Saccharopine dehydrogenase-like C-terminal
Signal transduction histidine kinase internal region
RNA polymerase sigma factor 70 region 4 type 2
TonB-dependent receptor-like beta-barrel
Aminoacyl-transfer RNA synthetases class-II family profile
Transition state stabilizer; via amide nitrogen
Penicillin-binding protein transpeptidase
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
3-keto-disaccharide hydrolase domain-containing protein
S-adenosylmethionine-dependent methyltransferase
Quercetin 2,3-dioxygenase C-terminal cupin
Gamma-glutamylcyclotransferase AIG2-like
Sialate O-acetylesterase domain-containing protein
Secretion system C-terminal sorting domain-containing protein
D-glucuronyl C5-epimerase C-terminal domain-containing protein
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
SUF system FeS cluster assembly SufBD N-terminal
Outer membrane protein beta-barrel domain-containing protein
Peptidase C14 caspase domain-containing protein
Bacterial DNA polymerase III alpha subunit NTPase
DNA polymerase helix-hairpin-helix motif
Major facilitator superfamily (MFS) profile
Transposase IS116/IS110/IS902 C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
PBCV-specific basic adaptor domain-containing protein
ATP-grasp fold succinyl-CoA synthetase-type
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Alpha glucuronidase N-terminal domain-containing protein
Activator of Hsp90 ATPase homologue 1-like C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Glycosyltransferase subfamily 4-like N-terminal
Heme-copper oxidase subunit III family profile
Chromosomal replication initiator DnaA C-terminal
Choloylglycine hydrolase/NAAA C-terminal
Choloylglycine hydrolase/NAAA C-terminal domain-containing protein
Amidohydrolase-related domain-containing protein
Tail specific protease domain-containing protein
Thiol:disulfide interchange protein DsbD N-terminal
Thiol:disulfide interchange protein DsbD N-terminal domain-containing protein
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Signal transduction histidine kinase internal region domain-containing protein
Putative auto-transporter adhesin head GIN
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Aromatic amino acid beta-eliminating lyase/threonine aldolase domain-containing protein
Polysaccharide biosynthesis protein C-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Phosphatidylglycerol lysyltransferase C-terminal
Beta-lactamase-related domain-containing protein
Type IX secretion system membrane protein PorP/SprF
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Peptidase M1 membrane alanine aminopeptidase
Beta-lactamase-inhibitor-like PepSY-like domain-containing protein
Fibronectin type-III domain-containing protein
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
DNA replication/recombination mediator RecO N-terminal
SusD/RagB family nutrient-binding outer membrane lipoprotein
Cationic amino acid transporter C-terminal
Proton acceptor; for glutaminase activity
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Tryptophan synthase beta chain-like PALP
SusE outer membrane protein domain-containing protein
Ribose-phosphate pyrophosphokinase N-terminal
Glycoside hydrolase family 65 central catalytic
Mannose-6-phosphate isomerase type II C-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Schiff-base intermediate with substrate; via pyruvic acid
Serine aminopeptidase S33 domain-containing protein
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Large ribosomal subunit protein uL2 C-terminal
Positions MEP for the nucleophilic attack
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Histidine kinase domain-containing protein
UDP N-acetylglucosamine O-acyltransferase C-terminal
Polysaccharide biosynthesis protein GumN
Thiamine pyrophosphate enzyme TPP-binding
Bacterial surface antigen (D15) domain-containing protein
Pyrroline-5-carboxylate reductase catalytic N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Survival protein SurE-like phosphatase/nucleotidase
NAD(P) transhydrogenase alpha subunit C-terminal
Type I restriction enzyme R protein N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Phosphatidic acid phosphatase type 2/haloperoxidase
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
6-phosphogluconate dehydrogenase NADP-binding
Prokaryotic-type class I peptide chain release factors
Polysaccharide chain length determinant N-terminal
Cation-transporting P-type ATPase N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Photosynthesis system II assembly factor Ycf48/Hcf136-like
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
O-(5'-phospho-DNA)-tyrosine intermediate
TonB-dependent receptor plug domain-containing protein
Plays an important role in substrate specificity
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Resolvase/invertase-type recombinase catalytic
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Polymerase/histidinol phosphatase N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Pyruvate phosphate dikinase AMP/ATP-binding
RNA 2-O ribose methyltransferase substrate binding
Glyoxalase/fosfomycin resistance/dioxygenase
Pectate lyase superfamily protein domain-containing protein
Lysidine-tRNA(Ile) synthetase C-terminal
Carboxypeptidase regulatory-like domain-containing protein
Glycosyl hydrolase-like 10 domain-containing protein
Calcineurin-like phosphoesterase C-terminal
Calcineurin-like phosphoesterase N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Right handed beta helix domain-containing protein
NigD-like C-terminal beta sandwich domain-containing protein
Reversibly protonated during proton transport
Translation elongation factor P/YeiP central
Could be important to modulate the pK values of the two catalytic cysteine residues
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Endonuclease/exonuclease/phosphatase domain-containing protein
Cytochrome C biogenesis protein transmembrane
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
TonB-dependent receptor-like beta-barrel domain-containing protein
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Peptidase M14 carboxypeptidase A domain-containing protein
Putative auto-transporter adhesin head GIN domain-containing protein
