Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Ribonucleotide reductase large subunit C-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Major facilitator superfamily (MFS) profile
Saccharopine dehydrogenase-like C-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Outer membrane protein assembly factor BamD
Polysaccharide biosynthesis protein CapD-like
Translation elongation factor P/YeiP central
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Phosphatidic acid phosphatase type 2/haloperoxidase
Ribose-phosphate pyrophosphokinase N-terminal
Tryptophan synthase beta chain-like PALP
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Bacterial type II secretion system protein E
ATP synthase F1 complex delta/epsilon subunit N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
ABC-type transport auxiliary lipoprotein component domain-containing protein
Large ribosomal subunit protein uL15/eL18
O-(5'-phospho-DNA)-tyrosine intermediate
Microcin J25-processing protein McjB C-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
DNA mismatch repair proteins mutS family
Positions MEP for the nucleophilic attack
Aconitase A/isopropylmalate dehydratase small subunit swivel
Cell division protein FtsQ/DivIB C-terminal
Calcineurin-like phosphoesterase family protein
Small ribosomal subunit protein uS4 N-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-102)
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Glycoside hydrolase family 31 N-terminal
Choloylglycine hydrolase/NAAA C-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Prokaryotic-type class I peptide chain release factors
NADH:ubiquinone oxidoreductase 30kDa subunit
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Important for autoinhibition of adenylyltransferase activity
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Thymidylate synthase/dCMP hydroxymethylase
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Membrane fusion protein biotin-lipoyl like
SUF system FeS cluster assembly SufBD N-terminal
Schiff-base intermediate with substrate; via pyruvic acid
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Peptide methionine sulphoxide reductase MsrA
Important for interaction with partner proteins
Alpha-glycerophosphate oxidase C-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
DNA-directed RNA polymerase RpoA/D/Rpb3-type
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
Resolvase/invertase-type recombinase catalytic
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Pyruvate dehydrogenase E1 component middle
Involved in allosteric activation by GTP
Neurotransmitter-gated ion-channel ligand-binding
Polymerase/histidinol phosphatase N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Nicotinamide phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Superoxide dismutase copper/zinc binding
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Polysaccharide biosynthesis protein C-terminal
Pseudouridine synthase I TruA alpha/beta
Plays an important role in substrate specificity
Gly-cisPro motif, important for rejection of L-amino acids
Heme-copper oxidase subunit III family profile
Required for zinc-mediated homotetramerization and catalytic activity
Lysidine-tRNA(Ile) synthetase C-terminal
Lactonase, 7-bladed beta-propeller family protein
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Signal recognition particle SRP54 helical bundle
Alpha-D-phosphohexomutase alpha/beta/alpha
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Electron transfer via tryptophanyl radical
Proline utilization A proline dehydrogenase N-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Penicillin-binding protein transpeptidase
DNA replication/recombination mediator RecO N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Interaction with polymerase core subunit RpoC
RND efflux pump membrane fusion protein barrel-sandwich
Large ribosomal subunit protein uL2 C-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Phosphoadenosine phosphosulphate reductase
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Glycine cleavage T-protein C-terminal barrel
RNA 2-O ribose methyltransferase substrate binding
Glycosyl transferase family 3 N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
2-isopropylmalate synthase LeuA allosteric (dimerisation)
Cysteine sulfenic acid (-SOH) intermediate
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
DNA polymerase III delta subunit C-terminal
Prepilin type IV endopeptidase peptidase
DNA-directed DNA polymerase family A palm
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Large ribosomal subunit protein bL25 L25
UDP N-acetylglucosamine O-acyltransferase C-terminal
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Acyl-CoA dehydrogenase C-terminal bacterial-type
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Outer membrane beta-barrel domain protein
Chromosomal replication initiator DnaA C-terminal
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Helix-hairpin-helix DNA-binding motif class 1
Alanyl-transfer RNA synthetases family profile
Release factor glutamine methyltransferase N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Organic solvent tolerance-like N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
tRNA pseudouridylate synthase B C-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Membrane-bound lytic murein transglycosylase A
Sec translocon accessory complex subunit YajC
Large ribosomal subunit protein uL30-like ferredoxin-like fold
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Outer membrane protein assembly factor BamE
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Glycerol-3-phosphate dehydrogenase [NAD(P)+]
Could play a key role in the communication between the regulatory and the substrate sites
Tetrahydrodipicolinate-N-succinyltransferase chain A
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Anthranilate synthase component I N-terminal
Reversibly protonated during proton transport
Peptidyl-prolyl cis-trans isomerase FKBP-type N-terminal
Protein O-mannosyl-transferase C-terminal four TM
Large ribosomal subunit protein uL6 alpha-beta
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Ribosomal RNA adenine methylase transferase N-terminal
Outer-membrane lipoprotein carrier protein