Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Type I restriction modification DNA specificity
RNA polymerase sigma factor 70 region 4 type 2
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Resolvase/invertase-type recombinase catalytic
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Phosphatidic acid phosphatase type 2/haloperoxidase
Major facilitator superfamily (MFS) profile
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Tryptophan synthase beta chain-like PALP
N-sulphoglucosamine sulphohydrolase C-terminal
DNA-directed DNA polymerase family A palm
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Aminoacyl-transfer RNA synthetases class-II family profile
Phosphocysteine intermediate; for EIIB activity
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Prokaryotic-type class I peptide chain release factors
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Large ribosomal subunit protein uL15/eL18
ATP synthase F1 complex delta/epsilon subunit N-terminal
Penicillin-binding protein transpeptidase
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Peptide methionine sulphoxide reductase MsrA
Solute-binding protein family 3/N-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Carbamoyl-phosphate synthetase large subunit-like ATP-binding
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Tryptophan RNA-binding attenuator protein
Prepilin type IV endopeptidase peptidase
Positions MEP for the nucleophilic attack
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Alanyl-transfer RNA synthetases family profile
Choloylglycine hydrolase/NAAA C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Survival protein SurE-like phosphatase/nucleotidase
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Gram-positive cocci surface proteins LPxTG
Inosine/uridine-preferring nucleoside hydrolase
DNA mismatch repair proteins mutS family
ABC-type glycine betaine transport system substrate-binding
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Glycoside hydrolase family 42 N-terminal
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Phosphotransferase system enzyme I N-terminal
Anthranilate synthase component I N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Menaquinone biosynthesis protein MenD middle
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Mandelate racemase/muconate lactonizing enzyme C-terminal
Thymidylate synthase/dCMP hydroxymethylase
Cation-transporting P-type ATPase N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
DNA polymerase III delta subunit C-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Helix-hairpin-helix DNA-binding motif class 1
Polymerase/histidinol phosphatase N-terminal
Non-canonical purine NTP phosphatase/PRRC1
Polysaccharide chain length determinant N-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Cytochrome C biogenesis protein transmembrane
Carbamoyl-phosphate synthase small subunit N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Diacylglycerol glucosyltransferase N-terminal
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Transcription factor NikR nickel binding C-terminal
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Beta-xylosidase C-terminal Concanavalin A-like
Microcin J25-processing protein McjB C-terminal
Involved in allosteric activation by GTP
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Cytochrome P460 domain-containing protein
SUF system FeS cluster assembly SufBD N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
DNA replication/recombination mediator RecO N-terminal
Meso-diaminopimelate D-dehydrogenase C-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Phosphoribosylformylglycinamidine synthase linker
D-galactarate/Altronate dehydratase C-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Glyoxalase/fosfomycin resistance/dioxygenase
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Cysteine sulfenic acid (-SOH) intermediate
UDP-glucose/GDP-mannose dehydrogenase C-terminal
N6 adenine-specific DNA methyltransferase N-terminal
ABC transporter substrate-binding protein PnrA-like
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Septum formation inhibitor MinC C-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Lysidine-tRNA(Ile) synthetase C-terminal
Saccharopine dehydrogenase-like C-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Pseudouridine synthase I TruA alpha/beta
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Magnesium transporter MgtE intracellular
Glucosamine/galactosamine-6-phosphate isomerase
Signal transduction histidine kinase internal region
Sporulation transcription regulator WhiA N-terminal
Cell envelope-related transcriptional attenuator
Pyridine nucleotide-disulphide oxidoreductase dimerisation
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Heme-copper oxidase subunit III family profile
Sporulation stage II protein D amidase enhancer LytB N-terminal
Pyrimidine nucleoside phosphorylase C-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Reversibly protonated during proton transport
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Could play a key role in the communication between the regulatory and the substrate sites
Influences the redox potential of the prosthetic heme and FAD groups
Involved in heme-bound ligand stabilization and O-O bond activation
Membrane insertase YidC/Oxa/ALB C-terminal
Cell wall-active antibiotics response LiaF-like C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Lactate utilization protein B C-terminal
Polysaccharide biosynthesis protein C-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
6-phosphogluconate dehydrogenase C-terminal
Schiff-base intermediate with substrate; via pyruvic acid
RNA 2-O ribose methyltransferase substrate binding
Peptidase S9 prolyl oligopeptidase catalytic
Na+/H+ antiporter MnhB subunit-related protein
Glycoside hydrolase family 31 N-terminal
Type III secretion system flagellar brake protein YcgR PilZN
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Integron-associated effector binding protein
Putative Flp pilus-assembly TadG-like N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Ribosomal RNA adenine methylase transferase N-terminal
Alpha-glycerophosphate oxidase C-terminal
TarS beta-glycosyltransferase C-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Superoxide dismutase copper/zinc binding
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Cytochrome b/b6 C-terminal region profile
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Activator of Hsp90 ATPase homologue 1-like C-terminal
Interaction with polymerase core subunit RpoC
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Type VII secretion system protein EssD-like
Thiamin pyrophosphokinase thiamin-binding
Phosphomannose isomerase type I catalytic
Transcription regulator AsnC/Lrp ligand binding
TRAP C4-dicarboxylate transport system permease DctM subunit
Polysaccharide biosynthesis protein CapD-like
Ribose-phosphate pyrophosphokinase N-terminal
Exonuclease VII large subunit C-terminal
Dipicolinate synthase subunit A N-terminal
Probable transposase IS891/IS1136/IS1341
Shikimate dehydrogenase substrate binding N-terminal
Flagellar motor switch protein FliN-like C-terminal
Small ribosomal subunit protein uS4 N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
SMODS-associating 2TM beta-strand rich effector
Large ribosomal subunit protein uL2 C-terminal
Alpha-L-rhamnosidase six-hairpin glycosidase
Important for interaction with partner proteins
Tellurite resistance methyltransferase TehB-like
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
Sporulation stage IV protein A C-terminal
Translation elongation factor P/YeiP central
Gly-cisPro motif, important for rejection of L-amino acids
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
RNA binding; important for wobble base 34 recognition
Important for beta-aspartyl-AMP intermediate formation
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Cytochrome b/b6 N-terminal region profile
Bacterial type II secretion system protein E
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
tRNA pseudouridylate synthase B C-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Schiff-base intermediate with dihydroxyacetone-P
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Single-stranded-DNA-specific exonuclease RecJ C-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Plays an important role in substrate specificity
Schiff-base intermediate with acetaldehyde
Major facilitator superfamily associated
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Antigen I/II N-terminal domain-containing protein
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Glycosyl transferase family 3 N-terminal
Glycoside hydrolase GH146 substrate-binding
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Flagellar hook-length control protein-like C-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Schiff-base intermediate with D-ribose 5-phosphate
Aspartate/homoserine dehydrogenase NAD-binding
Quercetin 2,3-dioxygenase C-terminal cupin
Ionotropic glutamate receptor C-terminal
NIF system FeS cluster assembly NifU N-terminal
Phage conserved hypothetical protein C-terminal