Aminotransferase class I/classII domain-containing protein
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Lipocalin-like domain-containing protein
Bacterial bifunctional deaminase-reductase C-terminal
Gliding motility-associated protein GldM C-terminal
LamG-like jellyroll fold domain-containing protein
Pesticidal crystal protein Cry22Aa Ig-like
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Peptidase S9 prolyl oligopeptidase catalytic
Carboxypeptidase-like regulatory domain-containing protein
TonB C-terminal domain-containing protein
Glycosyl-hydrolase 97 C-terminal oligomerisation
Chitobiase/beta-hexosaminidases N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Phosphoribosylformylglycinamidine synthase linker
Beta-lactamase class A catalytic domain-containing protein
DNA topoisomerase I catalytic core eukaryotic-type
RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein
Trigger factor ribosome-binding bacterial
Release factor glutamine methyltransferase N-terminal
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Two component regulator three Y domain-containing protein
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
DNA mismatch repair proteins mutS family
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Auto-transporter adhesin head GIN domain-containing protein
Beta-hexosaminidase bacterial type N-terminal
Putative glycogen debranching enzyme N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aromatic hydrocarbon degradation membrane protein
Ricin B lectin domain-containing protein
Glycosyl transferase family 3 N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Glutathionylspermidine synthase pre-ATP-grasp-like
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Thymidylate synthase/dCMP hydroxymethylase
Small ribosomal subunit protein uS4 N-terminal
Cyclophilin-like domain-containing protein
Phospholipase C/D domain-containing protein
Haem-binding uptake Tiki superfamily ChaN domain-containing protein
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
tRNA pseudouridylate synthase B C-terminal
Membrane fusion protein biotin-lipoyl like
Periplasmic copper-binding protein NosD beta helix
Peptidase C39-like domain-containing protein
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Shikimate dehydrogenase substrate binding N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
General stress protein FMN-binding split barrel
Aminopeptidase P N-terminal domain-containing protein
Threonine/serine exporter-like N-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
DNA-directed DNA polymerase family A palm
Peptidase S8/S53 domain-containing protein
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Lysozyme inhibitor LprI N-terminal domain-containing protein
6-phosphogluconate dehydrogenase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Glycosyl hydrolase family 30 beta sandwich
Important for beta-aspartyl-AMP intermediate formation
Cation-transporting P-type ATPase C-terminal
Pseudouridine synthase I TruA alpha/beta
Peptidase M16 C-terminal domain-containing protein
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:ubiquinone/plastoquinone oxidoreductase chloroplast chain 5 C-terminal
Soluble ligand binding domain-containing protein
Heavy metal binding domain-containing protein
Glycine cleavage T-protein C-terminal barrel
Butirosin biosynthesis protein H N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-112)
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Beta-hexosaminidase bacterial type N-terminal domain-containing protein
N-sulphoglucosamine sulphohydrolase C-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Gfo/Idh/MocA-like oxidoreductase bacterial type C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Transglutaminase-like domain-containing protein
Inward rectifier potassium channel C-terminal
Autotransporter domain-containing protein
Phosphomannose isomerase type I catalytic
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Peptidoglycan recognition protein family
Acetylserotonin O-methyltransferase dimerisation
ATP synthase F1 complex delta/epsilon subunit N-terminal
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
Phosphodiester glycosidase domain-containing protein
Schiff-base intermediate with acetaldehyde
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Helix-hairpin-helix DNA-binding motif class 1 domain-containing protein
Bacteroidetes PKD-like domain-containing protein
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Bacterial transcription activator effector binding
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Beta-xylosidase C-terminal Concanavalin A-like
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Gliding motility-associated protein GldM N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Tetrahydrodipicolinate-N-succinyltransferase chain A
Peptide methionine sulfoxide reductase MsrB
Pyrroline-5-carboxylate reductase dimerisation
Gly-cisPro motif, important for rejection of L-amino acids
Sodium/calcium exchanger membrane region
Cell division protein FtsQ/DivIB C-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Organic solvent tolerance-like N-terminal
Organic solvent tolerance-like N-terminal domain-containing protein
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Cytochrome c-552/4 domain-containing protein
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Sortilin N-terminal domain-containing protein
Homogentisate 1,2-dioxygenase N-terminal
Large ribosomal subunit protein uL15/eL18
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Metallo-beta-lactamase domain-containing protein
Aspartate/homoserine dehydrogenase NAD-binding
Methylguanine DNA methyltransferase ribonuclease-like
Leucine-binding protein domain-containing protein
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Cysteine sulfenic acid (-SOH) intermediate
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Pectinesterase catalytic domain-containing protein
DNA glycosylase/AP lyase H2TH DNA-binding
Formamidopyrimidine-DNA glycosylase catalytic
O-(3'-phospho-DNA)-tyrosine intermediate
Dipeptidylpeptidase IV N-terminal domain-containing protein
Large ribosomal subunit protein uL6 alpha-beta