Putative oxidoreductase/dehydrogenase Rossmann-like
Hydroxymethylglutaryl-coenzyme A synthase C-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Ribose-phosphate pyrophosphokinase N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Glycosyltransferase subfamily 4-like N-terminal
Major facilitator superfamily (MFS) profile
Aconitase A/isopropylmalate dehydratase small subunit swivel
Sporulation transcription regulator WhiA N-terminal
Polymerase/histidinol phosphatase N-terminal
Fe/B12 periplasmic-binding domain-containing protein
Bacterial type II secretion system protein E
Small ribosomal subunit protein uS4 N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Prokaryotic-type class I peptide chain release factors
RNA 2-O ribose methyltransferase substrate binding
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Meso-diaminopimelate D-dehydrogenase C-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Alanyl-transfer RNA synthetases family profile
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Essential for prephenate dehydratase activity
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Nitrite/Sulfite reductase ferredoxin-like
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Important for substrate specificity; cannot use PPi as phosphoryl donor
Alpha-D-phosphohexomutase alpha/beta/alpha
TRAP C4-dicarboxylate transport system permease DctM subunit
Glycine cleavage T-protein C-terminal barrel
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Galactofuranosyltransferase GlfT2 N-terminal
Galactofuranosyltransferase-2 C-terminal
Pyridoxamine 5'-phosphate oxidase putative
Inner membrane protein YgaP-like transmembrane
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Cytochrome b/b6 N-terminal region profile
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
O-(5'-phospho-DNA)-tyrosine intermediate
Solute-binding protein family 3/N-terminal
Solute-binding protein family 3/N-terminal domain-containing protein
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Type II secretion system protein GspF domain-containing protein
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Large ribosomal subunit protein uL2 C-terminal
Large ribosomal subunit protein uL15/eL18
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Resuscitation-promoting factor core lysozyme-like
Resuscitation-promoting factor core lysozyme-like domain-containing protein
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Ribosome maturation factor RimP N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Inosine/uridine-preferring nucleoside hydrolase
Important for beta-aspartyl-AMP intermediate formation
Polysaccharide chain length determinant N-terminal
Cell envelope-related transcriptional attenuator
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
CobB/CobQ-like glutamine amidotransferase
Glucosamine/galactosamine-6-phosphate isomerase
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
DNA primase/polymerase bifunctional N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Pyrimidine nucleoside phosphorylase C-terminal
Gly-cisPro motif, important for rejection of L-amino acids
6-phosphogluconate dehydrogenase C-terminal
Peptidoglycan recognition protein family
Large ribosomal subunit protein uL30-like ferredoxin-like fold
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Heat-inducible transcription repressor HrcA C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Myo-inositol-1-phosphate synthase GAPDH-like
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Resolvase/invertase-type recombinase catalytic
Solute-binding protein family 5 domain-containing protein
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Cytochrome oxidase subunit II copper A binding
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
YbaK/aminoacyl-tRNA synthetase-associated
RNA polymerase sigma factor 70 region 4 type 2
ABC transporter substrate-binding protein
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Increases nucleophilicity of active site Cys
Phosphocysteine intermediate; for EIIB activity
Tryptophan synthase beta chain-like PALP
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Schiff-base intermediate with acetaldehyde
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Arabinofuranosyltransferase AftA C-terminal
Arabinofuranosyltransferase AftA N-terminal
ATP-dependent DNA helicase RecG C-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Schiff-base intermediate with substrate; via pyruvic acid
Cysteine sulfenic acid (-SOH) intermediate
Cytochrome b561 bacterial/Ni-hydrogenase
Phosphotransferase system enzyme I N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
ABC-type glycine betaine transport system substrate-binding
NADH:flavin oxidoreductase/NADH oxidase N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Penicillin-binding protein transpeptidase
Methionyl-tRNA synthetase anticodon-binding
Prealbumin-like fold domain-containing protein
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Involved in ionization of N3 of dUMP, leading to its activation
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
ATP synthase F1 complex delta/epsilon subunit N-terminal
Mycothiol-dependent maleylpyruvate isomerase metal-binding
NIF system FeS cluster assembly NifU N-terminal
Putative host cell surface-exposed lipoprotein Ltp-like HTH region
Plays an important role in substrate specificity
Isoglutamyl lysine isopeptide (Glu-Lys) (interchain with K-? in acceptor proteins)
Shikimate dehydrogenase substrate binding N-terminal
RNA binding; important for wobble base 34 recognition
Translation elongation factor P/YeiP central
Peptide methionine sulphoxide reductase MsrA
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Neutral/alkaline non-lysosomal ceramidase C-terminal
Neutral/alkaline non-lysosomal ceramidase N-terminal
Exonuclease VII large subunit C-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Cytochrome C biogenesis protein transmembrane
Peptidase M1 membrane alanine aminopeptidase
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Large ribosomal subunit protein uL6 alpha-beta
Alpha-glycerophosphate oxidase C-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Endoribonuclease L-PSP/chorismate mutase-like
Gram-positive pilin subunit D1 N-terminal
Gram-positive pilin subunit D1 N-terminal domain-containing protein
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
O-(3'-phospho-DNA)-tyrosine intermediate
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Reversibly protonated during proton transport
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
SGNH hydrolase-type esterase domain-containing protein