Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Polysaccharide biosynthesis protein C-terminal
Polymerase/histidinol phosphatase N-terminal
Peptidase M1 membrane alanine aminopeptidase
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Large ribosomal subunit protein bL9 C-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Plays an important role in substrate specificity
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Tryptophan synthase beta chain-like PALP
Pyruvate/ketoisovalerate oxidoreductase catalytic
TRAP C4-dicarboxylate transport system permease DctM subunit
5-glutamyl coenzyme A thioester intermediate
Sodium/calcium exchanger membrane region
Peptide methionine sulphoxide reductase MsrA
Methylene-tetrahydrofolate reductase C-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Signal transduction histidine kinase 5TM receptor LytS transmembrane region
Signal transduction histidine kinase internal region
Phosphoribosylformylglycinamidine synthase linker
Positions MEP for the nucleophilic attack
Large ribosomal subunit protein uL15/eL18
Reversibly protonated during proton transport
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
RNA 2-O ribose methyltransferase substrate binding
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Schiff-base intermediate with substrate; via pyruvic acid
RNA polymerase sigma factor 70 region 4 type 2
Phosphocysteine intermediate; for EIIB activity
DNA mismatch repair proteins mutS family
Glucose-6-phosphate isomerase prokaryote
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
ABC transporter substrate-binding protein
RND efflux pump membrane fusion protein barrel-sandwich
DNA replication/recombination mediator RecO N-terminal
ABC transporter substrate-binding protein PnrA-like
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Large ribosomal subunit protein uL6 alpha-beta
Sporulation stage II protein D amidase enhancer LytB N-terminal
Glycoside hydrolase family 42 N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
NADH-rubredoxin oxidoreductase C-terminal
Resolvase/invertase-type recombinase catalytic
Helix-hairpin-helix DNA-binding motif class 1
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein
Polysaccharide biosynthesis protein CapD-like
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Major facilitator superfamily (MFS) profile
Ribose-phosphate pyrophosphokinase N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Copper amine oxidase-like N-terminal domain-containing protein
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Important for interaction with partner proteins
NADH:ubiquinone oxidoreductase-like 20kDa subunit
N-acetylneuraminic acid synthase N-terminal
Translation elongation factor P/YeiP central
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Cysteine sulfenic acid (-SOH) intermediate
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Prokaryotic-type class I peptide chain release factors
Phosphoadenosine phosphosulphate reductase
Glucosamine/galactosamine-6-phosphate isomerase
D-galactose/methyl-galactoside binding periplasmic protein MglB
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Large ribosomal subunit protein uL2 C-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Phosphotransferase system enzyme I N-terminal
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Cytochrome b561 bacterial/Ni-hydrogenase
Flagellar assembly protein FliH/Type III secretion system HrpE
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Nitrite/Sulfite reductase ferredoxin-like
Membrane fusion protein biotin-lipoyl like
Pyruvate phosphate dikinase AMP/ATP-binding
C4-dicarboxylate ABC transporter substrate-binding protein
Small ribosomal subunit protein uS4 N-terminal
Thiamin pyrophosphokinase thiamin-binding
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
RDXXRA motif of the pArg binding pocket involved in allosteric regulation
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Formiminotransferase C-terminal subdomain
Formiminotransferase N-terminal subdomain
Aminoacyl-transfer RNA synthetases class-II family profile
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Aldehyde ferredoxin oxidoreductase N-terminal
Bacterial type II secretion system protein E
Phosphatidic acid phosphatase type 2/haloperoxidase
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Penicillin-binding protein transpeptidase
Type III secretion system flagellar brake protein YcgR PilZN
Transposase IS116/IS110/IS902 C-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Flagellar motor switch protein FliN-like C-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Important for beta-aspartyl-AMP intermediate formation
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
UDP-glucose/GDP-mannose dehydrogenase C-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Involved in ionization of N3 of dUMP, leading to its activation
Cell envelope-related transcriptional attenuator
Membrane fusion protein biotin-lipoyl like domain-containing protein
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Flagellar hook-length control protein-like C-terminal
DNA-directed DNA polymerase family A palm
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Survival protein SurE-like phosphatase/nucleotidase
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Anthranilate synthase component I N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Flagellar Assembly Protein A N-terminal region
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Schiff-base intermediate with acetaldehyde
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Damage-control phosphatase ARMT1-like metal-binding
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Alpha-D-phosphohexomutase alpha/beta/alpha
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase N-terminal
Leucine-binding protein domain-containing protein
CobB/CobQ-like glutamine amidotransferase
Formylmethanofuran dehydrogenase subunit E
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Release factor glutamine methyltransferase N-terminal
Glycosyl transferase family 3 N-terminal
LPS export ABC transporter periplasmic protein LptC
Ribosomal RNA adenine methylase transferase N-terminal
Phosphomannose isomerase type I catalytic
Terminase large subunit-like endonuclease
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Siroheme decarboxylase AsnC-like ligand binding
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Deacetylase PdaC domain-containing protein
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Peptidase M1 membrane alanine aminopeptidase domain-containing protein
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Peptidase S9 prolyl oligopeptidase catalytic
Could be important to modulate the pK values of the two catalytic cysteine residues
Heat-inducible transcription repressor HrcA C-terminal
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
ATPsynthase alpha/beta subunit N-terminal extension
L,D-transpeptidase catalytic domain-containing protein
O-(phosphoribosyl dephospho-coenzyme A)serine
Essential for prephenate dehydratase activity
Cation-transporting P-type ATPase N-terminal
Dinitrogenase iron-molybdenum cofactor biosynthesis
Large ribosomal subunit protein uL30-like ferredoxin-like fold
CD-NTase associated protein 4-like DNA endonuclease
DNA polymerase III delta subunit C-terminal
2,4-diaminopentanoate dehydrogenase C-terminal
Dihydrodipicolinate reductase N-terminal
L-seryl-tRNA selenium transferase N-terminal
Chromosomal replication initiator DnaA C-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Glycosyltransferase subfamily 4-like N-terminal
Alanyl-transfer RNA synthetases family profile
Superoxide dismutase copper/zinc binding
FAD-dependent oxidoreductase 2 FAD binding
Sporulation stage IV protein A C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Spore germination GerAC-like C-terminal domain-containing protein
Integron-associated effector binding protein
Membrane insertase YidC/Oxa/ALB C-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
CAP-associated domain-containing protein
N(4)-bis(aminopropyl)spermidine synthase C-terminal
CO dehydrogenase/acetyl-CoA synthase complex beta subunit C-terminal
Carbon monoxide dehydrogenase subunit alpha ,N-terminal
Bacterial transcription activator effector binding
Periplasmic binding protein domain-containing protein
Involved in allosteric activation by GTP
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Gram-positive cocci surface proteins LPxTG domain-containing protein
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase
BAAT/Acyl-CoA thioester hydrolase C-terminal
Transcriptional coactivator p15 (PC4) C-terminal
Aspartate/homoserine dehydrogenase NAD-binding
High-affinity heme uptake system protein IsdE
Pyrimidine nucleoside phosphorylase C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Sporulation stage II protein D amidase enhancer LytB N-terminal domain-containing protein
Quinolinate phosphoribosyl transferase C-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Putative amidase domain-containing protein
Gly-cisPro motif, important for rejection of L-amino acids
Increases nucleophilicity of active site Cys
D-galactarate/Altronate dehydratase C-terminal
Peptidoglycan binding-like domain-containing protein
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Solute-binding protein family 5 domain-containing protein
ATP-dependent DNA helicase RecG C-terminal
Glycoside hydrolase family 31 N-terminal
Intracellular proteinase inhibitor BsuPI domain-containing protein
Na+/H+ antiporter MnhB subunit-related protein
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
Exonuclease VII large subunit C-terminal
NIF system FeS cluster assembly NifU N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Dihydrodipicolinate reductase C-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Diacylglycerol glucosyltransferase N-terminal
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Peptidase M14 carboxypeptidase A domain-containing protein
General stress protein FMN-binding split barrel
Quinolinate phosphoribosyl transferase N-terminal
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Putative regulatory protein FmdB Zinc ribbon
Pseudouridine synthase I TruA alpha/beta
Sortilin N-terminal domain-containing protein
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Interaction with polymerase core subunit RpoC
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Electron transfer flavoprotein alpha subunit C-terminal
RNA binding; important for wobble base 34 recognition
Na+-translocating membrane potential-generating system MpsC
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
Pyridoxamine 5'-phosphate oxidase putative
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal