Pyridine nucleotide-disulphide oxidoreductase dimerisation
O-(5'-phospho-DNA)-tyrosine intermediate
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Membrane insertase YidC/Oxa/ALB C-terminal
Outer membrane protein beta-barrel domain-containing protein
Cytochrome b561 bacterial/Ni-hydrogenase
Phosphatidic acid phosphatase type 2/haloperoxidase
Major facilitator superfamily (MFS) profile
Aminoacyl-transfer RNA synthetases class-II family profile
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Large ribosomal subunit protein uL6 alpha-beta
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Flagellar hook-length control protein-like C-terminal
Anti-bacteriophage protein A/HamA C-terminal
Mannose-6-phosphate isomerase type II C-terminal
Peptide methionine sulphoxide reductase MsrA
Heme-copper oxidase subunit III family profile
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Membrane fusion protein biotin-lipoyl like
Solute-binding protein family 3/N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
SMODS-associated and fused to various effectors
Sialate O-acetylesterase domain-containing protein
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
ABC transporter substrate-binding protein
Sugar fermentation stimulation protein C-terminal
6-phosphogluconate dehydrogenase NADP-binding
Phosphogluconate dehydrogenase NAD-binding putative C-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
Bacterial type II secretion system protein E
Phenol hydroxylase C-terminal dimerisation
Acyl-CoA dehydrogenase/oxidase N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Flagellar motor switch protein FliN-like C-terminal
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
Tryptophan synthase beta chain-like PALP
Ricin B lectin domain-containing protein
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
Glycoside hydrolase family 31 N-terminal
Pesticidal crystal protein Cry22Aa Ig-like
Pesticidal crystal protein Cry22Aa Ig-like domain-containing protein
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Ionotropic glutamate receptor C-terminal
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Quercetin 2,3-dioxygenase C-terminal cupin
Extradiol ring-cleavage dioxygenase LigAB LigA subunit
Glycosyltransferase subfamily 4-like N-terminal
Fibronectin type-III domain-containing protein
Isocitrate dehydrogenase kinase/phosphatase (AceK) kinase
Isocitrate dehydrogenase kinase/phosphatase (AceK) regulatory
ABC-type transport auxiliary lipoprotein component
Type 4 fimbrial biogenesis protein PilX N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Diiron non-heme beta-hydroxylase N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Electron transfer flavoprotein alpha/beta-subunit N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
RND efflux pump membrane fusion protein barrel-sandwich
Penicillin-binding protein transpeptidase
RNA polymerase sigma factor 70 region 4 type 2
Pyrimidine nucleoside phosphorylase C-terminal
Lipocalin-like domain-containing protein
Cysteine sulfenic acid (-SOH) intermediate
4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase-like C-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Magnesium transporter MgtE intracellular
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Polysaccharide chain length determinant N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
S-adenosyl-L-homocysteine hydrolase NAD binding
Carbohydrate-binding/sugar hydrolysis domain-containing protein
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
SUF system FeS cluster assembly SufBD N-terminal
Glycine cleavage T-protein C-terminal barrel
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Nicotinamide phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Dinitrogenase iron-molybdenum cofactor N-terminal
Dinitrogenase iron-molybdenum cofactor biosynthesis
Carbamoyl-phosphate synthase small subunit N-terminal
RNA 2-O ribose methyltransferase substrate binding
Putative adhesin domain-containing protein
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Cytochrome C biogenesis protein transmembrane
Thiol:disulfide interchange protein DsbD N-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-106)
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Prepilin type IV endopeptidase peptidase
Interaction with polymerase core subunit RpoC
Glyoxalase/fosfomycin resistance/dioxygenase
DNA polymerase III subunit delta C-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Acyl-CoA dehydrogenase/oxidase C-terminal
Urease accessory protein UreH-like transmembrane
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Contractile injection system tube protein N-terminal
Reversibly protonated during proton transport
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Resolvase/invertase-type recombinase catalytic
Signal transduction histidine kinase internal region
Plays an important role in substrate specificity
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Outer membrane lipoprotein carrier protein LolA
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Cytochrome c7-like domain-containing protein
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
SGNH hydrolase-type esterase domain-containing protein
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Lysine-specific metallo-endopeptidase domain-containing protein
PhoD-like phosphatase metallophosphatase
Ribose-phosphate pyrophosphokinase N-terminal
Alpha-glycerophosphate oxidase C-terminal
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-91)
Thymidylate synthase/dCMP hydroxymethylase
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
TonB-dependent receptor-like beta-barrel
Glucose-methanol-choline oxidoreductase C-terminal
Type VI secretion system IcmF C-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Exonuclease VII large subunit C-terminal
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Large ribosomal subunit protein uL15/eL18
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Right handed beta helix domain-containing protein
