NADH:flavin oxidoreductase/NADH oxidase N-terminal
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Bacterial type II secretion system protein E
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Transcription factor NikR nickel binding C-terminal
TRAP transporter substrate-binding protein
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Divergent polysaccharide deacetylase family protein
Glycosyltransferase subfamily 4-like N-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
DNA-directed DNA polymerase family A palm
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
HupH hydrogenase expression protein C-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
NADH:ubiquinone oxidoreductase-like 20kDa subunit
FAD-dependent oxidoreductase 2 FAD binding
DNA ligase OB-like domain-containing protein
Aromatic hydrocarbon degradation protein
Pyruvate phosphate dikinase AMP/ATP-binding
RND efflux pump membrane fusion protein barrel-sandwich
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
ATPsynthase alpha/beta subunit N-terminal extension
Sodium/calcium exchanger membrane region
Cytochrome b561 bacterial/Ni-hydrogenase
Major facilitator superfamily (MFS) profile
Cytochrome c-552/4 domain-containing protein
Gamma-butyrobetaine hydroxylase-like N-terminal
Large ribosomal subunit protein uL2 C-terminal
Pyruvate dehydrogenase E1 component middle
Aconitase A/isopropylmalate dehydratase small subunit swivel
Cation-transporting P-type ATPase N-terminal
PHA accumulation regulator DNA-binding N-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Tryptophan synthase beta chain-like PALP
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Fibronectin type III domain-containing protein
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Methylene-tetrahydromethanopterin dehydrogenase N-terminal
Prokaryotic-type class I peptide chain release factors
Molybdate ABC transporter substrate-binding protein
Could be important to modulate the pK values of the two catalytic cysteine residues
Interaction with polymerase core subunit RpoC
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Transglycosylase SLT domain-containing protein
TRAP C4-dicarboxylate transport system permease DctM subunit
Flagellar motor switch protein FliN-like C-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
YbaK/aminoacyl-tRNA synthetase-associated
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Saccharopine dehydrogenase-like C-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Ribosomal RNA small subunit methyltransferase E methyltransferase
Chromosomal replication initiator DnaA C-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
YbgF trimerisation domain-containing protein
Important for substrate binding and specificity
RNA binding; important for wobble base 34 recognition
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Flagellar hook-length control protein-like C-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
ABC-type uncharacterised transport system
Glycosyl transferase family 3 N-terminal
Type III secretion system flagellar brake protein YcgR PilZN
Helix-hairpin-helix DNA-binding motif class 1
Outer membrane protein assembly factor BamA
Urease accessory protein UreH-like transmembrane
Carbamoyl-phosphate synthase small subunit N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Ion-translocating oxidoreductase complex subunit G
Thiol:disulfide interchange protein DsbD
Aminoacyl-transfer RNA synthetases class-II family profile
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Molybdopterin cofactor biosynthesis C (MoaC)
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Chalcone isomerase domain-containing protein
Arsenosugar biosynthesis radical SAM protein ArsS-like C-terminal
Heme-copper oxidase subunit III family profile
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
TonB-dependent receptor-like beta-barrel
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
Siroheme decarboxylase AsnC-like ligand binding
Translation elongation factor P/YeiP central
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
ATP synthase F1 complex delta/epsilon subunit N-terminal
Ribonucleotide reductase large subunit C-terminal
Glutamate synthase alpha subunit C-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Flavocytochrome c sulphide dehydrogenase flavin-binding
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Prepilin type IV endopeptidase peptidase
Menaquinone biosynthesis protein MenD middle
Blue (type 1) copper domain-containing protein
Glycine zipper 2TM domain-containing protein
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Glycine cleavage T-protein C-terminal barrel
O-(5'-phospho-DNA)-tyrosine intermediate
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr C-terminal
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr N-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Peptide methionine sulphoxide reductase MsrA
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Mechanosensitive ion channel inner membrane
Polymerase/histidinol phosphatase N-terminal
Isocitrate dehydrogenase kinase/phosphatase (AceK) kinase
Isocitrate dehydrogenase kinase/phosphatase (AceK) regulatory
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Aldehyde ferredoxin oxidoreductase N-terminal
Rap1a immunity protein domain-containing protein
Cysteine sulfenic acid (-SOH) intermediate
