Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Glutathionylspermidine synthase pre-ATP-grasp-like
General stress protein FMN-binding split barrel
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Phosphocysteine intermediate; for EIIB activity
Molybdopterin cofactor biosynthesis C (MoaC)
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Aminoacyl-transfer RNA synthetases class-II family profile
Alanyl-transfer RNA synthetases family profile
DNA mismatch repair proteins mutS family
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Glycosyltransferase subfamily 4-like N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
RNA 2-O ribose methyltransferase substrate binding
TRAP C4-dicarboxylate transport system permease DctM subunit
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
Thiamine pyrophosphate enzyme TPP-binding
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Menaquinone biosynthesis protein MenD middle
Thiamine pyrophosphate enzyme N-terminal TPP-binding
RNA polymerase sigma factor 70 region 4 type 2
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Transposase IS116/IS110/IS902 C-terminal
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Thiamin pyrophosphokinase thiamin-binding
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
SGNH hydrolase-type esterase domain-containing protein
Carbamoyl-phosphate synthase small subunit N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
DNA primase/polymerase bifunctional N-terminal
Superoxide dismutase copper/zinc binding
ATP synthase F1 complex delta/epsilon subunit N-terminal
Spore germination GerAC-like C-terminal domain-containing protein
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
ABC transporter substrate-binding protein PnrA-like
Sodium symporter small subunit predicted
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Type I restriction modification DNA specificity
Transposase IS204/IS1001/IS1096/IS1165 DDE
Transposase IS204/IS1001/IS1096/IS1165 helix-turn-helix
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Polysaccharide biosynthesis protein C-terminal
Penicillin-binding protein transpeptidase
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Alpha-D-phosphohexomutase alpha/beta/alpha
Major facilitator superfamily (MFS) profile
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Polysaccharide biosynthesis protein CapD-like
Glycoside hydrolase family 31 N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Type VII secretion system protein EssD-like
Tryptophan RNA-binding attenuator protein
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Schiff-base intermediate with substrate; via pyruvic acid
Helix-hairpin-helix DNA-binding motif class 1
Sodium/calcium exchanger membrane region
Glycosyl transferase family 3 N-terminal
Glycosyl hydrolase family 13 catalytic domain-containing protein
Mannose-6-phosphate isomerase type II C-terminal
Intracellular proteinase inhibitor BsuPI
Bifunctional metallophosphatase/5'-nucleotidase
Chromosomal replication initiator DnaA C-terminal
Flagellar hook-length control protein-like C-terminal
Schiff-base intermediate with dihydroxyacetone-P
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
O-(5'-phospho-DNA)-tyrosine intermediate
Lysidine-tRNA(Ile) synthetase C-terminal
Transcriptional regulator SgrR N-terminal HTH
Cysteine sulfenic acid (-SOH) intermediate
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Sporulation transcription regulator WhiA N-terminal
Urease accessory protein UreH-like transmembrane
Na+-translocating membrane potential-generating system MpsC
6-phosphogluconate dehydrogenase C-terminal
Tryptophan synthase beta chain-like PALP
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
HTH-type transcriptional regulator MT1864/Rv1816-like C-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Large ribosomal subunit protein uL6 alpha-beta
Inner membrane protein YgaP-like transmembrane
Could play a key role in the communication between the regulatory and the substrate sites
Prepilin type IV endopeptidase peptidase
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
SUF system FeS cluster assembly SufBD N-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Gram-positive cocci surface proteins LPxTG domain-containing protein
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Cation-transporting P-type ATPase N-terminal
Resolvase/invertase-type recombinase catalytic
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Important for interaction with partner proteins
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Pyridoxamine 5'-phosphate oxidase putative
Glycine cleavage T-protein C-terminal barrel
O-(3'-phospho-DNA)-tyrosine intermediate
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Positions MEP for the nucleophilic attack
Bacterial type II secretion system protein E
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Phosphomannose isomerase type I catalytic
Polymerase/histidinol phosphatase N-terminal
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase N-terminal
Important for beta-aspartyl-AMP intermediate formation
Na+/H+ antiporter MnhB subunit-related protein
