Type II secretion system protein GspG C-terminal
Release factor glutamine methyltransferase N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Major facilitator superfamily (MFS) profile
Molybdopterin cofactor biosynthesis C (MoaC)
TonB-dependent receptor-like beta-barrel
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Transcriptional regulator SgrR N-terminal HTH
Phosphocysteine intermediate; for EIIB activity
Sodium/calcium exchanger membrane region
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Bacterial OB-fold domain-containing protein
Inosine/uridine-preferring nucleoside hydrolase
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Sugar fermentation stimulation protein C-terminal
Fimbrial-type adhesion domain-containing protein
YdgH/BhsA/McbA-like domain-containing protein
Cytochrome c-type biogenesis protein CcmF C-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Lysozyme inhibitor LprI N-terminal domain-containing protein
Pyruvate dehydrogenase E1 component middle
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
Polysaccharide biosynthesis protein C-terminal
Bacterial type II secretion system protein E
Important for substrate binding and specificity
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Heme-copper oxidase subunit III family profile
Alpha-L-rhamnosidase six-hairpin glycosidase
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
DNA-directed DNA polymerase family A palm
Thiol:disulfide interchange protein DsbD N-terminal
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
4'-phosphopantetheinyl transferase N-terminal
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Phosphatidic acid phosphatase type 2/haloperoxidase
O-(5'-phospho-DNA)-tyrosine intermediate
Gp5/Type VI secretion system Vgr protein OB-fold
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
DNA polymerase III delta subunit C-terminal
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Proton acceptor; for decarboxylase activity
Proton donor; for decarboxylase activity
Proton donor; for formyltransferase activity
Proton acceptor; for glutaminase activity
Glycosyltransferase subfamily 4-like N-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Transposase IS116/IS110/IS902 C-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
SUF system FeS cluster assembly SufBD N-terminal
Schiff-base intermediate with acetaldehyde
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Outer membrane protein assembly factor BamA
Glycosyl transferase family 3 N-terminal
Flagellar motor switch protein FliN N-terminal
Flagellar motor switch protein FliN-like C-terminal
HicB-like antitoxin of toxin-antitoxin system
RND efflux pump membrane fusion protein barrel-sandwich
Type VI secretion system IcmF C-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Large ribosomal subunit protein uL15/eL18
Helix-hairpin-helix DNA-binding motif class 1
Interaction with polymerase core subunit RpoC
Autotransporter domain-containing protein
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
6-phosphogluconate dehydrogenase NADP-binding
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
Sporulation stage II protein D amidase enhancer LytB N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Polysaccharide chain length determinant N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Outer membrane protein assembly factor BamB
Tryptophan synthase beta chain-like PALP
UDP-glucose/GDP-mannose dehydrogenase C-terminal
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
Nitrite/Sulfite reductase ferredoxin-like
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Required for dimer formation and molybdate binding
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Prokaryotic-type class I peptide chain release factors
Aconitase A/isopropylmalate dehydratase small subunit swivel
O-(3'-phospho-DNA)-tyrosine intermediate
Large ribosomal subunit protein uL2 C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
Glucose-6-phosphate isomerase prokaryote
Interacts with tRNA; defines subfamily-specific binding signature
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Pyrimidine nucleoside phosphorylase C-terminal
Type I restriction modification DNA specificity
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
Tetrahydrodipicolinate-N-succinyltransferase chain A
Solute-binding protein family 3/N-terminal domain-containing protein
D-galactose/methyl-galactoside binding periplasmic protein MglB
Penicillin-binding protein transpeptidase
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Mandelate racemase/muconate lactonizing enzyme C-terminal
Alpha-1,6-glucosidases pullulanase-type C-terminal
Glycoside hydrolase family 13 N-terminal
Pullulanase carbohydrate-binding module 41
Exonuclease VII large subunit C-terminal
Prepilin type IV endopeptidase peptidase
Could be important to modulate the pK values of the two catalytic cysteine residues
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Antitoxin Xre/MbcA/ParS-like toxin-binding
Lysidine-tRNA(Ile) synthetase C-terminal
RNA polymerase sigma factor 70 region 4 type 2
Menaquinone biosynthesis protein MenD middle
Chromosomal replication initiator protein DnaA
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Alpha-glycerophosphate oxidase C-terminal
Flagellar hook-length control protein-like C-terminal
Superoxide dismutase copper/zinc binding
Polymerase/histidinol phosphatase N-terminal
Organic solvent tolerance-like N-terminal
Essential for degradation by Lon protease
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
ABC-type transport auxiliary lipoprotein component
Guanylate kinase/L-type calcium channel beta subunit
Pilus assembly protein E-set like domain-containing protein
Phosphoethanolamine transferase N-terminal
May play a role in metal incorporation in vivo
May play a role in transmitting local conformational changes
Greasy slide, important in sugar transport
RNA 2-O ribose methyltransferase substrate binding
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Penicillin-binding protein activator LpoA
Non-canonical purine NTP phosphatase/PRRC1
Ribosomal RNA adenine methylase transferase N-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Acyl-ester intermediate; for transpeptidase activity
Proton donor; for transglycosylase activity
Transglycosylase PBP1b N-terminal transmembrane
ATP synthase F1 complex delta/epsilon subunit N-terminal
Glycosyl transferase family 28 C-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Gly-cisPro motif, important for rejection of L-amino acids
Flagellar assembly protein FliH/Type III secretion system HrpE
Pili assembly chaperone N-terminal domain-containing protein
Contractile injection system tube protein N-terminal
Interaction with tRNA; Important for base-flipping
Pseudouridine synthase I TruA alpha/beta
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Lambda-like tail fibre protein N-terminal
Proline utilization A proline dehydrogenase N-terminal
Appears to be important in orienting the phosphate for catalysis