Release factor glutamine methyltransferase N-terminal
Putative Flp pilus-assembly TadG-like N-terminal
Anti-bacteriophage protein A/HamA C-terminal
Important for interaction with partner proteins
Transcription regulator AsnC/Lrp ligand binding
Ribosomal RNA small subunit methyltransferase E PUA-like
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Electron transfer via tryptophanyl radical
Phosphatidic acid phosphatase type 2/haloperoxidase
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-94)
NADH:ubiquinone oxidoreductase 30kDa subunit
Ysc84 actin-binding domain-containing protein
NIF system FeS cluster assembly NifU C-terminal
NIF system FeS cluster assembly NifU N-terminal
Chromosomal replication initiator protein DnaA
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Signal transduction histidine kinase internal region
Alanyl-transfer RNA synthetases family profile
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
RNA polymerase sigma factor 70 region 4 type 2
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Ribosomal RNA adenine methylase transferase N-terminal
Dinitrogenase iron-molybdenum cofactor biosynthesis
Solute-binding protein family 3/N-terminal
Formylmethanofuran dehydrogenase subunit E
Ribose-phosphate pyrophosphokinase N-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Sodium symporter small subunit predicted
Cytochrome C biogenesis protein transmembrane
DNA polymerase III subunit delta C-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Important for beta-aspartyl-AMP intermediate formation
Caspase family p10 domain-containing protein
Anthranilate synthase component I N-terminal
Exonuclease VII large subunit C-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
N-end rule aminoacyl transferase C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Nuclear transport factor 2 family protein
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
S-adenosyl-L-homocysteine hydrolase NAD binding
Putative oxidoreductase/dehydrogenase Rossmann-like
Alpha-D-phosphohexomutase alpha/beta/alpha
Acyl-ester intermediate; for transpeptidase activity
Penicillin-binding protein transpeptidase
Proton donor; for transglycosylase activity
Alpha-glycerophosphate oxidase C-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Large ribosomal subunit protein uL15/eL18
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
CobB/CobQ-like glutamine amidotransferase
Outer membrane lipoprotein-sorting protein
RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein
Cytochrome c-552/DMSO reductase-like haem-binding
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Histidine-specific methyltransferase SAM-dependent
Shikimate dehydrogenase substrate binding N-terminal
Nitrite/Sulfite reductase ferredoxin-like
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Essential for prephenate dehydratase activity
Plays an important role in substrate specificity
DNA mismatch repair proteins mutS family
P-type conjugative transfer protein TrbG
Polysaccharide biosynthesis protein CapD-like
Interacts with tRNA; defines subfamily-specific binding signature
Important for substrate specificity; cannot use PPi as phosphoryl donor
Solute-binding protein family 3/N-terminal domain-containing protein
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Small ribosomal subunit protein uS4 N-terminal
Sugar fermentation stimulation protein C-terminal
NAD(P) transhydrogenase alpha subunit C-terminal
Large ribosomal subunit protein uL6 alpha-beta
Dinitrogenase iron-molybdenum cofactor N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Inner membrane protein YgaP-like transmembrane
Urea ABC transporter permease subunit UrtB
UDP N-acetylglucosamine O-acyltransferase C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Outer membrane protein assembly factor BamE
NADH-ubiquinone oxidoreductase 51kDa subunit FMN-binding
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
Putative regulatory protein FmdB Zinc ribbon
Survival protein SurE-like phosphatase/nucleotidase
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Zinc ABC transporter substrate-binding protein
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Quercetin 2,3-dioxygenase C-terminal cupin
Phosphotransferase system enzyme I N-terminal
Fe/B12 periplasmic-binding domain-containing protein
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Regulator of nucleoside diphosphate kinase N-terminal
Arginine decarboxylase C-terminal helical
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
RNA 2-O ribose methyltransferase substrate binding
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Aminoacyl-tRNA synthetase class I anticodon-binding
Nitrogenase molybdenum-iron protein beta chain N-terminal
S-adenosylmethionine-dependent methyltransferase
Outer membrane protein beta-barrel domain-containing protein
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Endolytic peptidoglycan transglycosylase RlpA
Cytochrome oxidase subunit II copper A binding
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Antitoxin Xre/MbcA/ParS-like toxin-binding
Polypeptide-transport-associated ShlB-type
Polypeptide-transport-associated ShlB-type domain-containing protein
YbhB/YbcL family Raf kinase inhibitor-like protein
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
5-glutamyl coenzyme A thioester intermediate
Increases nucleophilicity of active site Cys