Mandelate racemase/muconate lactonizing enzyme C-terminal
Pyridoxamine 5'-phosphate oxidase putative
Glycoside hydrolase family 31 N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
RNA polymerase sigma factor 70 region 4 type 2
3-keto-disaccharide hydrolase domain-containing protein
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Major facilitator superfamily (MFS) profile
S-adenosyl-L-homocysteine hydrolase NAD binding
Alginate lyase 2 domain-containing protein
Acid phosphatase of HAD superfamily subfamily IIIB
Glycosyltransferase family 28 N-terminal
Peptidase M1 membrane alanine aminopeptidase
Large ribosomal subunit protein uL2 C-terminal
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Schiff-base intermediate with substrate; via pyruvic acid
Aminoacyl-transfer RNA synthetases class-II family profile
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Bacterial bifunctional deaminase-reductase C-terminal
Cell envelope-related transcriptional attenuator
Alpha galactosidase C-terminal beta sandwich
Solute-binding protein family 3/N-terminal
Solute-binding protein family 3/N-terminal domain-containing protein
Peptidase S8/S53 domain-containing protein
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Peptidase C1A papain C-terminal domain-containing protein
Pyrroline-5-carboxylate reductase catalytic N-terminal
Proton acceptor; for glutaminase activity
Transcription regulator AsnC/Lrp ligand binding
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Fibronectin type-III domain-containing protein
Cytochrome b/b6 N-terminal region profile
Tryptophan synthase beta chain-like PALP
RlpA-like protein double-psi beta-barrel
RNA 2-O ribose methyltransferase substrate binding
Peptidase S9 prolyl oligopeptidase catalytic
Phosphoribosylformylglycinamidine synthase linker
Myo-inositol-1-phosphate synthase GAPDH-like
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Transposase IS116/IS110/IS902 C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Periplasmic binding protein domain-containing protein
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Chitin-binding type-3 domain-containing protein
Thiopeptide-type bacteriocin biosynthesis
YbaK/aminoacyl-tRNA synthetase-associated
Cell envelope-related transcriptional attenuator domain-containing protein
Alpha-D-phosphohexomutase alpha/beta/alpha
Erythromycin biosynthesis protein CIII-like central
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Adaptive response protein AidB N-terminal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Elongation factor G-binding protein C-terminal treble-clef zinc-finger
Interaction with polymerase core subunit RpoC
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Membrane insertase YidC/Oxa/ALB C-terminal
Cytochrome C biogenesis protein transmembrane
Molybdenum cofactor biosynthesis protein F N-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Gly-cisPro motif, important for rejection of L-amino acids
Penicillin-binding protein transpeptidase
Cation-transporting P-type ATPase N-terminal
SUF system FeS cluster assembly SufBD N-terminal
Solute-binding protein family 5 domain-containing protein
Acetylserotonin O-methyltransferase dimerisation
Important for beta-aspartyl-AMP intermediate formation
ATP synthase F1 complex delta/epsilon subunit N-terminal
DNA primase/polymerase bifunctional N-terminal
Right handed beta helix domain-containing protein
Glycine cleavage T-protein C-terminal barrel
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
AB hydrolase-1 domain-containing protein
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
6-phosphogluconate dehydrogenase NADP-binding
Prepilin type IV endopeptidase peptidase
Beta-hexosaminidase bacterial type N-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Phosphatidic acid phosphatase type 2/haloperoxidase
Glycosyl hydrolase family 98 putative carbohydrate-binding module
NitT/TauT family transport system substrate-binding protein
SGNH hydrolase-type esterase domain-containing protein
Peptidase M1 membrane alanine aminopeptidase domain-containing protein
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Pyrimidine nucleoside phosphorylase C-terminal
Essential for prephenate dehydratase activity
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
L,D-transpeptidase catalytic domain-containing protein
Large ribosomal subunit protein uL6 alpha-beta
Microcin J25-processing protein McjB C-terminal
tRNA(Ile)-lysidine synthase substrate-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Tyrosine specific protein phosphatases domain-containing protein
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Microcystin LR degradation protein MlrC C-terminal
Microcystin LR degradation protein MlrC N-terminal
Isoglutamyl lysine isopeptide (Glu-Lys) (interchain with K-? in acceptor proteins)
Plays an important role in substrate specificity
Putative oxidoreductase/dehydrogenase Rossmann-like
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Inosine/uridine-preferring nucleoside hydrolase
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
Chitin-binding type-4 domain-containing protein
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Polymerase/histidinol phosphatase N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Small ribosomal subunit protein uS4 N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
DNA replication/recombination mediator RecO N-terminal
Alginate lyase domain-containing protein
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Membrane fusion protein biotin-lipoyl like
Bacterial type II secretion system protein E
1,4-alpha-glucan branching enzyme C-terminal
Glycoside hydrolase family 57 N-terminal
Beta-glucuronidase C-terminal domain-containing protein
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Moybdenum cofactor oxidoreductase dimerisation
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Nicotinate phosphoribosyltransferase N-terminal
Alpha-L-rhamnosidase six-hairpin glycosidase
Helix-hairpin-helix DNA-binding motif class 1
Translation elongation factor P/YeiP central
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Histidine-specific methyltransferase SAM-dependent
Intradiol ring-cleavage dioxygenases domain-containing protein