Membrane fusion protein biotin-lipoyl like
TRAP C4-dicarboxylate transport system permease DctM subunit
Essential for prephenate dehydratase activity
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Plays an important role in discriminating NADH against NADPH
Cysteine sulfenic acid (-SOH) intermediate
Activator of Hsp90 ATPase homologue 1-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Glucosamine/galactosamine-6-phosphate isomerase
NIF system FeS cluster assembly NifU C-terminal
Flagella basal body P-ring formation protein FlgA
Periplasmic nitrate reductase, electron transfer subunit
Phosphoadenosine phosphosulphate reductase
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
DNA polymerase III subunit delta C-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Lipopolysaccharide export system protein LptA
Spore coat protein U domain-containing protein
Regulator of nucleoside diphosphate kinase N-terminal
Transcription elongation factor GreA/GreB C-terminal
Influences the redox potential of the prosthetic heme and FAD groups
Involved in heme-bound ligand stabilization and O-O bond activation
Translocation and assembly module subunit TamA
Pyruvate phosphate dikinase AMP/ATP-binding
Nucleophile; cysteine thiosulfonate intermediate
RNA binding; important for wobble base 34 recognition
Transcription elongation factor GreA/GreB N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
6-phosphogluconate dehydrogenase C-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Cob(I)alamin adenosyltransferase N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
DNA mismatch repair proteins mutS family
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Integral membrane protein YccS N-terminal
Type II secretion system protein GspI C-terminal
Major facilitator superfamily associated
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Membrane-bound lytic murein transglycosylase C
Phosphomannose isomerase type I C-terminal
Phosphomannose isomerase type I catalytic
Phosphomannose isomerase type I helical insertion
Glutathionylspermidine synthase pre-ATP-grasp-like
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Calcium/calmodulin-dependent protein kinase II association-domain
Translation elongation factor P/YeiP central
Large ribosomal subunit protein uL6 alpha-beta
Molybdenum cofactor biosynthesis protein F N-terminal
Glycoside hydrolase family 31 N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Plays a key role in the stabilization of the transition state and positioning the aldehyde component
Acyl-CoA dehydrogenase/oxidase C-terminal
Adaptive response protein AidB N-terminal
Aspartate/homoserine dehydrogenase NAD-binding
Bacterial transcription activator effector binding
Phospholipase/carboxylesterase/thioesterase domain-containing protein
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Carbamoyl-phosphate synthase small subunit N-terminal
Electron transfer via tryptophanyl radical
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Chromosome partition protein MukF C-terminal
Chromosome partition protein MukF middle
Chromosome partition protein MukF winged-helix
Negative modulator of initiation of replication SeqA N-terminal
Replication modulator SeqA C-terminal DNA-binding
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
SMP-30/Gluconolactonase/LRE-like region domain-containing protein
Threonine/serine exporter-like N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Outer membrane protein assembly factor BamE
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
For 3-hydroxyacyl-CoA dehydrogenase activity
Outer membrane lipoprotein-sorting protein
Survival protein SurE-like phosphatase/nucleotidase
Chitobiase/beta-hexosaminidases N-terminal
Alanyl-transfer RNA synthetases family profile
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Phosphotransferase system enzyme I N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Mechanosensitive ion channel inner membrane
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
High-affinity zinc uptake system protein ZnuA
Plays an important role in substrate specificity
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Reversibly protonated during proton transport
Anti-bacteriophage protein A/HamA C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Endolytic peptidoglycan transglycosylase RlpA
Type IV secretion system coupling protein TraD DNA-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
DNA replication/recombination mediator RecO N-terminal
DNA mismatch repair MutH/Type II restriction enzyme Sau3AI
Integron-associated effector binding protein
Fe/B12 periplasmic-binding domain-containing protein
ABC-type glycine betaine transport system substrate-binding
Positions MEP for the nucleophilic attack
NADH:ubiquinone oxidoreductase 30kDa subunit
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Glucose-methanol-choline oxidoreductase C-terminal
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Arginine decarboxylase C-terminal helical
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
NIF system FeS cluster assembly NifU N-terminal
Important for beta-aspartyl-AMP intermediate formation
Cation-transporting P-type ATPase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Involved in allosteric activation by GTP
Terminase large subunit gp17-like C-terminal
Seems to be a necessary countercharge to the potassium cations
Important for interaction with partner proteins
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Beta-hexosaminidase bacterial type N-terminal
Curli production assembly/transport component CsgG
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Membrane insertase YidC/Oxa/ALB C-terminal
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Ricin B lectin domain-containing protein
L-seryl-tRNA selenium transferase N-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Thymidylate synthase/dCMP hydroxymethylase
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Common pilus major fimbrillin subunit EcpA
Anthranilate synthase component I N-terminal
Type II secretion system protein GspC N-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Acyl-CoA dehydrogenase C-terminal bacterial-type
Acyl-CoA dehydrogenase/oxidase N-terminal
Outer-membrane lipoprotein Wza C-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Erythronate-4-phosphate dehydrogenase dimerisation
Required for zinc-mediated homotetramerization and catalytic activity
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Glycine cleavage T-protein C-terminal barrel
Outer membrane protein assembly factor BamD
Isocitrate dehydrogenase kinase/phosphatase (AceK) kinase
Isocitrate dehydrogenase kinase/phosphatase (AceK) regulatory
Glycosyltransferase family 28 N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Small ribosomal subunit protein uS4 N-terminal
Periplasmic binding protein/LacI sugar binding
The binding site for the sugar molecule has not yet been established, but C-87 may be involved
Electron transfer flavoprotein alpha/beta-subunit N-terminal