Anthranilate synthase component I N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Sporulation stage II protein D amidase enhancer LytB N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
NIF system FeS cluster assembly NifU N-terminal
Prokaryotic-type class I peptide chain release factors
Phosphatidylglycerol lysyltransferase C-terminal
Cell envelope-related transcriptional attenuator
Sporulation stage IV protein A C-terminal
DNA polymerase III delta subunit C-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Heat-inducible transcription repressor HrcA C-terminal
Cytochrome b/b6 N-terminal region profile
tRNA pseudouridylate synthase B C-terminal
Lantibiotic biosynthesis protein dehydration
Peptidase S9 prolyl oligopeptidase catalytic
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
CobB/CobQ-like glutamine amidotransferase
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Bacterial transcription activator effector binding
Phosphotransferase system enzyme I N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Alpha-glycerophosphate oxidase C-terminal
May play a role in transmitting local conformational changes
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Phosphatidic acid phosphatase type 2/haloperoxidase
Dipicolinate synthase subunit A N-terminal
Threonine/serine exporter-like N-terminal
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Ribosomal RNA adenine methylase transferase N-terminal
Schiff-base intermediate with acetaldehyde
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Septum formation inhibitor MinC C-terminal
Heme-copper oxidase subunit III family profile
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Interaction with polymerase core subunit RpoC
YhcN/YlaJ family sporulation lipoprotein
Pseudouridine synthase I TruA alpha/beta
ABC-type glycine betaine transport system substrate-binding
Large ribosomal subunit protein uL15/eL18
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Glycosyl hydrolase family 30 beta sandwich
Phosphoribosylformylglycinamidine synthase linker
Involved in allosteric activation by GTP
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Peptidase M14 carboxypeptidase A domain-containing protein
Electron transfer via tryptophanyl radical
Increases nucleophilicity of active site Cys
Sporulation initiation phosphotransferase B C-terminal
MucB/RseB N-terminal domain-containing protein
Aconitase A/isopropylmalate dehydratase small subunit swivel
Cytochrome C biogenesis protein transmembrane
Flagellar motor switch protein FliN-like C-terminal
Polysaccharide chain length determinant N-terminal
Solute-binding protein family 3/N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
ABC transporter substrate-binding protein
Major facilitator superfamily associated
Glucosamine/galactosamine-6-phosphate isomerase
Gram-positive cocci surface proteins LPxTG
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Thymidylate synthase/dCMP hydroxymethylase
Plays an important role in substrate specificity
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
DNA-directed DNA polymerase family A palm
Large ribosomal subunit protein uL2 C-terminal
Schiff-base intermediate with D-ribose 5-phosphate
RND efflux pump membrane fusion protein barrel-sandwich
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
RNA binding; important for wobble base 34 recognition
Transcriptional coactivator p15 (PC4) C-terminal
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Nitrite/Sulfite reductase ferredoxin-like
Type III secretion system flagellar brake protein YcgR PilZN
Protein-PII uridylyltransferase N-terminal
Release factor glutamine methyltransferase N-terminal
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Gly-cisPro motif, important for rejection of L-amino acids
SsuA/THI5-like domain-containing protein
Putative aromatic acid exporter C-terminal
Exonuclease VII large subunit C-terminal
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-103)
Reversibly protonated during proton transport
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Cytochrome b/b6 C-terminal region profile
DNA replication/recombination mediator RecO N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Glycosyl hydrolase family 98 putative carbohydrate-binding module
Glycosyl hydrolase family 98 putative carbohydrate-binding module domain-containing protein
Translation elongation factor P/YeiP central
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Ionotropic glutamate receptor C-terminal
Diacylglycerol glucosyltransferase N-terminal
Magnesium transporter MgtE intracellular
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Small ribosomal subunit protein uS4 N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Terminase large subunit gp17-like C-terminal
Sortilin N-terminal domain-containing protein
Pyruvate phosphate dikinase AMP/ATP-binding
Lysozyme inhibitor LprI N-terminal domain-containing protein
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
RDXXRA motif of the pArg binding pocket involved in allosteric regulation
Single-stranded-DNA-specific exonuclease RecJ C-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Cell wall-active antibiotics response LiaF-like C-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Non-canonical purine NTP phosphatase/PRRC1