Sortilin N-terminal domain-containing protein
TRAP C4-dicarboxylate transport system permease DctM subunit
Major facilitator superfamily (MFS) profile
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Alpha-glycerophosphate oxidase C-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Resolvase/invertase-type recombinase catalytic
RDXXRA motif of the pArg binding pocket involved in allosteric regulation
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Aminoacyl-transfer RNA synthetases class-II family profile
RNA 2-O ribose methyltransferase substrate binding
Thiamine pyrophosphate enzyme TPP-binding
RNA polymerase sigma factor 70 region 4 type 2
Peptidase S9 prolyl oligopeptidase catalytic
Cytochrome c-type biogenesis protein CcmF C-terminal
Transcription elongation factor GreA/GreB C-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Acyl-CoA dehydrogenase/oxidase C-terminal
1,4-alpha-glucan branching enzyme C-terminal
Glycoside hydrolase family 57 N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Polysaccharide biosynthesis protein CapD-like
Schiff-base intermediate with acetaldehyde
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Transposase IS116/IS110/IS902 C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Electron transfer flavoprotein alpha/beta-subunit N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Flagellar Assembly Protein A N-terminal region
Solute-binding protein family 3/N-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
O-(3'-phospho-DNA)-tyrosine intermediate
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Transposon Tn7 transposition protein TnsD C-terminal
Copper amine oxidase-like N-terminal domain-containing protein
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Aldehyde ferredoxin oxidoreductase N-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
ABC transporter substrate-binding protein PnrA-like
tRNA pseudouridylate synthase B C-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Moybdenum cofactor oxidoreductase dimerisation
Could play a key role in the communication between the regulatory and the substrate sites
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Cell wall-active antibiotics response LiaF-like C-terminal
Phosphoadenosine phosphosulphate reductase
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
N6 adenine-specific DNA methyltransferase N-terminal
DNA replication/recombination mediator RecO N-terminal
Intracellular proteinase inhibitor BsuPI
Intracellular proteinase inhibitor BsuPI domain-containing protein
Transcription elongation factor GreA/GreB N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Heme-copper oxidase subunit III family profile
Alanyl-transfer RNA synthetases family profile
Sporulation transcription regulator WhiA N-terminal
Tryptophan synthase beta chain-like PALP
Divergent polysaccharide deacetylase family protein
Large ribosomal subunit protein uL6 alpha-beta
Phosphatidic acid phosphatase type 2/haloperoxidase
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Cell envelope-related transcriptional attenuator
Dihydrodipicolinate reductase N-terminal
Meso-diaminopimelate D-dehydrogenase C-terminal
Phosphocysteine intermediate; for EIIB activity
Transposase IS204/IS1001/IS1096/IS1165 DDE
Transposase IS204/IS1001/IS1096/IS1165 helix-turn-helix
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
Alpha-D-phosphohexomutase alpha/beta/alpha
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
6-phosphogluconate dehydrogenase C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Bacterial type II secretion system protein E
Biopterin-dependent aromatic amino acid hydroxylase family profile
CobB/CobQ-like glutamine amidotransferase
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Phosphotransferase system enzyme I N-terminal
Ribonucleotide reductase large subunit C-terminal
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Sporulation stage II protein D amidase enhancer LytB N-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Pseudouridine synthase I TruA alpha/beta
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Single-stranded-DNA-specific exonuclease RecJ C-terminal
NIF system FeS cluster assembly NifU C-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
SUF system FeS cluster assembly SufBD N-terminal
RNA binding; important for wobble base 34 recognition
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Exonuclease VII large subunit C-terminal
Schiff-base intermediate with D-ribose 5-phosphate
Aconitase A/isopropylmalate dehydratase small subunit swivel
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Penicillin-binding protein transpeptidase
Aspartate/homoserine dehydrogenase NAD-binding
Peptidoglycan recognition protein family
Nucleophile; cysteine thiosulfonate intermediate
Cytochrome b561 bacterial/Ni-hydrogenase
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Proteinase inhibitor I42 chagasin domain-containing protein
Pyruvate/ketoisovalerate oxidoreductase catalytic
Plays an important role in substrate specificity