vWA-MoxR associated protein middle region 0
Prokaryotic-type class I peptide chain release factors
Exonuclease VII large subunit C-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Polysaccharide lyase 8 N-terminal alpha-helical
Polysaccharide lyase family 8 C-terminal
Glycosyl transferase family 28 C-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Beta-lactamase class A catalytic domain-containing protein
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Methylguanine DNA methyltransferase ribonuclease-like
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Nitrate ABC transporter substrate-binding protein
Ricin B lectin domain-containing protein
Alpha-glycerophosphate oxidase C-terminal
Glycosyl transferase family 3 N-terminal
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal domain-containing protein
Anthranilate synthase component I N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Methionyl-tRNA synthetase anticodon-binding
EfeO-type cupredoxin-like domain-containing protein
Activator of Hsp90 ATPase homologue 1-like C-terminal
ABC-type glycine betaine transport system substrate-binding
Putative glycogen debranching enzyme N-terminal
Lantibiotic biosynthesis protein dehydration
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
DNA-directed DNA polymerase family A palm
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Gp5/Type VI secretion system Vgr protein OB-fold
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Polysaccharide chain length determinant N-terminal
Removed in mature form; by autocatalysis
Homogentisate 1,2-dioxygenase N-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Cell wall-active antibiotics response LiaF-like C-terminal
Diacylglycerol glucosyltransferase N-terminal
Fe/B12 periplasmic-binding domain-containing protein
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
SsuA/THI5-like domain-containing protein
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Peptidase M14 carboxypeptidase A domain-containing protein
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose 2,3-dehydratase
Alpha-L-fucosidase C-terminal domain-containing protein
Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminal
Could play a key role in the communication between the regulatory and the substrate sites
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Glycoside-hydrolase family GH114 TIM-barrel
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Asl1-like glycosyl hydrolase catalytic domain-containing protein
Putative regulatory protein FmdB Zinc ribbon
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal domain-containing protein
Cysteine sulfenic acid (-SOH) intermediate
Glycoside hydrolase family 5 domain-containing protein
Positions MEP for the nucleophilic attack
Peptidase M15C domain-containing protein
Peptidoglycan binding-like domain-containing protein
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Carbamoyl-phosphate synthase small subunit N-terminal
Carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding protein
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Styrene monooxygenase StyA putative substrate binding
4'-phosphopantetheinyl transferase N-terminal
Phosphotransferase system enzyme I N-terminal
Polynucleotide kinase-phosphatase C-terminal
Polynucleotide kinase-phosphatase ligase
Aromatic amino acid beta-eliminating lyase/threonine aldolase
ssDNA thymidine ADP-ribosyltransferase DarT
Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase C-terminal
Gamma-glutamylcyclotransferase AIG2-like
Superoxide dismutase copper/zinc binding domain-containing protein
Prealbumin-like fold domain-containing protein
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Lipocalin-like domain-containing protein
Actinobacteria/chloroflexi VLRF1 release factor
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Calcineurin-like phosphoesterase domain-containing protein
Septum formation-related domain-containing protein
Peptidase S1A alpha-lytic prodomain domain-containing protein
Peptidase C39-like domain-containing protein
Sporulation transcription regulator WhiA N-terminal
Contractile injection system tube protein N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
May play a role in metal incorporation in vivo
May play a role in transmitting local conformational changes
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Resuscitation-promoting factor core lysozyme-like
LamG-like jellyroll fold domain-containing protein
Glycoside-hydrolase family GH114 TIM-barrel domain-containing protein
Pseudouridine synthase I TruA alpha/beta
Phosphomannose isomerase type I catalytic
Endoribonuclease L-PSP/chorismate mutase-like
Sugar ABC transporter substrate-binding protein
Lactate utilization protein B C-terminal
Subtilisin inhibitor domain-containing protein
Glutathionylspermidine synthase pre-ATP-grasp-like
Sulfatase N-terminal domain-containing protein
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
PhoD-like phosphatase metallophosphatase
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Glucose/Sorbosone dehydrogenase domain-containing protein
Cellulase Ig-like domain-containing protein
NADH:ubiquinone oxidoreductase 30kDa subunit
Pyrroline-5-carboxylate reductase dimerisation
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
6-phosphogluconate dehydrogenase C-terminal
Chromosomal replication initiator DnaA C-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Quercetin 2,3-dioxygenase C-terminal cupin
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Bulb-type lectin domain-containing protein
NIF system FeS cluster assembly NifU N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Alanyl-transfer RNA synthetases family profile
Leucine-binding protein domain-containing protein
Release factor glutamine methyltransferase N-terminal
Conserved hypothetical protein CHP02679 N terminus
Heat-inducible transcription repressor HrcA C-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
ABC-type glycine betaine transport system substrate-binding domain-containing protein
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Glucosamine/galactosamine-6-phosphate isomerase
Peptidoglycan recognition protein family