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Translation elongation factor P/YeiP central
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Chromosomal replication initiator protein DnaA
Ribonucleotide reductase large subunit C-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Flagella basal body P-ring formation protein FlgA C-terminal
Glucosamine/galactosamine-6-phosphate isomerase
L,D-transpeptidase catalytic domain-containing protein
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
CobB/CobQ-like glutamine amidotransferase
Pyruvate phosphate dikinase AMP/ATP-binding
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Threonine/serine exporter-like N-terminal
DNA polymerase III delta subunit C-terminal
Flagella basal body P-ring formation protein FlgA
Could play a key role in the communication between the regulatory and the substrate sites
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
Jacalin-type lectin domain-containing protein
Signal transduction histidine kinase 5TM receptor LytS transmembrane region
NIF system FeS cluster assembly NifU C-terminal
S-adenosylmethionine-dependent methyltransferase
Glycoside-hydrolase family GH114 TIM-barrel
Flagellar Assembly Protein A N-terminal region
YbaK/aminoacyl-tRNA synthetase-associated
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
Disulphide bond isomerase DsbC/G N-terminal
Rhamnogalacturonan lyase domain-containing protein
ABC-type amino acid transport/signal transduction system, periplasmic component/domain
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Water stress and hypersensitive response
Adaptive response protein AidB N-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Beta-lactamase hydrolase-like protein phosphatase-like
Alginate export domain-containing protein
Peptidase M15A C-terminal domain-containing protein
Chromosomal replication initiator DnaA C-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Peptidase S9 prolyl oligopeptidase catalytic
Alanyl-transfer RNA synthetases family profile
N6 adenine-specific DNA methyltransferase N-terminal
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Translocation and assembly module subunit TamA
Gp5/Type VI secretion system Vgr protein OB-fold
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
DNA-directed DNA polymerase family A palm
TtsA-like Glycoside hydrolase family 108
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
1-phosphatidylinositol phosphodiesterase
Phosphatidylinositol-specific phospholipase C X
Glycosyl transferase family 3 N-terminal
DNA-3-methyladenine glycosylase AlkA N-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Required for dimer formation and molybdate binding
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Small ribosomal subunit protein uS4 N-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
ABC transporter substrate-binding protein PnrA-like
Molybdopterin cofactor biosynthesis C (MoaC)
Erythronate-4-phosphate dehydrogenase dimerisation
ABC-type glycine betaine transport system substrate-binding
Polymerase/histidinol phosphatase N-terminal
Phosphocysteine intermediate; for EIIB activity
4'-phosphopantetheinyl transferase N-terminal
Electron transfer via tryptophanyl radical
Essential for prephenate dehydratase activity
Gamma-glutamylcyclotransferase AIG2-like
Bacterial bifunctional deaminase-reductase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Hydroxymethylglutaryl-coenzyme A synthase C-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
Periplasmic nitrate reductase, electron transfer subunit
UDP N-acetylglucosamine O-acyltransferase C-terminal
Sodium symporter small subunit predicted
Histidine-specific methyltransferase SAM-dependent
Arginine decarboxylase C-terminal helical
Glutathionylspermidine synthase pre-ATP-grasp-like
Pyruvate dehydrogenase E1 component middle
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Putative auto-transporter adhesin head GIN
Putative auto-transporter adhesin head GIN domain-containing protein
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
6-phosphogluconate dehydrogenase C-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Glycosyl hydrolases family 2 sugar binding
DNA mismatch repair proteins mutS family
Alpha-D-phosphohexomutase alpha/beta/alpha
Glucose-methanol-choline oxidoreductase N-terminal
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
Gamma-butyrobetaine hydroxylase-like N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Cellulase Ig-like domain-containing protein
Shikimate dehydrogenase substrate binding N-terminal
Large ribosomal subunit protein uL2 C-terminal
Anthranilate synthase component I N-terminal
Prokaryotic-type class I peptide chain release factors
Sec translocon accessory complex subunit YajC
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Transposase IS204/IS1001/IS1096/IS1165 DDE
Pyridoxamine 5'-phosphate oxidase putative
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Putative glycogen debranching enzyme N-terminal
RNA methyltransferase SpoU/TrmH type C-terminal
Plays an important role in discriminating NADH against NADPH
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Chalcone isomerase domain-containing protein
Caspase family p20 domain-containing protein
Important for interaction with partner proteins
Transcription regulator AsnC/Lrp ligand binding
Sulfatase-modifying factor enzyme domain-containing protein
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Important for beta-aspartyl-AMP intermediate formation
Inner membrane protein YgaP-like transmembrane
Aminoacyl-tRNA synthetase class I anticodon-binding
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Nitrogenase molybdenum-iron protein beta chain N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Type II secretion system protein GspI C-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
NIF system FeS cluster assembly NifU N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Carboxypeptidase regulatory-like domain-containing protein