Prokaryotic-type class I peptide chain release factors
RNA 2-O ribose methyltransferase substrate binding
Phosphotransferase system enzyme I N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
RNA polymerase sigma factor 70 region 4 type 2
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Cysteine sulfenic acid (-SOH) intermediate
Tryptophan synthase beta chain-like PALP
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Large ribosomal subunit protein uL15/eL18
Threonine/serine exporter-like N-terminal
Major facilitator superfamily (MFS) profile
Heat-inducible transcription repressor HrcA C-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Positions MEP for the nucleophilic attack
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
Small ribosomal subunit protein uS4 N-terminal
Beta-hexosaminidase bacterial type N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Exonuclease VII large subunit C-terminal
AB hydrolase-1 domain-containing protein
Large ribosomal subunit protein uL2 C-terminal
PhoD-like phosphatase metallophosphatase
Aminoacyl-transfer RNA synthetases class-II family profile
Involved in ionization of N3 of dUMP, leading to its activation
Interaction with polymerase core subunit RpoC
Translation elongation factor P/YeiP central
Peptidase S9 prolyl oligopeptidase catalytic
DNA-directed RNA polymerase RpoA/D/Rpb3-type
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Schiff-base intermediate with substrate; via pyruvic acid
Ribosome maturation factor RimP N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Shikimate dehydrogenase substrate binding N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Alpha-D-phosphohexomutase alpha/beta/alpha
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Phosphomannose isomerase type I catalytic
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Pyruvate/ketoisovalerate oxidoreductase catalytic
Glycosyltransferase subfamily 4-like N-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Polymerase/histidinol phosphatase N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Alanyl-transfer RNA synthetases family profile
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Cell envelope-related transcriptional attenuator
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Essential for prephenate dehydratase activity
Glycosyl transferase family 3 N-terminal
Large ribosomal subunit protein uL6 alpha-beta
O-(3'-phospho-DNA)-tyrosine intermediate
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Reversibly protonated during proton transport
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Sporulation transcription regulator WhiA N-terminal
Helix-hairpin-helix DNA-binding motif class 1
S-adenosyl-L-homocysteine hydrolase NAD binding
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Peptidase M1 membrane alanine aminopeptidase
Transglycosylase SLT domain-containing protein
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Plays an important role in substrate specificity
Endoribonuclease L-PSP/chorismate mutase-like
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Alpha galactosidase C-terminal beta sandwich
DNA-directed DNA polymerase family A palm
Thiamine pyrophosphate enzyme TPP-binding
Important for substrate specificity; cannot use PPi as phosphoryl donor
Aconitase A/isopropylmalate dehydratase small subunit swivel
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
SUF system FeS cluster assembly SufBD N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Calcineurin-like phosphoesterase domain-containing protein
NIF system FeS cluster assembly NifU N-terminal
NIF system FeS cluster assembly NifU C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Could be important to modulate the pK values of the two catalytic cysteine residues
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
ATP synthase F1 complex delta/epsilon subunit N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Could play a key role in the communication between the regulatory and the substrate sites
tRNA(Ile)-lysidine synthase substrate-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Nicotinate phosphoribosyltransferase N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Schiff-base intermediate with D-ribose 5-phosphate
Thiamine pyrophosphate enzyme N-terminal TPP-binding
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
NAD(P) transhydrogenase alpha subunit C-terminal