygenase
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Glycine cleavage T-protein C-terminal barrel
RNA polymerase sigma factor 70 region 4 type 2
Cysteine sulfenic acid (-SOH) intermediate
Glycosyltransferase subfamily 4-like N-terminal
NIF system FeS cluster assembly NifU N-terminal
Survival protein SurE-like phosphatase/nucleotidase
Carboxypeptidase regulatory-like domain-containing protein
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Amidohydrolase-related domain-containing protein
Metallo-beta-lactamase domain-containing protein
O-(3'-phospho-DNA)-tyrosine intermediate
Type 4 fimbrial biogenesis protein PilX N-terminal
Moybdenum cofactor oxidoreductase dimerisation
Gly-cisPro motif, important for rejection of L-amino acids
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Plays an important role in substrate specificity
Glucosamine/galactosamine-6-phosphate isomerase
Shikimate dehydrogenase substrate binding N-terminal
Prokaryotic-type class I peptide chain release factors
DNA-directed RNA polymerase subunit delta
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Pyrimidine nucleoside phosphorylase C-terminal
Important for interaction with partner proteins
Could be important to modulate the pK values of the two catalytic cysteine residues
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
Inner membrane protein YgaP-like transmembrane
RND efflux pump membrane fusion protein barrel-sandwich
RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Flagellar hook-length control protein-like C-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
Outer membrane protein beta-barrel domain-containing protein
Phosphoadenosine phosphosulphate reductase
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
ABC transmembrane type-1 domain-containing protein
Proline utilization A proline dehydrogenase N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
TIGR03016 family PEP-CTERM system-associated outer membrane protein
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Acyl-ester intermediate; for transpeptidase activity
Proton donor; for transglycosylase activity
High potential iron-sulfur proteins family profile
DNA polymerase III subunit delta C-terminal
Beta-lactamase-related domain-containing protein
Divergent polysaccharide deacetylase family protein
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
O-(5'-phospho-DNA)-tyrosine intermediate
Exonuclease VII large subunit C-terminal
7 transmembrane helices usually fused to an inactive transglutaminase
Inactive transglutaminase fused to 7 transmembrane helices
Nuclear transport factor 2 family protein
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Ribose-phosphate pyrophosphokinase N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
PEP-CTERM protein-sorting domain-containing protein
Regulator of nucleoside diphosphate kinase N-terminal
Transcription elongation factor GreA/GreB C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Large ribosomal subunit protein uL2 C-terminal
Ysc84 actin-binding domain-containing protein
Chromosomal replication initiator DnaA C-terminal
Outer membrane lipoprotein BamD-like domain-containing protein
GlyGly-CTERM sorting domain-containing protein
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
SUF system FeS cluster assembly SufBD N-terminal
Type IV secretion system coupling protein TraD DNA-binding
Amidohydrolase 3 domain-containing protein
TonB-dependent receptor-like beta-barrel domain-containing protein
Large ribosomal subunit protein uL30-like ferredoxin-like fold
t-SNARE coiled-coil homology domain-containing protein
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Gamma-butyrobetaine hydroxylase-like N-terminal
Peptidase M14 carboxypeptidase A domain-containing protein
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Tetrahydrodipicolinate-N-succinyltransferase chain A
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Nitrite/Sulfite reductase ferredoxin-like
Pyruvate phosphate dikinase AMP/ATP-binding
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
RNA 2-O ribose methyltransferase substrate binding
Serine aminopeptidase S33 domain-containing protein
Dystroglycan-type cadherin-like domain-containing protein
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Outer membrane protein assembly factor BamD
Aminotransferase class I/classII domain-containing protein
Sortilin N-terminal domain-containing protein
Bacterial type II secretion system protein E
Fibronectin type-III domain-containing protein
N6 adenine-specific DNA methyltransferase N-terminal
DNA replication/recombination mediator RecO N-terminal
2-oxoisovalerate dehydrogenase E1 alpha subunit N-terminal
Glycosyl transferase family 3 N-terminal
6-phosphogluconate dehydrogenase C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Disulphide bond isomerase DsbC/G N-terminal
Type II secretion system protein GspI C-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
PhoD-like phosphatase metallophosphatase
