Exonuclease VII large subunit C-terminal
Polymerase/histidinol phosphatase N-terminal
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Glycosyltransferase subfamily 4-like N-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Cell envelope-related transcriptional attenuator
Involved in allosteric activation by GTP
ABC transporter substrate-binding protein PnrA-like
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Polysaccharide chain length determinant N-terminal
Translation elongation factor P/YeiP central
Large ribosomal subunit protein uL6 alpha-beta
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Carbamoyl-phosphate synthase small subunit N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Aminoacyl-transfer RNA synthetases class-II family profile
Flagellar motor switch protein FliN-like C-terminal
Important for substrate specificity; cannot use PPi as phosphoryl donor
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Reversibly protonated during proton transport
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Positions MEP for the nucleophilic attack
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Shikimate dehydrogenase substrate binding N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Thiamin pyrophosphokinase thiamin-binding
Threonine/serine exporter-like N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Pyruvate phosphate dikinase AMP/ATP-binding
Penicillin-binding protein transpeptidase
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Meso-diaminopimelate D-dehydrogenase C-terminal
Thymidylate synthase/dCMP hydroxymethylase
Polysaccharide biosynthesis protein C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Ig protease IdeS domain-containing protein
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Tryptophan synthase beta chain-like PALP
Alanyl-transfer RNA synthetases family profile
Major facilitator superfamily (MFS) profile
Phosphocysteine intermediate; for EIIB activity
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Diacylglycerol glucosyltransferase N-terminal
Glycosyl transferase family 28 C-terminal
Interaction with polymerase core subunit RpoC
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Small ribosomal subunit protein uS4 N-terminal
Gamma-glutamylcyclotransferase AIG2-like
Phosphatidic acid phosphatase type 2/haloperoxidase
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Prokaryotic-type class I peptide chain release factors
Bacterial type II secretion system protein E
Gly-cisPro motif, important for rejection of L-amino acids
Polysaccharide biosynthesis protein CapD-like
Phosphotransferase system enzyme I N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Schiff-base intermediate with acetaldehyde
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Cation-transporting P-type ATPase N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
DNA-directed RNA polymerase RpoA/D/Rpb3-type
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Pyrimidine nucleoside phosphorylase C-terminal
RNA binding; important for wobble base 34 recognition
Dinitrogenase iron-molybdenum cofactor biosynthesis
D-galactose/methyl-galactoside binding periplasmic protein MglB
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
N-acetylneuraminic acid synthase N-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Sporulation stage IV protein A C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Helix-hairpin-helix DNA-binding motif class 1
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
YbaK/aminoacyl-tRNA synthetase-associated
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Glycosyl hydrolase family 98 putative carbohydrate-binding module
Alpha-D-phosphohexomutase alpha/beta/alpha
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Transposase IS116/IS110/IS902 C-terminal
DNA polymerase III delta subunit C-terminal
Resolvase/invertase-type recombinase catalytic
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
tRNA pseudouridylate synthase B C-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
AMP-activated protein kinase glycogen-binding
Ribose-phosphate pyrophosphokinase N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Glycosyltransferase family 28 N-terminal
Proton acceptor; for glutaminase activity
Prepilin type IV endopeptidase peptidase
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
ATPsynthase alpha/beta subunit N-terminal extension
Peptidoglycan recognition protein family
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Flagellar Assembly Protein A N-terminal region
Large ribosomal subunit protein bL9 C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Glucosamine/galactosamine-6-phosphate isomerase
Schiff-base intermediate with substrate; via pyruvic acid
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Flagellar hook-length control protein-like C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
RNA 2-O ribose methyltransferase substrate binding
Large ribosomal subunit protein uL15/eL18
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Type I restriction modification DNA specificity
NADH-rubredoxin oxidoreductase C-terminal
Gram-positive cocci surface proteins LPxTG
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
CobB/CobQ-like glutamine amidotransferase
DNA mismatch repair proteins mutS family
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Sodium/calcium exchanger membrane region
Anthranilate synthase component I N-terminal
Inosine/uridine-preferring nucleoside hydrolase
FAD-dependent oxidoreductase 2 FAD binding
Nitrite/Sulfite reductase ferredoxin-like
Release factor glutamine methyltransferase N-terminal
Sporulation stage II protein D amidase enhancer LytB N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Phosphomannose isomerase type I catalytic
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
O-(5'-phospho-DNA)-tyrosine intermediate
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
DNA-directed DNA polymerase family A palm
Increases nucleophilicity of active site Cys
serine-type D-Ala-D-Ala carboxypeptidase
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
Sugar fermentation stimulation protein C-terminal
DNA replication/recombination mediator RecO N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase