Aminoacyl-transfer RNA synthetases class-II family profile
RNA 3'-terminal phosphate cyclase insert
SAM-dependent methyltransferase TRM5/TYW2-type
BREX system Lon protease-like BrxL N-terminal
Aldehyde ferredoxin oxidoreductase N-terminal
Plays an important role in substrate specificity
Major facilitator superfamily (MFS) profile
Pyruvate/ketoisovalerate oxidoreductase catalytic
Glycosyltransferase subfamily 4-like N-terminal
Siroheme decarboxylase AsnC-like ligand binding
NADH:ubiquinone oxidoreductase 30kDa subunit
Methyl-coenzyme M reductase alpha subunit C-terminal
Methyl-coenzyme M reductase alpha subunit N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
ATP-dependent DNA helicase RecG C-terminal
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
Transcription factor NikR nickel binding C-terminal
Methanogenesis regulatory protein FilR1 middle
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal
Coenzyme F420 hydrogenase/dehydrogenase beta subunit N-terminal
DNA mismatch repair proteins mutS family
Histidine-specific methyltransferase SAM-dependent
Cytochrome C biogenesis protein transmembrane
Small ribosomal subunit protein uS4 N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Type I restriction modification DNA specificity
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Ribose-phosphate pyrophosphokinase N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Formylmethanofuran dehydrogenase subunit E
Translation elongation factor IF5A C-terminal
Polysaccharide biosynthesis protein C-terminal
Removed in mature form; by autocatalysis
Small ribosomal subunit protein uS15 N-terminal
Gamma-glutamylcyclotransferase AIG2-like
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
HicB-like antitoxin of toxin-antitoxin system
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Ribosome maturation protein SDO1/SBDS C-terminal
Ribosome maturation protein SDO1/SBDS N-terminal
Ribosome maturation protein SDO1/SBDS central
Glycogen debranching enzyme bacterial and archaeal type N-terminal
Bacterial type II secretion system protein E
Myo-inositol-1-phosphate synthase GAPDH-like
N6 adenine-specific DNA methyltransferase N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Aspartate/homoserine dehydrogenase NAD-binding
Tryptophan synthase beta chain-like PALP
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Large ribosomal subunit protein uL6 alpha-beta
Transposase IS116/IS110/IS902 C-terminal
tRNA nucleotidyltransferase substrate binding
CO dehydrogenase/acetyl-CoA synthase complex beta subunit C-terminal
Polysaccharide biosynthesis protein CapD-like
Actinobacteria/chloroflexi VLRF1 release factor
Restriction system protein Mrr-like N-terminal
Archaeal glycosylation protein B peripheral
Cation-transporting P-type ATPase N-terminal
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-96)
Schiff-base intermediate with dihydroxyacetone-P
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Pyridoxamine 5'-phosphate oxidase putative
Dinitrogenase iron-molybdenum cofactor biosynthesis
Phosphatidylglycerol lysyltransferase C-terminal
Archaetidylserine decarboxylase alpha chain
Archaetidylserine decarboxylase beta chain
Cleavage (non-hydrolytic); by autocatalysis
Schiff-base intermediate with substrate; via pyruvic acid
Phosphatidic acid phosphatase type 2/haloperoxidase
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr C-terminal
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr N-terminal
CO dehydrogenase/acetyl-CoA synthase delta subunit TIM barrel
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Pyruvoyl-dependent arginine decarboxylase subunit alpha
Pyruvoyl-dependent arginine decarboxylase subunit beta
RNA polymerase subunit H/Rpb5 C-terminal
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
Glucose-6-phosphate isomerase prokaryote
S-adenosyl-L-homocysteine hydrolase NAD binding
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
DNA polymerase II large subunit DP2 N-terminal
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Signal transduction histidine kinase subgroup 2 dimerisation and phosphoacceptor
Large ribosomal subunit protein uL10-like insertion
Alpha-D-phosphohexomutase alpha/beta/alpha
Translation elongation factor EF1B beta/delta subunit guanine nucleotide exchange
ATP synthase F1 complex delta/epsilon subunit N-terminal
Sodium/calcium exchanger membrane region
Pyrimidine nucleoside phosphorylase C-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Nitrite/Sulfite reductase ferredoxin-like
NIF system FeS cluster assembly NifU N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Pyruvate phosphate dikinase AMP/ATP-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Small zinc finger protein HVO-2753-like zinc-binding pocket
Cytochrome c-type biogenesis protein CcmF C-terminal
Transcription regulator AsnC/Lrp ligand binding
Saccharopine dehydrogenase-like C-terminal
Polymerase/histidinol phosphatase N-terminal
Dihydroneopterin aldolase MtpD C-terminal
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Pyrroline-5-carboxylate reductase catalytic N-terminal
Glycoside hydrolase family 57 N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Anthranilate synthase component I N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Na+/H+ antiporter MnhB subunit-related protein
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Alanyl-transfer RNA synthetases family profile
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
DNA-directed RNA polymerase subunit 2 hybrid-binding
DNA polymerase alpha/delta/epsilon subunit B
ABC-type glycine betaine transport system substrate-binding
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Damage-control phosphatase ARMT1-like metal-binding
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Large ribosomal subunit protein uL30-like ferredoxin-like fold
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Periplasmic copper-binding protein NosD beta helix
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Methyl-coenzyme M reductase beta subunit C-terminal
Methyl-coenzyme M reductase beta subunit N-terminal
Large ribosomal subunit protein uL15/eL18
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Pseudouridine synthase I TruA alpha/beta
DNA-directed DNA polymerase family B mitochondria/virus
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
16S/18S rRNA aminocarboxypropyltransferase Tsr3 C-terminal
RNase L inhibitor RLI-like possible metal-binding
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Schiff-base intermediate with D-ribose 5-phosphate
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Large ribosomal subunit protein uL2 C-terminal
Glycosyl transferase family 28 C-terminal
Phosphoribosylformylglycinamidine synthase linker
Spo11/DNA topoisomerase VI subunit A N-terminal
Helix-hairpin-helix DNA-binding motif class 1
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Methylene-tetrahydrofolate reductase C-terminal
Tetrahydromethanopterin S-methyltransferase F subunit
DNA-directed RNA polymerase RBP11-like dimerisation
Proliferating cell nuclear antigen PCNA C-terminal
Proliferating cell nuclear antigen PCNA N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Glutamate synthase alpha subunit C-terminal
Prepilin type IV endopeptidase peptidase
Mannose-6-phosphate isomerase type II C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate