TonB-dependent receptor-like beta-barrel
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Penicillin-binding protein transpeptidase
RND efflux pump membrane fusion protein barrel-sandwich
Major facilitator superfamily (MFS) profile
N6 adenine-specific DNA methyltransferase N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Adaptive response protein AidB N-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Sulfatase-modifying factor enzyme domain-containing protein
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
O-(5'-phospho-DNA)-tyrosine intermediate
RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Acyl-CoA dehydrogenase C-terminal bacterial-type
Pyridoxamine 5'-phosphate oxidase putative
Tryptophan synthase beta chain-like PALP
Bacterial surface antigen (D15) domain-containing protein
Pyruvate phosphate dikinase AMP/ATP-binding
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
S-adenosylmethionine-dependent methyltransferase
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Pyrroline-5-carboxylate reductase catalytic N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Type 4 fimbrial biogenesis protein PilX N-terminal
DNA mismatch repair proteins mutS family
Glucosamine/galactosamine-6-phosphate isomerase
PhoD-like phosphatase metallophosphatase
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Outer membrane protein assembly factor BamD
Cytochrome c-type biogenesis protein CcmF C-terminal
Flagellar hook-length control protein-like C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Anthranilate synthase component I N-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Electron transfer via tryptophanyl radical
Transcriptional regulator AbiEi antitoxin N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Mechanosensitive ion channel inner membrane
Transposase IS204/IS1001/IS1096/IS1165 DDE
Aminoacyl-transfer RNA synthetases class-II family profile
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Molybdopterin cofactor biosynthesis C (MoaC)
Bacterial collagen-like protein middle domain-containing protein
Transglycosylase SLT domain-containing protein
Bacterial type II secretion system protein E
Outer-membrane lipoprotein carrier protein
Penicillin-binding protein activator LpoB
Major facilitator superfamily associated
Glucose-methanol-choline oxidoreductase N-terminal
Schiff-base intermediate with substrate; via pyruvic acid
Xaa-Pro dipeptidyl-peptidase-like domain-containing protein
Large ribosomal subunit protein uL15/eL18
Type II secretion system protein GspG C-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Sodium/calcium exchanger membrane region
TIGR02281 family clan AA aspartic protease
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Small ribosomal subunit protein uS4 N-terminal
Positions MEP for the nucleophilic attack
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Right handed beta helix domain-containing protein
Sugar fermentation stimulation protein C-terminal
Membrane fusion protein biotin-lipoyl like
Membrane fusion protein biotin-lipoyl like domain-containing protein
Outer-membrane lipoprotein Wza C-terminal
Outer membrane protein beta-barrel domain-containing protein
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
CopL family metal-binding regulatory protein
ATP synthase F1 complex delta/epsilon subunit N-terminal
HemY N-terminal domain-containing protein
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
DNA replication/recombination mediator RecO N-terminal
Plays an important role in discriminating NADH against NADPH
Mannose-6-phosphate isomerase type II C-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Thiol:disulfide interchange protein DsbA
Resolvase/invertase-type recombinase catalytic
RlpA-like protein double-psi beta-barrel
RNA polymerase sigma factor 70 region 4 type 2
Translocation and assembly module subunit TamA
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Acetyl-CoA hydrolase/transferase C-terminal
Important for substrate binding and specificity
Required for zinc-mediated homotetramerization and catalytic activity
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Involved in allosteric activation by GTP
Pyridine nucleotide-disulphide oxidoreductase dimerisation
YbaK/aminoacyl-tRNA synthetase-associated
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Reversibly protonated during proton transport
Chalcone isomerase domain-containing protein
Pyruvate/ketoisovalerate oxidoreductase catalytic
Thiamine pyrophosphate enzyme TPP-binding
Interaction with polymerase core subunit RpoC
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Thiamin/hydroxymethyl pyrimidine-binding YkoF putative
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Flagellar motor switch protein FliN-like C-terminal
Large ribosomal subunit protein uL6 alpha-beta
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Putative beta-barrel assembly-enhancing protease
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Pseudouridine synthase I TruA alpha/beta
Translation elongation factor EFTs/EF1B dimerisation
Glycosyltransferase subfamily 4-like N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
PilC beta-propeller domain-containing protein
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Sodium symporter small subunit predicted
DNA polymerase III subunit delta C-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Polysaccharide chain length determinant N-terminal
Translation elongation factor P/YeiP central
Superoxide dismutase copper/zinc binding
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Release factor glutamine methyltransferase N-terminal
Putative regulatory protein FmdB Zinc ribbon
NIF system FeS cluster assembly NifU C-terminal
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
YbgF trimerisation domain-containing protein
Penicillin-binding protein activator LpoA
Isocitrate dehydrogenase kinase/phosphatase (AceK) kinase
Isocitrate dehydrogenase kinase/phosphatase (AceK) regulatory
S-adenosyl-L-homocysteine hydrolase NAD binding
Type I restriction modification DNA specificity
Ribosomal RNA adenine methylase transferase N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Pili assembly chaperone N-terminal domain-containing protein
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Glycine zipper 2TM domain-containing protein
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Cobalt-zinc-cadmium resistance protein CzcC
DNA polymerase III delta subunit C-terminal
Thiolase-like protein type 1 additional C-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Heme-copper oxidase subunit III family profile
Interacts with tRNA; defines subfamily-specific binding signature
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Polymerase/histidinol phosphatase N-terminal
EfeO-type cupredoxin-like domain-containing protein
Endolytic peptidoglycan transglycosylase RlpA
Thymidylate synthase/dCMP hydroxymethylase
RNA binding; important for wobble base 34 recognition
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
RNA 2-O ribose methyltransferase substrate binding
Helix-hairpin-helix DNA-binding motif class 1
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Outer membrane protein OmpA-like transmembrane
CobB/CobQ-like glutamine amidotransferase
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
SMP-30/Gluconolactonase/LRE-like region domain-containing protein
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Autotransporter domain-containing protein
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
TtsA-like Glycoside hydrolase family 108
ssDNA thymidine ADP-ribosyltransferase DarT
Chromosomal replication initiator DnaA C-terminal
Outer membrane protein OmpA-like transmembrane domain-containing protein
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
ABC transporter substrate-binding protein
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
CD-NTase associated protein 4-like DNA endonuclease
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Flagellar assembly protein FliH/Type III secretion system HrpE
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Na+/H+ antiporter MnhB subunit-related protein
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Alanyl-transfer RNA synthetases family profile
Alpha-glycerophosphate oxidase C-terminal
Prokaryotic-type class I peptide chain release factors
Prepilin type IV endopeptidase peptidase
Outer membrane protein assembly factor BamA
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Proton acceptor; for glutaminase activity
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Transposase IS116/IS110/IS902 C-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Glucose-methanol-choline oxidoreductase C-terminal
Essential for prephenate dehydratase activity
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Type II secretion system protein GspI C-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-104)
Helix-hairpin-helix DNA-binding motif class 1 domain-containing protein
Lytic transglycosylase superhelical linker
Steroid 5-alpha reductase C-terminal domain-containing protein
Gamma-butyrobetaine hydroxylase-like N-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
Cysteine sulfenic acid (-SOH) intermediate
Beta propeller domain-containing protein
7 transmembrane helices usually fused to an inactive transglutaminase
Inactive transglutaminase fused to 7 transmembrane helices
NAD(P) transhydrogenase alpha subunit C-terminal
Large ribosomal subunit protein uL2 C-terminal
Pilus formation protein N-terminal domain-containing protein
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
4'-phosphopantetheinyl transferase N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Glycosyl transferase family 3 N-terminal
Peptide methionine sulphoxide reductase MsrA
Important for interaction with partner proteins
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Phosphatidic acid phosphatase type 2/haloperoxidase
Alginate export domain-containing protein
Cell envelope integrity inner membrane protein TolA
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Outer membrane protein assembly factor BamB
NADH-rubredoxin oxidoreductase C-terminal
N-end rule aminoacyl transferase C-terminal
Outer membrane lipoprotein-sorting protein
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS domain-containing protein
2,4-diaminopentanoate dehydrogenase C-terminal
Signal transduction histidine kinase internal region
NIF system FeS cluster assembly NifU N-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Calcineurin-like phosphoesterase domain-containing protein
Gly-cisPro motif, important for rejection of L-amino acids
Peptidase M15A C-terminal domain-containing protein
Shikimate dehydrogenase substrate binding N-terminal
Plays an important role in substrate specificity
Exonuclease VII large subunit C-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Carboxylesterase type B domain-containing protein
Could be important to modulate the pK values of the two catalytic cysteine residues
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Phosphoadenosine phosphosulphate reductase
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Chromosomal replication initiator protein DnaA
Polymerase/histidinol phosphatase N-terminal domain-containing protein
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
TonB-dependent receptor plug domain-containing protein
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Putative Flp pilus-assembly TadG-like N-terminal
RNA methyltransferase SpoU/TrmH type C-terminal
Glycine cleavage T-protein C-terminal barrel
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Peptidase C39-like domain-containing protein
Arsenosugar biosynthesis radical SAM protein ArsS-like C-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
May play a role in metal incorporation in vivo
May play a role in transmitting local conformational changes
Polysaccharide biosynthesis protein C-terminal
Type IV secretion system coupling protein TraD DNA-binding
Tyrosine specific protein phosphatases domain-containing protein