DnaJ homologue subfamily C member 28 conserved
Quercetin 2,3-dioxygenase C-terminal cupin
Pyrimidine nucleoside phosphorylase C-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Cation-transporting P-type ATPase N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Interaction with polymerase core subunit RpoC
Important for beta-aspartyl-AMP intermediate formation
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Cytochrome C biogenesis protein transmembrane
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Na+/H+ antiporter MnhB subunit-related protein
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Polysaccharide chain length determinant N-terminal
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Ionotropic glutamate receptor C-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Sodium/calcium exchanger membrane region
Involved in allosteric activation by GTP
Helix-hairpin-helix DNA-binding motif class 1
Type I restriction modification DNA specificity
Pyridoxamine 5'-phosphate oxidase putative
Nitrite/Sulfite reductase ferredoxin-like
Putative aromatic acid exporter C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase N-terminal
Diacylglycerol glucosyltransferase N-terminal
Glycosyl transferase family 28 C-terminal
ABC-type glycine betaine transport system substrate-binding
Large ribosomal subunit protein uL15/eL18
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Polymerase/histidinol phosphatase N-terminal
Ger(X)C family spore germination protein
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
NADH:ubiquinone/plastoquinone oxidoreductase chloroplast chain 5 C-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Important for interaction with partner proteins
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Sodium symporter small subunit predicted
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Prepilin type IV endopeptidase peptidase
Positions MEP for the nucleophilic attack
Translation elongation factor P/YeiP central
Lactate utilization protein B C-terminal
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Polysaccharide biosynthesis protein C-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Fe/B12 periplasmic-binding domain-containing protein
Chromosomal replication initiator DnaA C-terminal
Gram-positive cocci surface proteins LPxTG domain-containing protein
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Anthranilate synthase component I N-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Mandelate racemase/muconate lactonizing enzyme C-terminal
Saccharopine dehydrogenase-like C-terminal
Tryptophan RNA-binding attenuator protein
Thymidylate synthase/dCMP hydroxymethylase
Shikimate dehydrogenase substrate binding N-terminal
Sporulation initiation phosphotransferase B C-terminal
Small ribosomal subunit protein uS4 N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Terminase large subunit-like endonuclease
Flagellar motor switch protein FliN-like C-terminal
Large ribosomal subunit protein uL2 C-terminal
Cytochrome b/b6 N-terminal region profile
Septum formation inhibitor MinC C-terminal
Transcriptional coactivator p15 (PC4) C-terminal
Thiamin pyrophosphokinase thiamin-binding
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Influences the redox potential of the prosthetic heme and FAD groups
Involved in heme-bound ligand stabilization and O-O bond activation
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Type III secretion system flagellar brake protein YcgR PilZN
Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Cysteine sulfenic acid (-SOH) intermediate
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Aromatic amino acid beta-eliminating lyase/threonine aldolase
General stress protein FMN-binding split barrel
Glycosyl transferase family 3 N-terminal
ABC transporter periplasmic binding protein yphF
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Cytochrome b/b6 C-terminal region profile
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-101)
Sigma 54 modulation/S30EA ribosomal protein C-terminal
NIF system FeS cluster assembly NifU N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Tellurite resistance methyltransferase TehB-like
6-hydroxymethylpterin diphosphokinase MptE-like
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Signal transduction histidine kinase 5TM receptor LytS transmembrane region
Signal transduction histidine kinase internal region
Glycine cleavage T-protein C-terminal barrel
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Pyruvate phosphate dikinase AMP/ATP-binding
Membrane insertase YidC/Oxa/ALB C-terminal
Sporulation stage IV protein A C-terminal
DNA mismatch repair proteins mutS family
Molybdopterin cofactor biosynthesis C (MoaC)
Methylguanine DNA methyltransferase ribonuclease-like
O-(5'-phospho-DNA)-tyrosine intermediate
NADH:ubiquinone oxidoreductase 30kDa subunit
Glycosyltransferase family 28 N-terminal
Non-canonical purine NTP phosphatase/PRRC1
Gly-cisPro motif, important for rejection of L-amino acids