Translocation and assembly module subunit TamA
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
AB hydrolase-1 domain-containing protein
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
PsbP C-terminal domain-containing protein
L,D-transpeptidase catalytic domain-containing protein
Cytochrome c-type biogenesis protein CcmF C-terminal
Pseudouridine synthase I TruA alpha/beta
Cytochrome b561 bacterial/Ni-hydrogenase
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Small ribosomal subunit protein uS4 N-terminal
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-106)
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Thymidylate synthase/dCMP hydroxymethylase
DNA mismatch repair proteins mutS family
Glycine zipper 2TM domain-containing protein
Acyl-CoA dehydrogenase C-terminal bacterial-type
PHA accumulation regulator DNA-binding N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Mannose-6-phosphate isomerase type II C-terminal
Sodium/calcium exchanger membrane region
TonB-dependent receptor plug domain-containing protein
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
S-adenosyl-L-homocysteine hydrolase NAD binding
Outer membrane protein assembly factor BamE
Urease accessory protein UreH-like transmembrane
Alpha-glycerophosphate oxidase C-terminal
Large ribosomal subunit protein uL15/eL18
ABC-type transport auxiliary lipoprotein component
ABC-type transport auxiliary lipoprotein component domain-containing protein
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Translation elongation factor P/YeiP central
Methylguanine DNA methyltransferase ribonuclease-like
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Flagella basal body P-ring formation protein FlgA
RNA binding; important for wobble base 34 recognition
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Carbamoyl-phosphate synthase small subunit N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Heat-inducible transcription repressor HrcA C-terminal
Tetratricopeptide repeat-like domain-containing protein
Transcription elongation factor GreA/GreB N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Histidine-specific methyltransferase SAM-dependent
Flagellar motor switch protein FliN-like C-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Polysaccharide biosynthesis protein C-terminal
Beta-lactamase hydrolase-like protein phosphatase-like
Beta-lactamase hydrolase-like protein phosphatase-like domain-containing protein
Prepilin type IV endopeptidase peptidase
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
DNA-directed DNA polymerase family A palm
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Anthranilate synthase component I N-terminal
Proton acceptor; for glutaminase activity
PilC beta-propeller domain-containing protein
Activator of Hsp90 ATPase homologue 1-like C-terminal
Transglycosylase SLT domain-containing protein
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Acetyl-CoA hydrolase/transferase C-terminal
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Polysaccharide chain length determinant N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Required for zinc-mediated homotetramerization and catalytic activity
ATP synthase F1 complex delta/epsilon subunit N-terminal
Arginine decarboxylase C-terminal helical
Peptidase M1 membrane alanine aminopeptidase
Large ribosomal subunit protein uL6 alpha-beta
Calcineurin-like phosphoesterase domain-containing protein
Capsule synthesis protein CapA domain-containing protein
NADH:ubiquinone oxidoreductase 30kDa subunit
Transposase IS116/IS110/IS902 C-terminal
Membrane fusion protein biotin-lipoyl like
Peptide methionine sulphoxide reductase MsrA
Microcin J25-processing protein McjB C-terminal
Endonuclease/exonuclease/phosphatase domain-containing protein
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
NADP-dependent oxidoreductase domain-containing protein
TRAP C4-dicarboxylate transport system permease DctM subunit
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Type II secretion system protein GspC N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Alanyl-transfer RNA synthetases family profile
Pyruvate dehydrogenase E1 component middle
Bacterial transcription activator effector binding
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Electron transfer via tryptophanyl radical
Prokaryotic glutathione synthetase ATP-binding
Type-F conjugative transfer system secretin TraK
FAD dependent oxidoreductase domain-containing protein
Outer membrane protein assembly factor BamB
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Transposase IS204/IS1001/IS1096/IS1165 DDE
ABC-type uncharacterised transport system
Essential for prephenate dehydratase activity
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Secretin/TonB short N-terminal domain-containing protein
Release factor glutamine methyltransferase N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Ribosomal RNA adenine methylase transferase N-terminal