Transposase IS204/IS1001/IS1096/IS1165 DDE
Transposase IS204/IS1001/IS1096/IS1165 helix-turn-helix
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
Gfo/Idh/MocA-like oxidoreductase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Gfo/Idh/MocA-like oxidoreductase C-terminal
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Lantibiotic biosynthesis protein dehydration
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Probable transposase IS891/IS1136/IS1341
Gly-cisPro motif, important for rejection of L-amino acids
Large ribosomal subunit protein uL15/eL18
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
O-(3'-phospho-DNA)-tyrosine intermediate
NADH:flavin oxidoreductase/NADH oxidase N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
DNA polymerase III delta subunit C-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Reversibly protonated during proton transport
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Tryptophan synthase beta chain-like PALP
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Alpha-glycerophosphate oxidase C-terminal
Cell envelope-related transcriptional attenuator
Superoxide dismutase copper/zinc binding
Resolvase/invertase-type recombinase catalytic
Alpha-D-phosphohexomutase alpha/beta/alpha
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Schiff-base intermediate with acetaldehyde
TRAP C4-dicarboxylate transport system permease DctM subunit
Transposase IS116/IS110/IS902 C-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Cyclic nucleotide-binding domain-containing protein
Peptidase S9 prolyl oligopeptidase catalytic
Sporulation stage IV protein A C-terminal
Major facilitator superfamily (MFS) profile
tRNA pseudouridylate synthase B C-terminal
Helix-hairpin-helix DNA-binding motif class 1
Polymerase/histidinol phosphatase N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
PrcB C-terminal domain-containing protein
RDXXRA motif of the pArg binding pocket involved in allosteric regulation
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Translation elongation factor P/YeiP central
Nitrite/Sulfite reductase ferredoxin-like
C4-dicarboxylate ABC transporter substrate-binding protein
Pyrimidine nucleoside phosphorylase C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Heme-copper oxidase subunit III family profile
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Large ribosomal subunit protein uL6 alpha-beta
NIF system FeS cluster assembly NifU N-terminal
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Transcriptional coactivator p15 (PC4) C-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Meso-diaminopimelate D-dehydrogenase C-terminal
Chromosomal replication initiator DnaA C-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Small peptidoglycan-associated lipoprotein
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Abortive infection protein-like C-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
ABC-type glycine betaine transport system substrate-binding
RNA 2-O ribose methyltransferase substrate binding
DnaJ homologue subfamily C member 28 conserved
Inosine/uridine-preferring nucleoside hydrolase
Membrane insertase YidC/Oxa/ALB C-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
RNA polymerase sigma factor 70 region 4 type 2
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Cytochrome C biogenesis protein transmembrane
Penicillin-binding protein transpeptidase
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Ribose-phosphate pyrophosphokinase N-terminal
5-glutamyl coenzyme A thioester intermediate
Plays an important role in substrate specificity
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Saccharopine dehydrogenase-like C-terminal
Glycosyltransferase subfamily 4-like N-terminal
Non-canonical purine NTP phosphatase/PRRC1
Important for autoinhibition of adenylyltransferase activity
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Defence against restriction A C-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Molybdopterin cofactor biosynthesis C (MoaC)
Schiff-base intermediate with substrate; via pyruvic acid
Phosphatidic acid phosphatase type 2/haloperoxidase
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Sporulation transcription regulator WhiA N-terminal
Important for beta-aspartyl-AMP intermediate formation
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Prokaryotic-type class I peptide chain release factors
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Sodium/calcium exchanger membrane region
SUF system FeS cluster assembly SufBD N-terminal
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Tryptophan RNA-binding attenuator protein
Glucose-methanol-choline oxidoreductase N-terminal
Release factor glutamine methyltransferase N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Activator of Hsp90 ATPase homologue 1-like C-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
SsuA/THI5-like domain-containing protein
Pseudouridine synthase I TruA alpha/beta
Septum formation inhibitor MinC C-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Cytochrome b/b6 C-terminal region profile
Essential for prephenate dehydratase activity
Solute-binding protein family 3/N-terminal
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Alanyl-transfer RNA synthetases family profile
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Thymidylate synthase/dCMP hydroxymethylase
DNA-directed DNA polymerase family A palm
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Exonuclease VII large subunit C-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Hydroxymethylglutaryl-coenzyme A synthase C-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
Small ribosomal subunit protein uS4 N-terminal
Cell wall-active antibiotics response LiaF-like C-terminal
DNA replication/recombination mediator RecO N-terminal
General stress protein FMN-binding split barrel
Thiamin/hydroxymethyl pyrimidine-binding YkoF putative
Menaquinone biosynthesis protein MenD middle
Aconitase A/isopropylmalate dehydratase small subunit swivel
Involved in allosteric activation by GTP
Peptidoglycan binding-like domain-containing protein
Anthranilate synthase component I N-terminal
Influences the redox potential of the prosthetic heme and FAD groups
Involved in heme-bound ligand stabilization and O-O bond activation
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
X-X-X-Leu-X-X-Gly heptad repeat-containing protein
Tellurite resistance methyltransferase TehB-like
Peptide methionine sulphoxide reductase MsrA
Integral membrane protein YccS N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Putative Flp pilus-assembly TadG-like N-terminal
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Large ribosomal subunit protein uL2 C-terminal
Diacylglycerol glucosyltransferase N-terminal
Glycosyl transferase family 28 C-terminal
Putative aromatic acid exporter C-terminal
Bacterial type II secretion system protein E
DNA mismatch repair proteins mutS family
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Schiff-base intermediate with D-ribose 5-phosphate
Important for interaction with partner proteins
Phosphocysteine intermediate; for EIIB activity
Cytochrome b/b6 N-terminal region profile
NIF system FeS cluster assembly NifU C-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
ABC transporter substrate-binding protein PnrA-like
ABC transporter substrate-binding protein PnrA-like domain-containing protein
Phosphotransferase system enzyme I N-terminal
Glycosyltransferase family 28 N-terminal
Cysteine sulfenic acid (-SOH) intermediate
Lysidine-tRNA(Ile) synthetase C-terminal
Prepilin type IV endopeptidase peptidase
RNA binding; important for wobble base 34 recognition
Membrane fusion protein biotin-lipoyl like
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Type I restriction modification DNA specificity
6-phosphogluconate dehydrogenase C-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Phosphomannose isomerase type I catalytic
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Serine aminopeptidase S33 domain-containing protein
Cation-transporting P-type ATPase N-terminal
Glycine cleavage T-protein C-terminal barrel
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Na+/H+ antiporter MnhB subunit-related protein
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Glycosyl transferase family 3 N-terminal
Single-stranded-DNA-specific exonuclease RecJ C-terminal
Involved in proton transfer during cleavage
Interaction with polymerase core subunit RpoC
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Major facilitator superfamily associated
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
ATP synthase F1 complex delta/epsilon subunit N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Polysaccharide biosynthesis protein C-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Terminase large subunit-like endonuclease
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Shikimate dehydrogenase substrate binding N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Threonine/serine exporter-like N-terminal
Schiff-base intermediate with dihydroxyacetone-P